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Partners, summaries and graph

PPI neighbourhood (disorder & shared disease context)

Loads a Summary-style interaction graph (IntAct / HIPPIE / BioGRID) with node colour by proteome disorder fraction (blue → red) and a pink border on Cancer Gene Census / compendium drivers. The partner table lists literature support, mutation loads, and how many narrow-matched germline disease groups or somatic cancer-type keys overlap the hub. Germline diseases use a narrow key (e.g. Noonan syndrome 1–4 collapse); somatic cancers use the exact cohort label + source (TCGA, COSMIC, cBioPortal, …).

Same autocomplete as elsewhere — pick a row or type an accession and Load.
SIAH1 example

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ordered-like (low % dis.)
disordered-like (high % dis.)
cancer driver (border)
Graph scope
Nodes shown: —
Driver nodes: —
Top N

Direct partners

Shared germline context (OMIM + ClinVar summaries)

Pick a narrow disease group present on the hub; partners listed below also carry that group in our summary tables. Counts are annotated ordered vs disordered missense in each rollup.

Shared somatic context (cohort missense)

Keys combine source database and cancer / cohort label (exact string). Missense sites are split ordered / disordered using the same combined-disorder threshold as site statistics.