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Total number of binding domains:  227

Identifier UniProt Accession UniProt Gene UniProt Name Chromosome PFAM Domain Start End Database Cancer Driver Number of missense mutations Percent of missense mutation Number of omim mutations Percent of omim mutation Link
ABL1-201 P00519 ABL1 Tyrosine-protein kinase ABL1 chr9 PF07714 242 493 Census, Compendium Yes 30 27.78 % 1 50.00 % link
ABL1-201 P00519 ABL1 Tyrosine-protein kinase ABL1 chr9 PF00018 67 113 Census, Compendium Yes 8 7.41 % 0 0.00 % link
ACE-202 P12821 ACE Angiotensin-converting enzyme chr17 PF01401 643 1221 Not Cancer Driver No 86 55.48 % 0 0.00 % link
AKT1-218 P31749 AKT1 RAC-alpha serine/threonine-protein kinase chr14 PF00433 429 474 Census, Compendium Yes 2 2.02 % 1 25.00 % link
AKT2-206 P31751 AKT2 RAC-beta serine/threonine-protein kinase chr19 PF00069 152 409 Census Yes 35 61.40 % 1 50.00 % link
ANKRA2-201 Q9H9E1 ANKRA2 Ankyrin repeat family A protein 2 chr5 PF12796 134 243 Not Cancer Driver No 12 50.00 % 0 0.00 % link
ANPEP-201 P15144 ANPEP Aminopeptidase N chr15 PF11838 619 946 Not Cancer Driver No 35 27.56 % 0 0.00 % link
AP1G2-202 O75843 AP1G2 AP-1 complex subunit gamma-like 2 chr14 PF02883 668 780 Not Cancer Driver No 7 8.54 % 0 0.00 % link
AP2B1-221 P63010 AP2B1 AP-2 complex subunit beta chr17 PF02883 711 817 Not Cancer Driver No 5 6.25 % 0 0.00 % link
AP2B1-221 P63010 AP2B1 AP-2 complex subunit beta chr17 PF09066 827 935 Not Cancer Driver No 9 11.25 % 0 0.00 % link
AP4M1-201 O00189 AP4M1 AP-4 complex subunit mu-1 chr7 PF00928 173 453 Not Cancer Driver No 25 53.19 % 0 0.00 % link
APBB1-220 O00213 APBB1 Amyloid beta precursor protein binding family B member 1 chr11 PF00640 543 664 Not Cancer Driver No 10 12.50 % 0 0.00 % link
APC-201 P25054 APC Adenomatous polyposis coli protein chr5 PF00514 649 689 Census, Compendium Yes 3 1.02 % 0 0.00 % link
AR-201 P10275 AR Androgen receptor chrX PF00104 690 881 Census, Compendium Yes 35 30.17 % 89 61.81 % link
ATG12-208 O94817 ATG12 Ubiquitin-like protein ATG12 chr5 PF04110 54 140 Not Cancer Driver No 7 53.85 % 0 0.00 % link
ATG5-204 Q9H1Y0 ATG5 Autophagy protein 5 chr6 PF04106 79 270 Not Cancer Driver No 30 90.91 % 1 100.00 % link
BAIAP2-202 Q9UQB8 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 PF08397 17 237 Not Cancer Driver No 18 29.51 % 0 0.00 % link
BAX-202 Q07812 BAX Apoptosis regulator BAX chr19 PF00452 63 158 Census Yes 22 91.67 % 0 0.00 % link
BCL2A1-201 Q16548 BCL2A1 Bcl-2-related protein A1 chr15 PF00452 37 140 Not Cancer Driver No 11 61.11 % 0 0.00 % link
BCL2L1-201 Q07817 BCL2L1 Bcl-2-like protein 1 chr20 PF02180 1 26 Not Cancer Driver No 1 4.55 % 0 0.00 % link
BCL2L1-201 Q07817 BCL2L1 Bcl-2-like protein 1 chr20 PF00452 90 188 Not Cancer Driver No 9 40.91 % 0 0.00 % link
BCL2L2-201 Q92843 BCL2L2 Bcl-2-like protein 2 chr14 PF02180 6 31 Not Cancer Driver No 0 0.00 % 0 0.00 % link
BCL6-202 P41182 BCL6 B-cell lymphoma 6 protein chr3 PF00651 22 129 Census, Compendium Yes 10 10.99 % 0 0.00 % link
BIRC2-201 Q13490 BIRC2 Baculoviral IAP repeat-containing protein 2 chr11 PF00653 272 337 Not Cancer Driver No 8 16.33 % 0 0.00 % link
BIRC5-202 O15392 BIRC5 Baculoviral IAP repeat-containing protein 5 chr17 PF00653 18 88 Not Cancer Driver No 6 37.50 % 0 0.00 % link
C3-201 P01024 C3 Complement C3 chr19 PF01835 129 224 Not Cancer Driver No 16 6.20 % 1 9.09 % link
C8G-201 P07360 C8G Complement component C8 gamma chain chr9 PF00061 48 186 Not Cancer Driver No 8 88.89 % 0 0.00 % link
CASP7-203 P55210 CASP7 Caspase-7 chr10 PF00656 68 301 Not Cancer Driver No 23 82.14 % 0 0.00 % link
CBX1-201 P83916 CBX1 Chromobox protein homolog 1 chr17 PF01393 118 170 Not Cancer Driver No 7 41.18 % 0 0.00 % link
CBX3-202 Q13185 CBX3 Chromobox protein homolog 3 chr7 PF00385 30 79 Not Cancer Driver No 6 33.33 % 0 0.00 % link
CCNA2-201 P20248 CCNA2 Cyclin-A2 chr4 PF02984 309 427 Not Cancer Driver No 12 35.29 % 0 0.00 % link
CCNA2-201 P20248 CCNA2 Cyclin-A2 chr4 PF00134 181 307 Not Cancer Driver No 7 20.59 % 0 0.00 % link
CCNT1-201 O60563 CCNT1 Cyclin-T1 chr12 PF00134 10 149 Not Cancer Driver No 14 21.54 % 0 0.00 % link
CDC20-201 Q12834 CDC20 Cell division cycle protein 20 homolog chr1 PF12894 218 279 Not Cancer Driver No 5 13.89 % 0 0.00 % link
CDK2-201 P24941 CDK2 Cyclin-dependent kinase 2 chr12 PF00069 4 286 Not Cancer Driver No 16 94.12 % 0 0.00 % link
CEP55-201 Q53EZ4 CEP55 Centrosomal protein of 55 kDa chr10 PF12180 171 204 Not Cancer Driver No 2 5.88 % 0 0.00 % link
CETN2-201 P41208 CETN2 Centrin-2 chrX PF13499 103 167 Not Cancer Driver No 7 41.18 % 0 0.00 % link
CHEK1-204 O14757 CHEK1 Serine/threonine-protein kinase Chk1 chr11 PF00069 9 265 Not Cancer Driver No 22 52.38 % 0 0.00 % link
CLIP1-219 P30622 CLIP1 CAP-Gly domain-containing linker protein 1 chr12 PF01302 214 278 Census, Compendium Yes 9 9.18 % 0 0.00 % link
CREBBP-201 Q92793 CREBBP CREB-binding protein chr16 PF00439 1094 1180 Census, Compendium Yes 12 5.50 % 1 3.33 % link
CTNNB1-201 P35222 CTNNB1 Catenin beta-1 chr3 PF00514 583 623 Census, Compendium Yes 8 2.20 % 0 0.00 % link
CTNND1-205 O60716 CTNND1 Catenin delta-1 chr11 PF00514 701 739 Census Yes 5 4.63 % 0 0.00 % link
CTTN-201 Q14247 CTTN Src substrate cortactin chr11 PF14604 499 547 Not Cancer Driver No 13 23.64 % 0 0.00 % link
DCTN1-226 Q14203 DCTN1 Dynactin subunit 1 chr2 PF01302 29 94 Census Yes 6 4.65 % 6 66.67 % link
DCUN1D3-201 Q8IWE4 DCUN1D3 DCN1-like protein 3 chr16 PF03556 162 276 Not Cancer Driver No 14 42.42 % 0 0.00 % link
DDX6-206 P26196 DDX6 Probable ATP-dependent RNA helicase DDX6 chr11 PF00271 320 429 Census, Compendium Yes 10 34.48 % 4 100.00 % link
DLG1-269 Q12959 DLG1 Disks large homolog 1 chr3 PF00595 466 544 Not Cancer Driver No 5 5.62 % 0 0.00 % link
DNAJB1-201 P25685 DNAJB1 DnaJ homolog subfamily B member 1 chr19 PF01556 164 323 Census, Compendium Yes 11 42.31 % 0 0.00 % link
DNMBP-201 Q6XZF7 DNMBP Dynamin-binding protein chr10 PF00018 1519 1568 Not Cancer Driver No 5 3.57 % 0 0.00 % link
DPP3-209 Q9NY33 DPP3 Dipeptidyl peptidase 3 chr11 PF03571 143 704 Not Cancer Driver No 68 76.40 % 0 0.00 % link
DPP4-201 P27487 DPP4 Dipeptidyl peptidase 4 chr2 PF00326 559 765 Not Cancer Driver No 34 31.48 % 0 0.00 % link
DPY30-202 Q9C005 DPY30 Protein dpy-30 homolog chr2 PF05186 52 93 Not Cancer Driver No 4 57.14 % 0 0.00 % link
DYNLL1-201 P63167 DYNLL1 Dynein light chain 1, cytoplasmic chr12 PF01221 5 88 Not Cancer Driver No 7 87.50 % 0 0.00 % link
DYNLL2-201 Q96FJ2 DYNLL2 Dynein light chain 2, cytoplasmic chr17 PF01221 5 88 Not Cancer Driver No 5 100.00 % 0 0.00 % link
EGFR-201 P00533 EGFR Epidermal growth factor receptor chr7 PF01030 361 481 Census, Compendium Yes 23 6.63 % 1 100.00 % link
EGFR-201 P00533 EGFR Epidermal growth factor receptor chr7 PF00757 177 338 Census, Compendium Yes 103 29.68 % 0 0.00 % link
EGLN1-201 Q9GZT9 EGLN1 Egl nine homolog 1 chr1 PF13640 298 391 Not Cancer Driver No 5 22.73 % 2 100.00 % link
EIF4E-203 P06730 EIF4E Eukaryotic translation initiation factor 4E chr4 PF01652 38 197 Not Cancer Driver No 14 77.78 % 0 0.00 % link
ENST00000558468 Q96EP0 RNF31 E3 ubiquitin-protein ligase RNF31 chr14 PF09409 69 150 Not Cancer Driver No 7 6.03 % 0 0.00 % link
EPB41L3-201 Q9Y2J2 EPB41L3 Band 4.1-like protein 3 chr18 PF09379 114 177 Not Cancer Driver No 11 4.58 % 0 0.00 % link
EPHA4-201 P54764 EPHA4 Ephrin type-A receptor 4 chr2 PF01404 31 204 Not Cancer Driver No 24 18.18 % 0 0.00 % link
ERAP2-202 Q6P179 ERAP2 Endoplasmic reticulum aminopeptidase 2 chr5 PF01433 298 541 Not Cancer Driver No 23 31.51 % 0 0.00 % link
ERBIN-201 Q96RT1 ERBIN Erbin chr5 PF00595 1321 1407 Not Cancer Driver No 6 5.31 % 0 0.00 % link
ESR1-201 P03372 ESR1 Estrogen receptor chr6 PF00104 332 531 Census, Compendium Yes 30 32.61 % 2 100.00 % link
ESR2-202 Q92731 ESR2 Estrogen receptor beta chr14 PF00104 283 482 Not Cancer Driver No 19 27.54 % 1 100.00 % link
ESRRA-201 P11474 ESRRA Steroid hormone receptor ERR1 chr11 PF00104 224 404 Compendium Yes 7 25.93 % 0 0.00 % link
ESRRG-209 P62508 ESRRG Estrogen-related receptor gamma chr1 PF00104 255 441 Not Cancer Driver No 46 41.07 % 0 0.00 % link
F11-202 P03951 F11 Coagulation factor XI chr4 PF00089 388 618 Not Cancer Driver No 24 28.24 % 24 42.11 % link
F2-201 P00734 F2 Prothrombin chr11 PF00089 364 613 Not Cancer Driver No 29 34.12 % 6 66.67 % link
FLNA-202 P21333 FLNA Filamin-A chrX PF00630 2554 2643 Census Yes 12 3.81 % 0 0.00 % link
FN1-203 P02751 FN1 Fibronectin chr2 PF00039 2386 2421 Compendium Yes 7 2.40 % 0 0.00 % link
FYN-202 P06241 FYN Tyrosine-protein kinase Fyn chr6 PF00018 88 135 Not Cancer Driver No 7 10.94 % 0 0.00 % link
GABARAP-201 O95166 GABARAP Gamma-aminobutyric acid receptor-associated protein chr17 PF02991 13 116 Not Cancer Driver No 7 100.00 % 0 0.00 % link
GALNT2-201 Q10471 GALNT2 Polypeptide N-acetylgalactosaminyltransferase 2 chr1 PF00652 446 563 Not Cancer Driver No 15 21.43 % 0 0.00 % link
GALNT2-201 Q10471 GALNT2 Polypeptide N-acetylgalactosaminyltransferase 2 chr1 PF00535 139 322 Not Cancer Driver No 28 40.00 % 1 50.00 % link
GEMIN2-202 O14893 GEMIN2 Gem-associated protein 2 chr14 PF04938 37 273 Not Cancer Driver No 14 82.35 % 0 0.00 % link
GGA1-203 Q9UJY5 GGA1 ADP-ribosylation factor-binding protein GGA1 chr22 PF00790 5 143 Not Cancer Driver No 12 21.05 % 0 0.00 % link
GGA1-203 Q9UJY5 GGA1 ADP-ribosylation factor-binding protein GGA1 chr22 PF02883 513 631 Not Cancer Driver No 14 24.56 % 0 0.00 % link
GGA3-201 Q9NZ52 GGA3 ADP-ribosylation factor-binding protein GGA3 chr17 PF00790 3 142 Not Cancer Driver No 10 19.61 % 0 0.00 % link
GOPC-202 Q9HD26 GOPC Golgi-associated PDZ and coiled-coil motif-containing protein chr6 PF00595 288 368 Census Yes 8 20.00 % 0 0.00 % link
GORASP1-201 Q9BQQ3 GORASP1 Golgi reassembly-stacking protein 1 chr3 PF04495 69 205 Not Cancer Driver No 14 41.18 % 0 0.00 % link
GP1BA-201 P07359 GP1BA Platelet glycoprotein Ib alpha chain chr17 PF13855 116 174 Not Cancer Driver No 6 18.18 % 3 37.50 % link
GPSM2-201 P81274 GPSM2 G-protein-signaling modulator 2 chr1 PF13176 204 239 Not Cancer Driver No 0 0.00 % 0 0.00 % link
GRB7-201 Q14451 GRB7 Growth factor receptor-bound protein 7 chr17 PF00017 431 512 Not Cancer Driver No 7 11.48 % 0 0.00 % link
GSK3B-201 P49841 GSK3B Glycogen synthase kinase-3 beta chr3 PF00069 56 340 Not Cancer Driver No 29 85.29 % 0 0.00 % link
GZMH-201 P20718 GZMH Granzyme H chr14 PF00089 21 239 Not Cancer Driver No 30 88.24 % 0 0.00 % link
GZMM-201 P51124 GZMM Granzyme M chr19 PF00089 26 249 Not Cancer Driver No 21 87.50 % 0 0.00 % link
HAT1-201 O14929 HAT1 Histone acetyltransferase type B catalytic subunit chr2 PF10394 25 187 Not Cancer Driver No 9 27.27 % 0 0.00 % link
HGFAC-201 Q04756 HGFAC Hepatocyte growth factor activator chr4 PF00089 408 641 Not Cancer Driver No 28 38.89 % 0 0.00 % link
HIF1AN-201 Q9NWT6 HIF1AN Hypoxia-inducible factor 1-alpha inhibitor chr10 PF13621 48 302 Not Cancer Driver No 22 91.67 % 0 0.00 % link
HLA-B-249 P01889 HLA-B HLA class I histocompatibility antigen, B alpha chain chr6 PF07654 211 290 Compendium Yes 22 44.90 % 0 0.00 % link
HLA-B-249 P01889 HLA-B HLA class I histocompatibility antigen, B alpha chain chr6 PF00129 25 203 Compendium Yes 13 26.53 % 0 0.00 % link
HLA-E-201 P13747 HLA-E HLA class I histocompatibility antigen, alpha chain E chr6 PF07654 207 287 Not Cancer Driver No 14 35.00 % 0 0.00 % link
HLA-E-201 P13747 HLA-E HLA class I histocompatibility antigen, alpha chain E chr6 PF00129 22 200 Not Cancer Driver No 15 37.50 % 0 0.00 % link
HLA-G-201 P17693 HLA-G HLA class I histocompatibility antigen, alpha chain G chr6 PF00129 25 203 Not Cancer Driver No 21 40.38 % 0 0.00 % link
HLA-G-201 P17693 HLA-G HLA class I histocompatibility antigen, alpha chain G chr6 PF07654 211 290 Not Cancer Driver No 18 34.62 % 0 0.00 % link
HNF4A-201 P41235 HNF4A Hepatocyte nuclear factor 4-alpha chr20 PF00104 172 361 Not Cancer Driver No 35 30.97 % 1 20.00 % link
IGF1R-217 P08069 IGF1R Insulin-like growth factor 1 receptor chr15 PF07714 999 1266 Not Cancer Driver No 22 15.38 % 1 16.67 % link
INSR-201 P06213 INSR Insulin receptor chr19 PF07714 1023 1290 Not Cancer Driver No 35 25.18 % 19 30.16 % link
INTS3-201 Q68E01 INTS3 Integrator complex subunit 3 chr1 PF10189 271 495 Not Cancer Driver No 20 21.98 % 0 0.00 % link
ITCH-201 Q96J02 ITCH E3 ubiquitin-protein ligase Itchy homolog chr20 PF00397 480 509 Not Cancer Driver No 1 1.33 % 0 0.00 % link
KAT6A-201 Q92794 KAT6A Histone acetyltransferase KAT6A chr8 PF00628 264 313 Census, Compendium Yes 3 2.52 % 0 0.00 % link
KDM1B-205 Q8NB78 KDM1B Lysine-specific histone demethylase 2 chr6 PF03486 355 635 Not Cancer Driver No 19 32.76 % 0 0.00 % link
KDM1B-205 Q8NB78 KDM1B Lysine-specific histone demethylase 2 chr6 PF07992 355 635 Not Cancer Driver No 19 32.76 % 0 0.00 % link
KLHL2-201 O95198 KLHL2 Kelch-like protein 2 chr4 PF01344 532 577 Not Cancer Driver No 7 12.96 % 0 0.00 % link
KLHL3-201 Q9UH77 KLHL3 Kelch-like protein 3 chr5 PF01344 526 571 Not Cancer Driver No 4 7.41 % 4 13.79 % link
KLK4-201 Q9Y5K2 KLK4 Kallikrein-4 chr19 PF00089 31 247 Not Cancer Driver No 37 97.37 % 0 0.00 % link
KPNA2-201 P52292 KPNA2 Importin subunit alpha-1 chr17 PF00514 409 448 Not Cancer Driver No 3 5.45 % 0 0.00 % link
KPNB1-201 Q14974 KPNB1 Importin subunit beta-1 chr17 PF03810 21 101 Not Cancer Driver No 6 7.59 % 0 0.00 % link
KRIT1-203 O00522 KRIT1 Krev interaction trapped protein 1 chr7 PF00373 517 640 Not Cancer Driver No 8 12.31 % 1 50.00 % link
LCN2-201 P80188 LCN2 Neutrophil gelatinase-associated lipocalin chr9 PF00061 48 193 Not Cancer Driver No 10 50.00 % 0 0.00 % link
LGALS8-206 O00214 LGALS8 Galectin-8 chr1 PF00337 186 316 Not Cancer Driver No 11 36.67 % 0 0.00 % link
LIG4-202 P49917 LIG4 DNA ligase 4 chr13 PF04675 15 208 Not Cancer Driver No 13 12.62 % 0 0.00 % link
LRP6-201 O75581 LRP6 Low-density lipoprotein receptor-related protein 6 chr12 PF14670 893 929 Not Cancer Driver No 1 0.68 % 0 0.00 % link
MAD2L1-201 Q13257 MAD2L1 Mitotic spindle assembly checkpoint protein MAD2A chr4 PF02301 16 196 Not Cancer Driver No 15 71.43 % 0 0.00 % link
MAD2L2-207 Q9UI95 MAD2L2 Mitotic spindle assembly checkpoint protein MAD2B chr1 PF02301 16 135 Not Cancer Driver No 6 37.50 % 1 100.00 % link
MAPK1-201 P28482 MAPK1 Mitogen-activated protein kinase 1 chr22 PF00069 25 313 Census, Compendium Yes 28 53.85 % 3 50.00 % link
MAPK10-319 P53779 MAPK10 Mitogen-activated protein kinase 10 chr4 PF00069 64 359 Not Cancer Driver No 52 72.22 % 0 0.00 % link
MAPK14-201 Q16539 MAPK14 Mitogen-activated protein kinase 14 chr6 PF00069 24 308 Not Cancer Driver No 21 95.45 % 0 0.00 % link
MAPK8-206 P45983 MAPK8 Mitogen-activated protein kinase 8 chr10 PF00069 26 321 Not Cancer Driver No 40 76.92 % 0 0.00 % link
MAPRE1-201 Q15691 MAPRE1 Microtubule-associated protein RP/EB family member 1 chr20 PF03271 210 248 Not Cancer Driver No 1 5.88 % 0 0.00 % link
MARK2-204 Q7KZI7 MARK2 Serine/threonine-protein kinase MARK2 chr11 PF00627 324 360 Compendium Yes 4 4.76 % 0 0.00 % link
MASP2-201 O00187 MASP2 Mannan-binding lectin serine protease 2 chr1 PF00089 445 679 Not Cancer Driver No 20 25.64 % 0 0.00 % link
MCL1-202 Q07820 MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 PF00452 213 312 Not Cancer Driver No 10 37.04 % 0 0.00 % link
MDM2-224 Q00987 MDM2 E3 ubiquitin-protein ligase Mdm2 chr12 PF02201 26 101 Census, Compendium Yes 4 10.26 % 0 0.00 % link
MDM4-203 O15151 MDM4 Protein Mdm4 chr1 PF02201 25 95 Census, Compendium Yes 4 12.12 % 0 0.00 % link
MOB1A-201 Q9H8S9 MOB1A MOB kinase activator 1A chr2 PF03637 33 204 Not Cancer Driver No 12 100.00 % 0 0.00 % link
NAA40-202 Q86UY6 NAA40 N-alpha-acetyltransferase 40 chr11 PF00583 71 192 Not Cancer Driver No 8 47.06 % 0 0.00 % link
NCF1-201 P14598 NCF1 Neutrophil cytosol factor 1 chr7 PF00018 232 277 Not Cancer Driver No 0 0.00 % 0 0.00 % link
NPR3-201 P17342 NPR3 Atrial natriuretic peptide receptor 3 chr5 PF01094 71 425 Not Cancer Driver No 64 81.01 % 2 100.00 % link
NR1H2-201 P55055 NR1H2 Oxysterols receptor LXR-beta chr19 PF00104 256 444 Not Cancer Driver No 13 34.21 % 0 0.00 % link
NR1H3-211 Q13133 NR1H3 Oxysterols receptor LXR-alpha chr11 PF00104 243 431 Not Cancer Driver No 14 31.82 % 0 0.00 % link
NR1H4-209 Q96RI1 NR1H4 Bile acid receptor chr12 PF00104 289 471 Not Cancer Driver No 21 25.61 % 0 0.00 % link
NR1I2-202 O75469 NR1I2 Nuclear receptor subfamily 1 group I member 2 chr3 PF00104 238 415 Not Cancer Driver No 15 33.33 % 0 0.00 % link
NR3C1-203 P04150 NR3C1 Glucocorticoid receptor chr5 PF00104 549 741 Not Cancer Driver No 15 27.27 % 7 63.64 % link
NR3C2-203 P08235 NR3C2 Mineralocorticoid receptor chr4 PF00104 757 946 Not Cancer Driver No 20 16.67 % 9 64.29 % link
NR5A1-202 Q13285 NR5A1 Steroidogenic factor 1 chr9 PF00104 250 442 Not Cancer Driver No 14 33.33 % 3 13.04 % link
NR5A2-203 O00482 NR5A2 Nuclear receptor subfamily 5 group A member 2 chr1 PF00104 330 523 Not Cancer Driver No 34 34.00 % 0 0.00 % link
OGT-202 O15294 OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX PF13844 476 1016 Not Cancer Driver No 64 57.66 % 0 0.00 % link
OGT-202 O15294 OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX PF13414 436 474 Not Cancer Driver No 4 3.60 % 0 0.00 % link
OXSR1-201 O95747 OXSR1 Serine/threonine-protein kinase OSR1 chr3 PF12202 434 491 Not Cancer Driver No 9 17.65 % 0 0.00 % link
PABPC1-201 P11940 PABPC1 Polyadenylate-binding protein 1 chr8 PF00658 547 614 Census, Compendium Yes 5 9.43 % 0 0.00 % link
PADI4-201 Q9UM07 PADI4 Protein-arginine deiminase type-4 chr1 PF03068 283 660 Not Cancer Driver No 66 67.35 % 0 0.00 % link
PADI4-201 Q9UM07 PADI4 Protein-arginine deiminase type-4 chr1 PF08526 1 111 Not Cancer Driver No 17 17.35 % 0 0.00 % link
PADI4-201 Q9UM07 PADI4 Protein-arginine deiminase type-4 chr1 PF08527 113 273 Not Cancer Driver No 14 14.29 % 0 0.00 % link
PAK4-203 O96013 PAK4 Serine/threonine-protein kinase PAK 4 chr19 PF00069 321 572 Not Cancer Driver No 17 36.96 % 0 0.00 % link
PCID2-202 Q5JVF3 PCID2 PCI domain-containing protein 2 chr13 PF01399 277 388 Not Cancer Driver No 6 17.65 % 0 0.00 % link
PCNA-201 P12004 PCNA Proliferating cell nuclear antigen chr20 PF00705 1 125 Not Cancer Driver No 8 42.11 % 0 0.00 % link
PCNA-201 P12004 PCNA Proliferating cell nuclear antigen chr20 PF02747 127 254 Not Cancer Driver No 11 57.89 % 1 100.00 % link
PDCD10-201 Q9BUL8 PDCD10 Programmed cell death protein 10 chr3 PF06840 14 161 Not Cancer Driver No 19 76.00 % 0 0.00 % link
PDCD6-201 O75340 PDCD6 Programmed cell death protein 6 chr5 PF13499 92 156 Not Cancer Driver No 7 43.75 % 0 0.00 % link
PDCD6-201 O75340 PDCD6 Programmed cell death protein 6 chr5 PF13202 30 53 Not Cancer Driver No 3 18.75 % 0 0.00 % link
PDCD6IP-201 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein chr3 PF03097 4 378 Not Cancer Driver No 28 48.28 % 0 0.00 % link
PDPK1-202 O15530 PDPK1 3-phosphoinositide-dependent protein kinase 1 chr16 PF00069 82 342 Not Cancer Driver No 3 13.04 % 0 0.00 % link
PEX3-201 P56589 PEX3 Peroxisomal biogenesis factor 3 chr6 PF04882 94 364 Not Cancer Driver No 15 83.33 % 2 100.00 % link
PEX5-221 P50542 PEX5 Peroxisomal targeting signal 1 receptor chr12 PF13181 556 589 Not Cancer Driver No 5 9.62 % 0 0.00 % link
PFN1-201 P07737 PFN1 Profilin-1 chr17 PF00235 2 140 Not Cancer Driver No 13 100.00 % 3 100.00 % link
PGC-202 P20142 PGC Gastricsin chr6 PF00026 72 387 Not Cancer Driver No 36 73.47 % 0 0.00 % link
PGR-202 P06401 PGR Progesterone receptor chr11 PF00104 704 891 Not Cancer Driver No 39 28.68 % 0 0.00 % link
PIM1-201 P11309 PIM1 Serine/threonine-protein kinase pim-1 chr6 PF00069 38 290 Census, Compendium Yes 47 77.05 % 0 0.00 % link
PLAU-201 P00749 PLAU Urokinase-type plasminogen activator chr10 PF00089 179 419 Not Cancer Driver No 28 54.90 % 0 0.00 % link
PPARA-202 Q07869 PPARA Peroxisome proliferator-activated receptor alpha chr22 PF00104 264 449 Not Cancer Driver No 16 32.65 % 0 0.00 % link
PPARG-201 P37231 PPARG Peroxisome proliferator-activated receptor gamma chr3 PF00104 299 486 Census Yes 21 35.00 % 2 66.67 % link
PPP1CA-203 P62136 PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 PF00149 57 252 Not Cancer Driver No 17 54.84 % 0 0.00 % link
PPP3CA-203 Q08209 PPP3CA Protein phosphatase 3 catalytic subunit alpha chr4 PF00149 83 285 Compendium Yes 19 30.16 % 5 71.43 % link
PRKACA-201 P17612 PRKACA cAMP-dependent protein kinase catalytic subunit alpha chr19 PF00069 44 298 Census Yes 46 93.88 % 2 100.00 % link
PRMT5-202 O14744 PRMT5 Protein arginine N-methyltransferase 5 chr14 PF05185 295 464 Not Cancer Driver No 16 25.81 % 0 0.00 % link
PTBP1-203 P26599 PTBP1 Polypyrimidine tract-binding protein 1 chr19 PF00076 456 521 Not Cancer Driver No 2 3.03 % 0 0.00 % link
PTPN13-202 Q12923 PTPN13 Tyrosine-protein phosphatase non-receptor type 13 chr4 PF00595 1883 1961 Census, Compendium Yes 5 2.33 % 0 0.00 % link
PTPN18-201 Q99952 PTPN18 Tyrosine-protein phosphatase non-receptor type 18 chr2 PF00102 56 290 Not Cancer Driver No 29 69.05 % 0 0.00 % link
PTPN4-201 P29074 PTPN4 Tyrosine-protein phosphatase non-receptor type 4 chr2 PF00595 517 602 Not Cancer Driver No 8 7.34 % 0 0.00 % link
RARA-201 P10276 RARA Retinoic acid receptor alpha chr17 PF00104 224 401 Census, Compendium Yes 32 53.33 % 0 0.00 % link
RB1-201 P06400 RB1 Retinoblastoma-associated protein chr13 PF01857 646 765 Census, Compendium Yes 19 21.35 % 8 38.10 % link
RBBP4-202 Q09028 RBBP4 Histone-binding protein RBBP4 chr1 PF12265 19 88 Not Cancer Driver No 7 17.50 % 0 0.00 % link
RBBP4-202 Q09028 RBBP4 Histone-binding protein RBBP4 chr1 PF00400 364 403 Not Cancer Driver No 4 10.00 % 0 0.00 % link
RBBP7-203 Q16576 RBBP7 Histone-binding protein RBBP7 chrX PF00400 363 402 Not Cancer Driver No 3 7.14 % 0 0.00 % link
RBM17-201 Q96I25 RBM17 Splicing factor 45 chr10 PF00076 323 383 Not Cancer Driver No 5 12.20 % 0 0.00 % link
RFXANK-201 O14593 RFXANK DNA-binding protein RFXANK chr19 PF00023 134 243 Not Cancer Driver No 8 61.54 % 1 100.00 % link
RIOX1-201 Q9H6W3 RIOX1 Ribosomal oxygenase 1 chr14 PF08007 215 557 Not Cancer Driver No 0 0.00 % 0 0.00 % link
RIOX2-203 Q8IUF8 RIOX2 Ribosomal oxygenase 2 chr3 PF08007 51 364 Not Cancer Driver No 23 69.70 % 0 0.00 % link
RNF2-202 Q99496 RNF2 E3 ubiquitin-protein ligase RING2 chr1 PF16207 246 330 Not Cancer Driver No 6 23.08 % 0 0.00 % link
RNF31-201 Q96EP0 RNF31 E3 ubiquitin-protein ligase RNF31 chr14 PF09409 69 150 Not Cancer Driver No 7 6.03 % 0 0.00 % link
RORA-203 P35398 RORA Nuclear receptor ROR-alpha chr15 PF00104 305 494 Not Cancer Driver No 14 32.56 % 2 50.00 % link
RORC-201 P51449 RORC Nuclear receptor ROR-gamma chr1 PF00104 310 488 Not Cancer Driver No 23 28.40 % 0 0.00 % link
RPL11-206 P62913 RPL11 Large ribosomal subunit protein uL5 chr1 PF00281 10 63 Not Cancer Driver No 6 31.58 % 1 100.00 % link
RPRD1B-201 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 PF04818 7 125 Not Cancer Driver No 10 43.48 % 0 0.00 % link
RXRA-202 P19793 RXRA Retinoic acid receptor RXR-alpha chr9 PF00104 257 442 Compendium Yes 42 60.00 % 0 0.00 % link
S100A10-202 P60903 S100A10 Protein S100-A10 chr1 PF01023 5 44 Not Cancer Driver No 2 22.22 % 0 0.00 % link
S100A4-204 P26447 S100A4 Protein S100-A4 chr1 PF01023 5 47 Not Cancer Driver No 1 16.67 % 0 0.00 % link
SDCBP-201 O00560 SDCBP Syntenin-1 chr8 PF00595 198 270 Not Cancer Driver No 7 30.43 % 0 0.00 % link
SERPINE1-201 P05121 SERPINE1 Plasminogen activator inhibitor 1 chr7 PF00079 33 402 Not Cancer Driver No 55 88.71 % 0 0.00 % link
SETD7-201 Q8WTS6 SETD7 Histone-lysine N-methyltransferase SETD7 chr4 PF00856 170 336 Not Cancer Driver No 11 42.31 % 0 0.00 % link
SF3B6-201 Q9Y3B4 SF3B6 Splicing factor 3B subunit 6 chr2 PF00076 21 88 Not Cancer Driver No 3 42.86 % 0 0.00 % link
SH2D1A-202 O60880 SH2D1A SH2 domain-containing protein 1A chrX PF00017 6 87 Not Cancer Driver No 22 78.57 % 16 84.21 % link
SIRT2-201 Q8IXJ6 SIRT2 NAD-dependent protein deacetylase sirtuin-2 chr19 PF02146 84 268 Not Cancer Driver No 21 52.50 % 0 0.00 % link
SIRT5-205 Q9NXA8 SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial chr6 PF02146 58 256 Not Cancer Driver No 13 59.09 % 0 0.00 % link
SMAD2-201 Q15796 SMAD2 Mothers against decapentaplegic homolog 2 chr18 PF03166 272 443 Census, Compendium Yes 26 44.83 % 2 66.67 % link
SMYD2-201 Q9NRG4 SMYD2 N-lysine methyltransferase SMYD2 chr1 PF01753 52 90 Not Cancer Driver No 2 7.41 % 0 0.00 % link
SPIRE1-202 Q08AE8 SPIRE1 Protein spire homolog 1 chr18 PF16474 40 236 Not Cancer Driver No 4 8.70 % 0 0.00 % link
SPOP-206 O43791 SPOP Speckle-type POZ protein chr17 PF00917 38 163 Census, Compendium Yes 110 80.88 % 5 83.33 % link
SPSB1-201 Q96BD6 SPSB1 SPRY domain-containing SOCS box protein 1 chr1 PF00622 97 228 Not Cancer Driver No 14 50.00 % 0 0.00 % link
SPSB2-205 Q99619 SPSB2 SPRY domain-containing SOCS box protein 2 chr12 PF00622 88 218 Not Cancer Driver No 18 60.00 % 0 0.00 % link
STAMBP-202 O95630 STAMBP STAM-binding protein chr2 PF08969 8 117 Not Cancer Driver No 11 25.58 % 5 83.33 % link
STIP1-201 P31948 STIP1 Stress-induced-phosphoprotein 1 chr11 PF13181 428 461 Not Cancer Driver No 4 7.41 % 0 0.00 % link
STIP1-201 P31948 STIP1 Stress-induced-phosphoprotein 1 chr11 PF00515 36 69 Not Cancer Driver No 2 3.70 % 0 0.00 % link
SUFU-202 Q9UMX1 SUFU Suppressor of fused homolog chr10 PF05076 64 241 Census Yes 14 29.17 % 1 50.00 % link
SUMF1-201 Q8NBK3 SUMF1 Formylglycine-generating enzyme chr3 PF03781 87 367 Not Cancer Driver No 20 74.07 % 14 93.33 % link
TAX1BP3-201 O14907 TAX1BP3 Tax1-binding protein 3 chr17 PF00595 17 110 Not Cancer Driver No 9 75.00 % 0 0.00 % link
TERF2-201 Q15554 TERF2 Telomeric repeat-binding factor 2 chr16 PF08558 94 293 Not Cancer Driver No 10 38.46 % 0 0.00 % link
TIAM1-206 Q13009 TIAM1 Rho guanine nucleotide exchange factor TIAM1 chr21 PF00595 845 925 Not Cancer Driver No 9 3.42 % 0 0.00 % link
TJP1-201 Q07157 TJP1 Tight junction protein ZO-1 chr15 PF00595 422 501 Not Cancer Driver No 7 4.90 % 0 0.00 % link
TJP1-201 Q07157 TJP1 Tight junction protein ZO-1 chr15 PF07653 520 582 Not Cancer Driver No 2 1.40 % 0 0.00 % link
TLE1-203 Q04724 TLE1 Transducin-like enhancer protein 1 chr9 PF00400 606 644 Not Cancer Driver No 8 9.20 % 0 0.00 % link
TNKS2-201 Q9H2K2 TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 PF13637 679 732 Not Cancer Driver No 4 4.00 % 0 0.00 % link
TNKS2-201 Q9H2K2 TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 PF12796 556 622 Not Cancer Driver No 1 1.00 % 0 0.00 % link
TNPO1-201 Q92973 TNPO1 Transportin-1 chr5 PF03810 41 109 Not Cancer Driver No 4 6.06 % 0 0.00 % link
TP53BP1-201 Q12888 TP53BP1 TP53-binding protein 1 chr15 PF09038 1483 1604 Not Cancer Driver No 8 5.03 % 0 0.00 % link
TPST2-201 O60704 TPST2 Protein-tyrosine sulfotransferase 2 chr22 PF13469 69 262 Not Cancer Driver No 23 60.53 % 0 0.00 % link
TSG101-201 Q99816 TSG101 Tumor susceptibility gene 101 protein chr11 PF05743 21 141 Not Cancer Driver No 7 22.58 % 0 0.00 % link
TYMS-203 P04818 TYMS Thymidylate synthase chr18 PF00303 31 313 Not Cancer Driver No 18 100.00 % 0 0.00 % link
UBE2B-201 P63146 UBE2B Ubiquitin-conjugating enzyme E2 B chr5 PF00179 8 145 Not Cancer Driver No 9 100.00 % 0 0.00 % link
UHRF1-208 Q96T88 UHRF1 E3 ubiquitin-protein ligase UHRF1 chr19 PF00628 317 366 Not Cancer Driver No 0 0.00 % 0 0.00 % link
USP7-201 Q93009 USP7 Ubiquitin carboxyl-terminal hydrolase 7 chr16 PF00917 74 196 Not Cancer Driver No 12 8.89 % 0 0.00 % link
VPS4B-201 O75351 VPS4B Vacuolar protein sorting-associated protein 4B chr18 PF04212 8 74 Not Cancer Driver No 4 12.12 % 0 0.00 % link
VTA1-202 Q9NP79 VTA1 Vacuolar protein sorting-associated protein VTA1 homolog chr6 PF04652 16 158 Not Cancer Driver No 15 45.45 % 0 0.00 % link
WDR5-201 P61964 WDR5 WD repeat-containing protein 5 chr9 PF00400 291 331 Not Cancer Driver No 5 27.78 % 0 0.00 % link
YWHAZ-207 P63104 YWHAZ 14-3-3 protein zeta/delta chr8 PF00244 9 229 Not Cancer Driver No 17 89.47 % 0 0.00 % link