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Total number of Phase separated region: 68
Identifier | UniProt Accession | UniProt Gene | UniProt Name | Chromosome | PFAM Domain | Start | End | Database | Cancer Driver | Number of missense mutations | Percent of missense mutation | Number of omim mutations | Percent of omim mutation | Link |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AGO2-201 | Q9UKV8 | AGO2 | Protein argonaute-2 | chr8 | 29576456 | 517 | 818 | Not Cancer Driver | No | 33 | 36.26 % | 4 | 40.00 % | link |
APP-201 | P05067 | APP | Amyloid-beta precursor protein | chr21 | 30401430 | 672 | 713 | Not Cancer Driver | No | 5 | 5.32 % | 7 | 58.33 % | link |
BRD4-213 | O60885 | BRD4 | Bromodomain-containing protein 4 | chr19 | 29930091 | 674 | 1351 | Census, Compendium | Yes | 73 | 51.05 % | 0 | 0.00 % | link |
CBX2-202 | Q14781 | CBX2 | Chromobox protein homolog 2 | chr17 | 30514760 | 1 | 532 | Not Cancer Driver | No | 45 | 100.00 % | 2 | 100.00 % | link |
CBX5-201 | P45973 | CBX5 | Chromobox protein homolog 5 | chr12 | 28636604 | 1 | 177 | Not Cancer Driver | No | 12 | 80.00 % | 0 | 0.00 % | link |
CCNT1-201 | O60563 | CCNT1 | Cyclin-T1 | chr12 | 29849146 | 462 | 654 | Not Cancer Driver | No | 17 | 26.15 % | 0 | 0.00 % | link |
CGAS-201 | Q8N884 | CGAS | Cyclic GMP-AMP synthase | chr6 | 29976794 | 1 | 146 | Not Cancer Driver | No | 4 | 12.12 % | 0 | 0.00 % | link |
CGAS-201 | Q8N884 | CGAS | Cyclic GMP-AMP synthase | chr6 | 29976794 | 161 | 522 | Not Cancer Driver | No | 27 | 81.82 % | 0 | 0.00 % | link |
CPEB3-201 | Q8NE35 | CPEB3 | Cytoplasmic polyadenylation element-binding protein 3 | chr10 | 31416913 | 1 | 698 | Census, Compendium | Yes | 48 | 100.00 % | 0 | 0.00 % | link |
DAXX-202 | Q9UER7 | DAXX | Death domain-associated protein 6 | chr6 | 30244836 | 495 | 740 | Census, Compendium | Yes | 24 | 30.38 % | 0 | 0.00 % | link |
DDX3X-244 | O00571 | DDX3X | ATP-dependent RNA helicase DDX3X | chrX | 30531905 | 1 | 168 | Census, Compendium | Yes | 21 | 23.08 % | 0 | 0.00 % | link |
DDX4-204 | Q9NQI0 | DDX4 | Probable ATP-dependent RNA helicase DDX4 | chr5 | 25747659 | 1 | 236 | Not Cancer Driver | No | 27 | 28.72 % | 0 | 0.00 % | link |
DYRK1A-214 | Q13627 | DYRK1A | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | 29849146 | 491 | 686 | Not Cancer Driver | No | 0 | 0.00 % | 0 | 0.00 % | link |
DYRK3-203 | O43781 | DYRK3 | Dual specificity tyrosine-phosphorylation-regulated kinase 3 | chr1 | 23415227 | 1 | 188 | Not Cancer Driver | No | 11 | 20.37 % | 0 | 0.00 % | link |
ELN-235 | P15502 | ELN | Elastin | chr7 | 24727034 | 27 | 786 | Census, Compendium | Yes | 1 | 100.00 % | 0 | 0.00 % | link |
ESR1-201 | P03372 | ESR1 | Estrogen receptor | chr6 | 30833784 | 79 | 174 | Census, Compendium | Yes | 6 | 6.52 % | 0 | 0.00 % | link |
EWSR1-206 | Q01844 | EWSR1 | RNA-binding protein EWS | chr22 | 26286827 | 1 | 285 | Census, Compendium | Yes | 0 | 0.00 % | 0 | 0.00 % | link |
EWSR1-206 | Q01844 | EWSR1 | RNA-binding protein EWS | chr22 | 26286827 | 286 | 360 | Census, Compendium | Yes | 13 | 61.90 % | 0 | 0.00 % | link |
EWSR1-206 | Q01844 | EWSR1 | RNA-binding protein EWS | chr22 | 26286827 | 361 | 447 | Census, Compendium | Yes | 8 | 38.10 % | 0 | 0.00 % | link |
FMR1-205 | Q06787 | FMR1 | Fragile X messenger ribonucleoprotein 1 | chrX | 30765518 | 445 | 632 | Not Cancer Driver | No | 32 | 34.78 % | 0 | 0.00 % | link |
FUS-201 | P35637 | FUS | RNA-binding protein FUS | chr16 | 29961577 | 1 | 526 | Census | Yes | 27 | 100.00 % | 16 | 100.00 % | link |
GATA3-201 | P23771 | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | 30833784 | 105 | 260 | Census, Compendium | Yes | 36 | 34.95 % | 0 | 0.00 % | link |
GRB2-202 | P62993 | GRB2 | Growth factor receptor-bound protein 2 | chr17 | 27056844 | 1 | 217 | Not Cancer Driver | No | 21 | 100.00 % | 0 | 0.00 % | link |
HNRNPA1-202 | P09651 | HNRNPA1 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | 26406374 | 186 | 372 | Not Cancer Driver | No | 0 | 0.00 % | 4 | 100.00 % | link |
HNRNPD-201 | Q14103 | HNRNPD | Heterogeneous nuclear ribonucleoprotein D0 | chr4 | 27377249 | 1 | 355 | Not Cancer Driver | No | 28 | 100.00 % | 0 | 0.00 % | link |
HSPB2-201 | Q16082 | HSPB2 | Heat shock protein beta-2 | chr11 | 28854361 | 147 | 182 | Not Cancer Driver | No | 5 | 31.25 % | 0 | 0.00 % | link |
HSPB2-C11orf52-201 | Q16082 | HSPB2 | Heat shock protein beta-2 | chr11 | 28854361 | 147 | 182 | Not Cancer Driver | No | 5 | 31.25 % | 0 | 0.00 % | link |
KHDRBS1-202 | Q07666 | KHDRBS1 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | chr1 | 27377249 | 1 | 197 | Not Cancer Driver | No | 5 | 11.90 % | 0 | 0.00 % | link |
LAT-201 | O43561 | LAT | Linker for activation of T-cells family member 1 | chr16 | 27056844 | 28 | 262 | Not Cancer Driver | No | 20 | 100.00 % | 0 | 0.00 % | link |
LGALS3-201 | P17931 | LGALS3 | Galectin-3 | chr14 | 28893908 | 20 | 100 | Not Cancer Driver | No | 0 | 0.00 % | 0 | 0.00 % | link |
MATR3-201 | P43243 | MATR3 | Matrin-3 | chr5 | 31019288 | 1 | 397 | Not Cancer Driver | No | 37 | 45.68 % | 2 | 66.67 % | link |
MED1-201 | Q15648 | MED1 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | 29930091 | 948 | 1574 | Not Cancer Driver | No | 9 | 11.11 % | 0 | 0.00 % | link |
MORC3-201 | Q14149 | MORC3 | MORC family CW-type zinc finger protein 3 | chr21 | 31284181 | 1 | 400 | Not Cancer Driver | No | 26 | 34.67 % | 0 | 0.00 % | link |
NCK1-207 | P16333 | NCK1 | Cytoplasmic protein NCK1 | chr3 | 26553976 | 1 | 377 | Not Cancer Driver | No | 41 | 100.00 % | 0 | 0.00 % | link |
NONO-201 | Q15233 | NONO | Non-POU domain-containing octamer-binding protein | chrX | 29932899 | 218 | 272 | Census, Compendium | Yes | 9 | 12.86 % | 0 | 0.00 % | link |
NPHS1-202 | O60500 | NPHS1 | Nephrin | chr19 | 26553976 | 1077 | 1241 | Not Cancer Driver | No | 43 | 23.37 % | 1 | 1.72 % | link |
NPM1-201 | P06748 | NPM1 | Nucleophosmin | chr5 | 26836305 | 1 | 294 | Census, Compendium | Yes | 25 | 100.00 % | 0 | 0.00 % | link |
NUP98-203 | P52948 | NUP98 | Nuclear pore complex protein Nup98-Nup96 | chr11 | 25562883 | 1 | 500 | Census | Yes | 38 | 23.60 % | 0 | 0.00 % | link |
POLR2A-210 | P24928 | POLR2A | DNA-directed RNA polymerase II subunit RPB1 | chr17 | 30127355 | 1593 | 1960 | Census | Yes | 5 | 3.62 % | 0 | 0.00 % | link |
PRNP-201 | P04156 | PRNP | Major prion protein | chr20 | 30401430 | 23 | 111 | Not Cancer Driver | No | 8 | 27.59 % | 3 | 15.79 % | link |
RBM14-201 | Q96PK6 | RBM14 | RNA-binding protein 14 | chr11 | 26283796 | 350 | 669 | Not Cancer Driver | No | 1 | 2.70 % | 0 | 0.00 % | link |
SFPQ-201 | P23246 | SFPQ | Splicing factor, proline- and glutamine-rich | chr1 | 29932899 | 1 | 707 | Census | Yes | 37 | 100.00 % | 0 | 0.00 % | link |
SOS1-202 | Q07889 | SOS1 | Son of sevenless homolog 1 | chr2 | 27056844 | 1117 | 1319 | Compendium | Yes | 20 | 12.90 % | 0 | 0.00 % | link |
SPOP-206 | O43791 | SPOP | Speckle-type POZ protein | chr17 | 30244836 | 28 | 359 | Census, Compendium | Yes | 133 | 97.79 % | 5 | 83.33 % | link |
SQSTM1-202 | Q13501 | SQSTM1 | Sequestosome-1 | chr5 | 29507397 | 3 | 102 | Not Cancer Driver | No | 6 | 14.63 % | 4 | 13.33 % | link |
SQSTM1-202 | Q13501 | SQSTM1 | Sequestosome-1 | chr5 | 29507397 | 389 | 440 | Not Cancer Driver | No | 4 | 9.76 % | 9 | 30.00 % | link |
SYN1-201 | P17600 | SYN1 | Synapsin-1 | chrX | 29976799 | 421 | 705 | Not Cancer Driver | No | 13 | 24.53 % | 0 | 0.00 % | link |
SYN2-206 | Q92777 | SYN2 | Synapsin-2 | chr3 | 29976799 | 421 | 582 | Not Cancer Driver | No | 0 | 0.00 % | 0 | 0.00 % | link |
TAF15-214 | Q92804 | TAF15 | TATA-binding protein-associated factor 2N | chr17 | 26286827 | 1 | 180 | Census, Compendium | Yes | 11 | 36.67 % | 0 | 0.00 % | link |
TAF15-214 | Q92804 | TAF15 | TATA-binding protein-associated factor 2N | chr17 | 26286827 | 181 | 216 | Census, Compendium | Yes | 4 | 13.33 % | 0 | 0.00 % | link |
TAF15-214 | Q92804 | TAF15 | TATA-binding protein-associated factor 2N | chr17 | 26286827 | 234 | 320 | Census, Compendium | Yes | 8 | 26.67 % | 0 | 0.00 % | link |
TARDBP-201 | Q13148 | TARDBP | TAR DNA-binding protein 43 | chr1 | 29555476 | 1 | 102 | Not Cancer Driver | No | 7 | 19.44 % | 0 | 0.00 % | link |
TARDBP-201 | Q13148 | TARDBP | TAR DNA-binding protein 43 | chr1 | 29555476 | 263 | 414 | Not Cancer Driver | No | 14 | 38.89 % | 20 | 95.24 % | link |
TIA1-205 | P31483 | TIA1 | Cytotoxic granule associated RNA binding protein TIA1 | chr2 | 29298433 | 1 | 386 | Not Cancer Driver | No | 28 | 100.00 % | 2 | 100.00 % | link |
TNRC6B-206 | Q9UPQ9 | TNRC6B | Trinucleotide repeat-containing gene 6B protein | chr22 | 29576456 | 437 | 1056 | Not Cancer Driver | No | 52 | 34.90 % | 0 | 0.00 % | link |
TP53BP1-201 | Q12888 | TP53BP1 | TP53-binding protein 1 | chr15 | 31267591 | 1203 | 1972 | Not Cancer Driver | No | 63 | 39.62 % | 0 | 0.00 % | link |
U2AF2-201 | P26368 | U2AF2 | Splicing factor U2AF 65 kDa subunit | chr19 | 31271494 | 27 | 62 | Compendium | Yes | 2 | 3.03 % | 0 | 0.00 % | link |
U2AF2-201 | P26368 | U2AF2 | Splicing factor U2AF 65 kDa subunit | chr19 | 31271494 | 149 | 337 | Compendium | Yes | 32 | 48.48 % | 0 | 0.00 % | link |
U2AF2-201 | P26368 | U2AF2 | Splicing factor U2AF 65 kDa subunit | chr19 | 31271494 | 385 | 466 | Compendium | Yes | 10 | 15.15 % | 0 | 0.00 % | link |
UBQLN2-201 | Q9UHD9 | UBQLN2 | Ubiquilin-2 | chrX | 29526694 | 450 | 624 | Not Cancer Driver | No | 0 | 0.00 % | 5 | 62.50 % | link |
WASL-201 | O00401 | WASL | Actin nucleation-promoting factor WASL | chr7 | 26553976 | 277 | 392 | Not Cancer Driver | No | 0 | 0.00 % | 0 | 0.00 % | link |
YTHDF1-202 | Q9BYJ9 | YTHDF1 | YTH domain-containing family protein 1 | chr20 | 31388144 | 1 | 388 | Not Cancer Driver | No | 42 | 62.69 % | 0 | 0.00 % | link |
YTHDF1-202 | Q9BYJ9 | YTHDF1 | YTH domain-containing family protein 1 | chr20 | 31388144 | 389 | 523 | Not Cancer Driver | No | 19 | 28.36 % | 0 | 0.00 % | link |
YTHDF2-201 | Q9Y5A9 | YTHDF2 | YTH domain-containing family protein 2 | chr1 | 31292544 | 1 | 409 | Not Cancer Driver | No | 28 | 58.33 % | 0 | 0.00 % | link |
YTHDF2-201 | Q9Y5A9 | YTHDF2 | YTH domain-containing family protein 2 | chr1 | 31292544 | 410 | 544 | Not Cancer Driver | No | 17 | 35.42 % | 0 | 0.00 % | link |
YTHDF3-205 | Q7Z739 | YTHDF3 | YTH domain-containing family protein 3 | chr8 | 31388144 | 1 | 415 | Not Cancer Driver | No | 40 | 70.18 % | 0 | 0.00 % | link |
YTHDF3-205 | Q7Z739 | YTHDF3 | YTH domain-containing family protein 3 | chr8 | 31388144 | 416 | 550 | Not Cancer Driver | No | 16 | 28.07 % | 0 | 0.00 % | link |
ZFP36L1-202 | Q07352 | ZFP36L1 | mRNA decay activator protein ZFP36L1 | chr14 | 30449617 | 1 | 338 | Compendium | Yes | 50 | 100.00 % | 0 | 0.00 % | link |