| GO term | GO name | GO namespace | GO def |
| GO:0016553 | base conversion or substitution editing | biological_process | Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s). [PMID:11092837] |
| GO:0031054 | pre-miRNA processing | biological_process | A process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule. [GOC:sl, PMID:15211354] |
| GO:0070922 | RISC complex assembly | biological_process | The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing completent complex that mediates gene silencing by small RNA. [PMID:14512631, PMID:14744438, PMID:19239886, PMID:22233755, PMID:27184117] |
| GO:0003677 | DNA binding | molecular_function | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb, GOC:vw] |
| GO:0003723 | RNA binding | molecular_function | Binding to an RNA molecule or a portion thereof. [GOC:jl, GOC:mah] |
| GO:0003726 | double-stranded RNA adenosine deaminase activity | molecular_function | Catalysis of the reaction |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
| GO:0001649 | osteoblast differentiation | biological_process | The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone. [CL:0000062, GO_REF:0000034, GOC:jid] |
| GO:0002244 | hematopoietic progenitor cell differentiation | biological_process | The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. [GOC:add, GOC:rl, ISBN:0781735149, PMID:16551251] |
| GO:0002566 | somatic diversification of immune receptors via somatic mutation | biological_process | The process in which immune receptor genes are diversified through somatic mutation. [ISBN:0781735149, PMID:16102575] |
| GO:0006382 | adenosine to inosine editing | biological_process | The conversion of an adenosine residue to inosine in an RNA molecule by deamination. [PMID:11092837] |
| GO:0006397 | mRNA processing | biological_process | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. [GOC:mah] |
| GO:0009615 | response to virus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. [GOC:hb] |
| GO:0030218 | erythrocyte differentiation | biological_process | The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. [GOC:mah] |
| GO:0035455 | response to interferon-alpha | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon. [GOC:sl, PMID:11356686] |
| GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation | biological_process | The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase. [GOC:jl] |
| GO:0045070 | positive regulation of viral genome replication | biological_process | Any process that activates or increases the frequency, rate or extent of viral genome replication. [GOC:ai] |
| GO:0045087 | innate immune response | biological_process | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu] |
| GO:0051607 | defense response to virus | biological_process | Reactions triggered in response to the presence of a virus that act to protect the cell or organism. [GOC:ai] |
| GO:0060216 | definitive hemopoiesis | biological_process | A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood. [GOC:bf, GOC:dph, PMID:15378083, PMID:15617691] |
| GO:0060339 | negative regulation of type I interferon-mediated signaling pathway | biological_process | Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. [GOC:dph] |
| GO:0061484 | hematopoietic stem cell homeostasis | biological_process | Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. [GOC:dph, PMID:21508411] |
| GO:0097284 | hepatocyte apoptotic process | biological_process | Any apoptotic process in a hepatocyte, the main structural component of the liver. [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020] |
| GO:0098586 | cellular response to virus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. [GOC:dos] |
| GO:1900369 | negative regulation of post-transcriptional gene silencing by regulatory ncRNA | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of post-transcriptional gene silencing by RNA. [GOC:kmv, GOC:TermGenie, PMID:22412382] |
| GO:1903944 | negative regulation of hepatocyte apoptotic process | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process. [GO_REF:0000058, GOC:TermGenie, PMID:8649852] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0005730 | nucleolus | cellular_component | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. [ISBN:0198506732] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| GO:0044530 | supraspliceosomal complex | cellular_component | Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing. [GOC:ans, GOC:jl, PMID:19282290] |
| GO:0008251 | tRNA-specific adenosine deaminase activity | molecular_function | Catalysis of the reaction |
| GO:0003725 | double-stranded RNA binding | molecular_function | Binding to double-stranded RNA. [GOC:jl] |
| GO:0006396 | RNA processing | biological_process | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. [GOC:mah] |