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ADCY10-202 ,ADCY10 ,Q96PN6
  • Uniprot Accession= Q96PN6
  • Ensembl Transcript= ENST00000367851.9
  • Uniprot Name= ADCY10
  • Name= Adenylate cyclase type 10
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 47
GO term GO name GO namespace GO def
GO:0015630 microtubule cytoskeleton cellular_component The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. [GOC:jl, ISBN:0395825172]
GO:0031514 motile cilium cellular_component A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. [GOC:cilia, GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998, PMID:22118931]
GO:0000287 magnesium ion binding molecular_function Binding to a magnesium (Mg) ion. [GOC:ai]
GO:0004016 adenylate cyclase activity molecular_function Catalysis of the reaction
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0030145 manganese ion binding molecular_function Binding to a manganese ion (Mn). [GOC:ai]
GO:0051117 ATPase binding molecular_function Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP. [GOC:ai]
GO:0071890 bicarbonate binding molecular_function Binding to bicarbonate ions (CHO3-). [GOC:curators]
GO:0003351 epithelial cilium movement involved in extracellular fluid movement biological_process The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid. [GOC:dph, GOC:krc]
GO:0006007 glucose catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. [GOC:ai]
GO:0006171 cAMP biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). [ISBN:0198506732]
GO:0007286 spermatid development biological_process The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. [GOC:dph, GOC:go_curators]
GO:0010613 positive regulation of cardiac muscle hypertrophy biological_process Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. [GOC:BHF, GOC:dph, GOC:tb]
GO:0010666 positive regulation of cardiac muscle cell apoptotic process biological_process Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
GO:0010800 positive regulation of peptidyl-threonine phosphorylation biological_process Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. [GOC:dph, GOC:tb]
GO:0010917 negative regulation of mitochondrial membrane potential biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. [GOC:dph, GOC:tb]
GO:0035556 intracellular signal transduction biological_process The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782]
GO:0045773 positive regulation of axon extension biological_process Any process that activates or increases the frequency, rate or extent of axon extension. [GOC:go_curators]
GO:0045778 positive regulation of ossification biological_process Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. [GOC:go_curators]
GO:0045819 positive regulation of glycogen catabolic process biological_process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. [GOC:go_curators]
GO:0051901 positive regulation of mitochondrial depolarization biological_process Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. [GOC:ai]
GO:0060306 regulation of membrane repolarization biological_process Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative. [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb]
GO:0071241 cellular response to inorganic substance biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. [GOC:mah]
GO:0106028 neuron projection retraction biological_process The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. [GOC:aruk, GOC:bc, PMID:11585923]
GO:0106135 negative regulation of cardiac muscle cell contraction biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction. [PMID:19525381]
GO:1901524 regulation of mitophagy biological_process Any process that modulates the frequency, rate or extent of macromitophagy. [GOC:TermGenie]
GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway biological_process Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie]
GO:1903427 negative regulation of reactive oxygen species biosynthetic process biological_process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804]
GO:1903428 positive regulation of reactive oxygen species biosynthetic process biological_process Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24252804]
GO:1903955 positive regulation of protein targeting to mitochondrion biological_process Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24270810]
GO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process biological_process Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107]
GO:1990138 neuron projection extension biological_process Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. [GOC:BHF, GOC:rl, PMID:22790009]
GO:1990535 neuron projection maintenance biological_process The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. [GOC:kmv, PMID:25359212]
GO:1990544 mitochondrial ATP transmembrane transport biological_process The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion. [PMID:18485069]
GO:2001171 positive regulation of ATP biosynthetic process biological_process Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process. [GOC:obol]
GO:0005576 extracellular region cellular_component The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005739 mitochondrion cellular_component A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0016324 apical plasma membrane cellular_component The region of the plasma membrane located at the apical end of the cell. [GOC:curators]
GO:0030425 dendrite cellular_component A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. [GOC:aruk, GOC:bc, GOC:dos, GOC:mah, GOC:nln, ISBN:0198506732]
GO:0043025 neuronal cell body cellular_component The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. [GOC:go_curators]
GO:0045178 basal part of cell cellular_component The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue. [GOC:mah, ISBN:0815316194]
GO:0048471 perinuclear region of cytoplasm cellular_component Cytoplasm situated near, or occurring around, the nucleus. [GOC:jid]
GO:0090724 central region of growth cone cellular_component The center of the migrating motile tip of a growing nerve cell axon or dendrite. [GOC:sl, PMID:16260607]
GO:0097450 astrocyte end-foot cellular_component Terminal process of astrocyte abutting non-neuronal surfaces in the brain. [NIF_Subcellular:sao388182739]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]