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AK4-201 ,AK4 ,P27144
  • Uniprot Accession= P27144
  • Ensembl Transcript= ENST00000327299.8
  • Uniprot Name= AK4
  • Name= Adenylate kinase 4, mitochondrial
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 21
GO term GO name GO namespace GO def
GO:0004017 adenylate kinase activity molecular_function Catalysis of the reaction
GO:0046899 nucleoside triphosphate adenylate kinase activity molecular_function Catalysis of the reaction
GO:0071456 cellular response to hypoxia biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. [GOC:mah]
GO:0004550 nucleoside diphosphate kinase activity molecular_function Catalysis of the reaction
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0005525 GTP binding molecular_function Binding to GTP, guanosine triphosphate. [GOC:ai]
GO:0050145 nucleoside monophosphate kinase activity molecular_function Catalysis of the reaction
GO:0002082 regulation of oxidative phosphorylation biological_process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. [GOC:dph]
GO:0006172 ADP biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate. [GOC:ai]
GO:0009188 ribonucleoside diphosphate biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]
GO:0015949 nucleobase-containing small molecule interconversion biological_process The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule. [GOC:mah, ISBN:0306444747, ISBN:0471394831]
GO:0016310 phosphorylation biological_process The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. [ISBN:0198506732]
GO:0046033 AMP metabolic process biological_process The chemical reactions and pathways involving AMP, adenosine monophosphate. [GOC:go_curators]
GO:0046034 ATP metabolic process biological_process The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator. [GOC:go_curators]
GO:0046039 GTP metabolic process biological_process The chemical reactions and pathways involving GTP, guanosine triphosphate. [GOC:go_curators]
GO:0046940 nucleoside monophosphate phosphorylation biological_process The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside. [GOC:ai]
GO:0005739 mitochondrion cellular_component A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732]
GO:0005759 mitochondrial matrix cellular_component The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. [GOC:as, ISBN:0198506732]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0009142 nucleoside triphosphate biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]