Filter in search result
Please select a valid state.
AKT3-217 ,AKT3 ,Q9Y243
  • Uniprot Accession= Q9Y243
  • Ensembl Transcript= ENST00000673466.1
  • Uniprot Name= AKT3
  • Name= RAC-gamma serine/threonine-protein kinase
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of GO Term: 24
GO term GO name GO namespace GO def
GO:0004672 protein kinase activity molecular_function Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction
GO:0004674 protein serine/threonine kinase activity molecular_function Catalysis of the reactions
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0106310 protein serine kinase activity molecular_function Catalysis of the reactions
GO:0000002 mitochondrial genome maintenance biological_process The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome. [GOC:ai, GOC:vw]
GO:0001938 positive regulation of endothelial cell proliferation biological_process Any process that activates or increases the rate or extent of endothelial cell proliferation. [GOC:add]
GO:0006468 protein phosphorylation biological_process The process of introducing a phosphate group on to a protein. [GOC:hb]
GO:0007165 signal transduction biological_process The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. [GOC:go_curators, GOC:mtg_signaling_feb11]
GO:0032008 positive regulation of TOR signaling biological_process Any process that activates or increases the frequency, rate or extent of TOR signaling. [GOC:mah]
GO:0043536 positive regulation of blood vessel endothelial cell migration biological_process Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. [GOC:go_curators]
GO:0045766 positive regulation of angiogenesis biological_process Any process that activates or increases angiogenesis. [GOC:go_curators]
GO:0045793 positive regulation of cell size biological_process Any process that increases cell size. [GOC:go_curators]
GO:0048854 brain morphogenesis biological_process The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). [GOC:dgh, GOC:jid]
GO:0048873 homeostasis of number of cells within a tissue biological_process Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue. [GOC:isa_complete]
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis biological_process Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]
GO:1905564 positive regulation of vascular endothelial cell proliferation biological_process Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation. [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774]
GO:1905653 positive regulation of artery morphogenesis biological_process Any process that activates or increases the frequency, rate or extent of artery morphogenesis. [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411]
GO:2000773 negative regulation of cellular senescence biological_process Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. [GOC:BHF]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0035556 intracellular signal transduction biological_process The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782]
GO:0018105 peptidyl-serine phosphorylation biological_process The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. [RESID:AA0037]