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APCS-201 ,APCS ,P02743
  • Uniprot Accession= P02743
  • Ensembl Transcript= ENST00000255040.3
  • Uniprot Name= APCS
  • Name= Serum amyloid P-component
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 26
GO term GO name GO namespace GO def
GO:0062023 collagen-containing extracellular matrix cellular_component An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. [GOC:BHF, GOC:rph, PMID:21123617]
GO:0001849 complement component C1q complex binding molecular_function Binding to a C1q complex, a component of the classical complement cascade. [GOC:add, ISBN:0781735149]
GO:0005509 calcium ion binding molecular_function Binding to a calcium ion (Ca2+). [GOC:ai]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0030246 carbohydrate binding molecular_function Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0046790 virion binding molecular_function Binding to a virion, either by binding to components of the capsid or the viral envelope. [GOC:ai]
GO:0051082 unfolded protein binding molecular_function Binding to an unfolded protein. [GOC:ai]
GO:0002674 negative regulation of acute inflammatory response biological_process Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response. [GOC:add]
GO:0006457 protein folding biological_process The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. [GOC:go_curators, GOC:rb]
GO:0006953 acute-phase response biological_process An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals. [ISBN:0198506732]
GO:0044869 negative regulation by host of viral exo-alpha-sialidase activity biological_process The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. [GOC:jl]
GO:0044871 negative regulation by host of viral glycoprotein metabolic process biological_process A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process. [GOC:jl]
GO:0045087 innate immune response biological_process Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu]
GO:0045656 negative regulation of monocyte differentiation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation. [GOC:go_curators]
GO:0046597 negative regulation of viral entry into host cell biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell. [GOC:jl]
GO:0048525 negative regulation of viral process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant. [GOC:bf, GOC:jl]
GO:0051131 chaperone-mediated protein complex assembly biological_process The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. [GOC:ai]
GO:0061045 negative regulation of wound healing biological_process Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. [GOC:dph]
GO:1903016 negative regulation of exo-alpha-sialidase activity biological_process Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity. [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079]
GO:1903019 negative regulation of glycoprotein metabolic process biological_process Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079]
GO:0005576 extracellular region cellular_component The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
GO:0005615 extracellular space cellular_component That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0070062 extracellular exosome cellular_component A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]
GO:0072562 blood microparticle cellular_component A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids. [GOC:BHF, GOC:mah, PMID:16373184]