| GO term | GO name | GO namespace | GO def |
| GO:0005391 | P-type sodium:potassium-exchanging transporter activity | molecular_function | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0005524 | ATP binding | molecular_function | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732] |
| GO:0016791 | phosphatase activity | molecular_function | Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. [GOC:curators, GOC:pg] |
| GO:0016887 | ATP hydrolysis activity | molecular_function | Catalysis of the reaction |
| GO:0030955 | potassium ion binding | molecular_function | Binding to a potassium ion (K+). [GOC:mah] |
| GO:0031402 | sodium ion binding | molecular_function | Binding to a sodium ion (Na+). [GOC:mah] |
| GO:0046982 | protein heterodimerization activity | molecular_function | Binding to a nonidentical protein to form a heterodimer. [GOC:ai] |
| GO:0051087 | protein-folding chaperone binding | molecular_function | Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport. [PMID:10585443] |
| GO:1990239 | steroid hormone binding | molecular_function | Binding to a steroid hormone. [GOC:ln] |
| GO:0002026 | regulation of the force of heart contraction | biological_process | Any process that modulates the extent of heart contraction, changing the force with which blood is propelled. [GOC:dph, GOC:tb, PMID:10358008] |
| GO:0002028 | regulation of sodium ion transport | biological_process | Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph] |
| GO:0006883 | intracellular sodium ion homeostasis | biological_process | A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell. [GOC:ai, GOC:mah] |
| GO:0008217 | regulation of blood pressure | biological_process | Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. [GOC:dph, GOC:mtg_cardio, ISBN:0721643949] |
| GO:0009410 | response to xenobiotic stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:jl, GOC:krc] |
| GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient | biological_process | The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore. [GOC:mah, GOC:sm] |
| GO:0030007 | intracellular potassium ion homeostasis | biological_process | A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell. [GOC:mah] |
| GO:0031947 | negative regulation of glucocorticoid biosynthetic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. [GOC:mah] |
| GO:0036376 | sodium ion export across plasma membrane | biological_process | The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region. [GOC:vw, PMID:14674689] |
| GO:0045822 | negative regulation of heart contraction | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. [GOC:go_curators] |
| GO:0045823 | positive regulation of heart contraction | biological_process | Any process that activates or increases the frequency, rate or extent of heart contraction. [GOC:go_curators] |
| GO:0045989 | positive regulation of striated muscle contraction | biological_process | Any process that activates or increases the frequency, rate or extent of striated muscle contraction. [GOC:go_curators] |
| GO:0055119 | relaxation of cardiac muscle | biological_process | The process in which the extent of cardiac muscle contraction is reduced. [GOC:ecd] |
| GO:0071383 | cellular response to steroid hormone stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. [GOC:mah] |
| GO:0086002 | cardiac muscle cell action potential involved in contraction | biological_process | An action potential that occurs in a cardiac muscle cell and is involved in its contraction. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] |
| GO:0086009 | membrane repolarization | biological_process | The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] |
| GO:0086013 | membrane repolarization during cardiac muscle cell action potential | biological_process | The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] |
| GO:0086064 | cell communication by electrical coupling involved in cardiac conduction | biological_process | The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] |
| GO:1902600 | proton transmembrane transport | biological_process | The directed movement of a proton across a membrane. [GO_REF:0000069, GOC:pr, GOC:TermGenie] |
| GO:1903416 | response to glycoside | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus. [GO_REF:0000071, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:12027881, PMID:16243970] |
| GO:1990573 | potassium ion import across plasma membrane | biological_process | The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol. [PMID:9139127] |
| GO:0005783 | endoplasmic reticulum | cellular_component | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732] |
| GO:0005794 | Golgi apparatus | cellular_component | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. [ISBN:0198506732] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| GO:0005890 | sodium:potassium-exchanging ATPase complex | cellular_component | Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior. [ISBN:0198506732] |
| GO:0014069 | postsynaptic density | cellular_component | An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. [GOC:BHF, GOC:dos, GOC:ef, GOC:jid, GOC:pr, GOC:sjp, http://molneuro.kaist.ac.kr/psd, PMID:14532281, Wikipedia:Postsynaptic_density] |
| GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| GO:0016323 | basolateral plasma membrane | cellular_component | The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators] |
| GO:0016324 | apical plasma membrane | cellular_component | The region of the plasma membrane located at the apical end of the cell. [GOC:curators] |
| GO:0016328 | lateral plasma membrane | cellular_component | The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells. [GOC:hb, GOC:mah, GOC:pr] |
| GO:0030315 | T-tubule | cellular_component | Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane. [GOC:mtg_muscle, ISBN:0815316194] |
| GO:0030424 | axon | cellular_component | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. [GOC:nln, ISBN:0198506732] |
| GO:0031090 | organelle membrane | cellular_component | A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. [GOC:dos, GOC:mah] |
| GO:0036126 | sperm flagellum | cellular_component | A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid. [GOC:cilia, GOC:sart, PMID:8441407] |
| GO:0042383 | sarcolemma | cellular_component | The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers. [ISBN:0198506732] |
| GO:0042470 | melanosome | cellular_component | A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. [GOC:jl, PMID:11584301] |
| GO:0045121 | membrane raft | cellular_component | Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. [PMID:16645198, PMID:20044567] |
| GO:0060342 | photoreceptor inner segment membrane | cellular_component | The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. [GOC:dph] |
| GO:0070062 | extracellular exosome | cellular_component | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] |
| GO:1903561 | extracellular vesicle | cellular_component | Any vesicle that is part of the extracellular region. [GO_REF:0000064, GOC:pm, GOC:TermGenie, PMID:24769233] |
| GO:0032991 | protein-containing complex | cellular_component | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah] |