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ATP6V0B-205 ,ATP6V0B ,Q99437
  • Uniprot Accession= Q99437
  • Ensembl Transcript= ENST00000472174.7
  • Uniprot Name= ATP6V0B
  • Name= V-type proton ATPase 21 kDa proteolipid subunit c''
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 19
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0046961 proton-transporting ATPase activity, rotational mechanism molecular_function Enables the transfer of protons from one side of a membrane to the other according to the reaction
GO:0007035 vacuolar acidification biological_process Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion. [GOC:jid]
GO:0007042 lysosomal lumen acidification biological_process Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. [GOC:jid]
GO:0016241 regulation of macroautophagy biological_process Any process that modulates the frequency, rate or extent of macroautophagy. [GOC:krc]
GO:0048388 endosomal lumen acidification biological_process Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion. [GOC:jid]
GO:0051452 intracellular pH reduction biological_process Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion. [GOC:ai]
GO:0061795 Golgi lumen acidification biological_process Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion. [GOC:dph, PMID:23447592]
GO:1902600 proton transmembrane transport biological_process The directed movement of a proton across a membrane. [GO_REF:0000069, GOC:pr, GOC:TermGenie]
GO:0000139 Golgi membrane cellular_component The lipid bilayer surrounding any of the compartments of the Golgi apparatus. [GOC:mah]
GO:0005765 lysosomal membrane cellular_component The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0010008 endosome membrane cellular_component The lipid bilayer surrounding an endosome. [GOC:mah]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0030665 clathrin-coated vesicle membrane cellular_component The lipid bilayer surrounding a clathrin-coated vesicle. [GOC:mah]
GO:0030670 phagocytic vesicle membrane cellular_component The lipid bilayer surrounding a phagocytic vesicle. [GOC:mah]
GO:0033176 proton-transporting V-type ATPase complex cellular_component A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane. [GOC:mah, ISBN:0716743663, PMID:16449553]
GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain cellular_component The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. [GOC:mah, PMID:16449553]
GO:1902495 transmembrane transporter complex cellular_component A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. [GOC:bhm, GOC:TermGenie, PMID:18024586]