GO term | GO name | GO namespace | GO def |
GO:0001618 | virus receptor activity | molecular_function | Combining with a virus component and mediating entry of the virus into the cell. [GOC:bf, GOC:dph, PMID:7621403, UniProtKB-KW:KW-1183] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0038023 | signaling receptor activity | molecular_function | Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. [GOC:bf, GOC:signaling] |
GO:0045296 | cadherin binding | molecular_function | Binding to cadherin, a type I membrane protein involved in cell adhesion. [GOC:bf] |
GO:0002250 | adaptive immune response | biological_process | An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). [GO_REF:0000022, GOC:add, ISBN:0781735149] |
GO:0002456 | T cell mediated immunity | biological_process | Any process involved in the carrying out of an immune response by a T cell. [GO_REF:0000022, GOC:add, ISBN:0781735149] |
GO:0006958 | complement activation, classical pathway | biological_process | Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes. [GOC:add, ISBN:0781735149] |
GO:0007338 | single fertilization | biological_process | The union of male and female gametes to form a zygote. [GOC:ems, GOC:mtg_sensu] |
GO:0008593 | regulation of Notch signaling pathway | biological_process | Any process that modulates the frequency, rate or extent of the Notch signaling pathway. [GOC:go_curators] |
GO:0010628 | positive regulation of gene expression | biological_process | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
GO:0010629 | negative regulation of gene expression | biological_process | Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
GO:0032733 | positive regulation of interleukin-10 production | biological_process | Any process that activates or increases the frequency, rate, or extent of interleukin-10 production. [GOC:mah] |
GO:0035581 | sequestering of extracellular ligand from receptor | biological_process | The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor. [GOC:BHF, GOC:signaling] |
GO:0042102 | positive regulation of T cell proliferation | biological_process | Any process that activates or increases the rate or extent of T cell proliferation. [GOC:ai] |
GO:0043382 | positive regulation of memory T cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of memory T cell differentiation. [ISBN:0781735149] |
GO:0045087 | innate immune response | biological_process | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu] |
GO:0045591 | positive regulation of regulatory T cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells. [ISBN:0781735149] |
GO:0046718 | symbiont entry into host cell | biological_process | The process by which a symbiont breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the symbiont or its genome is released into the host cell. [GOC:jl] |
GO:0071636 | positive regulation of transforming growth factor beta production | biological_process | Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta. [GOC:mah] |
GO:0002079 | inner acrosomal membrane | cellular_component | The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane. [GOC:dph, PMID:3899643, PMID:8936405] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0005925 | focal adhesion | cellular_component | A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). [GOC:aruk, GOC:bc, ISBN:0124325653, ISBN:0815316208, PMID:10419689, PMID:12191915, PMID:15246682, PMID:1643657, PMID:16805308, PMID:19197329, PMID:23033047, PMID:26923917, PMID:28796323, PMID:8314002] |
GO:0009986 | cell surface | cellular_component | The external part of the cell wall and/or plasma membrane. [GOC:jl, GOC:mtg_sensu, GOC:sm] |
GO:0070062 | extracellular exosome | cellular_component | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] |
GO:0045959 | negative regulation of complement activation, classical pathway | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway. [GOC:go_curators] |
GO:0005615 | extracellular space | cellular_component | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684] |