| GO term | GO name | GO namespace | GO def |
| GO:0000993 | RNA polymerase II complex binding | molecular_function | Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits. [GOC:txnOH] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH] |
| GO:0001558 | regulation of cell growth | biological_process | Any process that modulates the frequency, rate, extent or direction of cell growth. [GOC:go_curators] |
| GO:0001711 | endodermal cell fate commitment | biological_process | The cell differentiation process that results in commitment of a cell to become part of the endoderm. [GOC:go_curators, ISBN:0878932437] |
| GO:0006368 | transcription elongation by RNA polymerase II | biological_process | The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II. [GOC:mah, GOC:txnOH] |
| GO:0007049 | cell cycle | biological_process | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. [GOC:go_curators, GOC:mtg_cell_cycle] |
| GO:0008285 | negative regulation of cell population proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of cell proliferation. [GOC:go_curators] |
| GO:0016055 | Wnt signaling pathway | biological_process | The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a target cell and ending with a change in cell state. [PMID:11532397] |
| GO:0019827 | stem cell population maintenance | biological_process | The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms |
| GO:0030177 | positive regulation of Wnt signaling pathway | biological_process | Any process that activates or increases the frequency, rate or extent of Wnt signal transduction. [GOC:dph, GOC:go_curators, GOC:tb] |
| GO:0031124 | mRNA 3'-end processing | biological_process | Any process involved in forming the mature 3' end of an mRNA molecule. [GOC:mah] |
| GO:0031442 | positive regulation of mRNA 3'-end processing | biological_process | Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing. [GOC:mah] |
| GO:0031648 | protein destabilization | biological_process | Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. [GOC:mah] |
| GO:0043066 | negative regulation of apoptotic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis] |
| GO:0045638 | negative regulation of myeloid cell differentiation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. [GOC:go_curators] |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. [GOC:go_curators, GOC:txnOH] |
| GO:0048147 | negative regulation of fibroblast proliferation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. [GOC:jid] |
| GO:0050680 | negative regulation of epithelial cell proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. [GOC:ai] |
| GO:0071222 | cellular response to lipopolysaccharide | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. [GOC:mah] |
| GO:1902808 | positive regulation of cell cycle G1/S phase transition | biological_process | Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle. [GO_REF:0000058, GOC:mtg_cell_cycle, GOC:TermGenie] |
| GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | biological_process | Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. [GOC:mtg_cell_cycle] |
| GO:0000781 | chromosome, telomeric region | cellular_component | The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). [GOC:elh] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0016593 | Cdc73/Paf1 complex | cellular_component | A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p. [PMID:11884586] |
| GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex | biological_process | The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript. [PMID:18195044] |
| GO:0032968 | positive regulation of transcription elongation by RNA polymerase II | biological_process | Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. [GOC:mah, GOC:txnOH] |