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CDKN2C-202 ,CDKN2C ,P42773
  • Uniprot Accession= P42773
  • Ensembl Transcript= ENST00000371761.4
  • Uniprot Name= CDKN2C
  • Name= Cyclin-dependent kinase 4 inhibitor C
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of GO Term: 15
GO term GO name GO namespace GO def
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity molecular_function Binds to and stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase. [GOC:mah, GOC:pr]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0019901 protein kinase binding molecular_function Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. [GOC:jl]
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity biological_process Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity. [GOC:go_curators, GOC:pr]
GO:0007049 cell cycle biological_process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. [GOC:go_curators, GOC:mtg_cell_cycle]
GO:0008285 negative regulation of cell population proliferation biological_process Any process that stops, prevents or reduces the rate or extent of cell proliferation. [GOC:go_curators]
GO:0030308 negative regulation of cell growth biological_process Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. [GOC:go_curators]
GO:0042326 negative regulation of phosphorylation biological_process Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. [GOC:jl]
GO:0048709 oligodendrocyte differentiation biological_process The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. [GOC:vp, PMID:15139015]
GO:0072089 stem cell proliferation biological_process The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. [GOC:mtg_kidney_jan10]
GO:2000045 regulation of G1/S transition of mitotic cell cycle biological_process Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. [GOC:mtg_cell_cycle]
GO:2000647 negative regulation of stem cell proliferation biological_process Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation. [GOC:dph]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]