GO term | GO name | GO namespace | GO def |
GO:0030449 | regulation of complement activation | biological_process | Any process that modulates the frequency, rate or extent of complement activation. [GOC:go_curators] |
GO:1903659 | regulation of complement-dependent cytotoxicity | biological_process | Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity. [GO_REF:0000058, GOC:TermGenie, PMID:24280217] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0008201 | heparin binding | molecular_function | Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. [GOC:jl, ISBN:0198506732] |
GO:0042802 | identical protein binding | molecular_function | Binding to an identical protein or proteins. [GOC:jl] |
GO:0043395 | heparan sulfate proteoglycan binding | molecular_function | Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit. [ISBN:0198506732] |
GO:0006508 | proteolysis | biological_process | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah] |
GO:0006956 | complement activation | biological_process | Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. [GO_REF:0000022, GOC:add, ISBN:0781735149] |
GO:0006957 | complement activation, alternative pathway | biological_process | Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. [GOC:add, ISBN:0781735149] |
GO:0030451 | regulation of complement activation, alternative pathway | biological_process | Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation. [GOC:go_curators] |
GO:0005576 | extracellular region | cellular_component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
GO:0005615 | extracellular space | cellular_component | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684] |
GO:0070062 | extracellular exosome | cellular_component | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] |
GO:0072562 | blood microparticle | cellular_component | A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids. [GOC:BHF, GOC:mah, PMID:16373184] |
GO:0106139 | symbiont cell surface | cellular_component | The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. [GOC:rjd, PMID:30049880] |
GO:1905370 | serine-type endopeptidase complex | cellular_component | A protein complex which is capable of serine-type endopeptidase activity. [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:1689240] |
GO:0001851 | complement component C3b binding | molecular_function | Binding to a C3b product of the complement cascade. [GOC:add, ISBN:0781735149] |