| GO term | GO name | GO namespace | GO def |
| GO:0004222 | metalloendopeptidase activity | molecular_function | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE] |
| GO:0005254 | chloride channel activity | molecular_function | Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. [GOC:mtg_transport, GOC:pr, ISBN:0815340729] |
| GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
| GO:0006508 | proteolysis | biological_process | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah] |
| GO:0034220 | monoatomic ion transmembrane transport | biological_process | A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. [GOC:mah] |
| GO:1902476 | chloride transmembrane transport | biological_process | The process in which chloride is transported across a membrane. [GOC:TermGenie, GOC:vw] |
| GO:0005576 | extracellular region | cellular_component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| GO:0016324 | apical plasma membrane | cellular_component | The region of the plasma membrane located at the apical end of the cell. [GOC:curators] |
| GO:0005229 | intracellular calcium activated chloride channel activity | molecular_function | Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. [GOC:mtg_transport] |