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CLK2-203 ,CLK2 ,P49760
  • Uniprot Accession= P49760
  • Ensembl Transcript= ENST00000368361.9
  • Uniprot Name= CLK2
  • Name= Dual specificity protein kinase CLK2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 17
GO term GO name GO namespace GO def
GO:0004674 protein serine/threonine kinase activity molecular_function Catalysis of the reactions
GO:0004712 protein serine/threonine/tyrosine kinase activity molecular_function Catalysis of the reactions
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0106310 protein serine kinase activity molecular_function Catalysis of the reactions
GO:0006468 protein phosphorylation biological_process The process of introducing a phosphate group on to a protein. [GOC:hb]
GO:0010212 response to ionizing radiation biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. [PMID:12509526]
GO:0043484 regulation of RNA splicing biological_process Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. [GOC:jl]
GO:0045721 negative regulation of gluconeogenesis biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. [GOC:go_curators]
GO:0046777 protein autophosphorylation biological_process The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation). [ISBN:0198506732]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0016604 nuclear body cellular_component Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. [GOC:ma, PMID:10330182]
GO:0016607 nuclear speck cellular_component A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. [http://www.cellnucleus.com/]
GO:0004713 protein tyrosine kinase activity molecular_function Catalysis of the reaction
GO:0018108 peptidyl-tyrosine phosphorylation biological_process The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. [RESID:AA0039]