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CRB1-203 ,CRB1 ,P82279
  • Uniprot Accession= P82279
  • Ensembl Transcript= ENST00000367400.8
  • Uniprot Name= CRB1
  • Name= Protein crumbs homolog 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 30
GO term GO name GO namespace GO def
GO:0005509 calcium ion binding molecular_function Binding to a calcium ion (Ca2+). [GOC:ai]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0001974 blood vessel remodeling biological_process The reorganization or renovation of existing blood vessels. [GOC:hjd]
GO:0007009 plasma membrane organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. [GOC:dph, GOC:jl, GOC:mah]
GO:0007163 establishment or maintenance of cell polarity biological_process Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. [GOC:mah]
GO:0007267 cell-cell signaling biological_process Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. [GOC:dos, GOC:mah]
GO:0008104 protein localization biological_process Any process in which a protein is transported to, or maintained in, a specific location. [GOC:ai]
GO:0010001 glial cell differentiation biological_process The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. [GOC:go_curators, GOC:mtg_sensu]
GO:0010467 gene expression biological_process The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. [GOC:txnOH-2018, PMID:25934543, PMID:31580950]
GO:0010842 retina layer formation biological_process The process in which the vertebrate retina is organized into three laminae
GO:0035845 photoreceptor cell outer segment organization biological_process A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials. [ISBN:0824072820, PMID:14507858]
GO:0042462 eye photoreceptor cell development biological_process Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. [GOC:jl, ISBN:0192800981]
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity biological_process Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell. [GOC:bf, GOC:mah]
GO:0045494 photoreceptor cell maintenance biological_process Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light. [CL:0000210, GOC:bf, GOC:rl]
GO:0050908 detection of light stimulus involved in visual perception biological_process The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. [GOC:ai, GOC:dos]
GO:0060060 post-embryonic retina morphogenesis in camera-type eye biological_process The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage. [GOC:dgh, GOC:dph]
GO:0061159 establishment of bipolar cell polarity involved in cell morphogenesis biological_process The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane. [GOC:dph, GOC:vw]
GO:0071482 cellular response to light stimulus biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. [GOC:mah]
GO:0001750 photoreceptor outer segment cellular_component The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins. [GOC:cilia, GOC:krc, GOC:pde, ISBN:0824072820, PMID:19501669, PMID:26574505, PMID:6771304]
GO:0001917 photoreceptor inner segment cellular_component The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. [GOC:add, PMID:12019563]
GO:0005576 extracellular region cellular_component The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
GO:0005902 microvillus cellular_component Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. [ISBN:0815316194]
GO:0005912 adherens junction cellular_component A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. [GOC:aruk, GOC:bc, GOC:mah, ISBN:0198506732, PMID:17854762, PMID:20571587, PMID:21422226, PMID:28096264]
GO:0016324 apical plasma membrane cellular_component The region of the plasma membrane located at the apical end of the cell. [GOC:curators]
GO:0043296 apical junction complex cellular_component A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. [GOC:go_curators, GOC:kmv, PMID:12525486, PMID:15196556]
GO:0097386 glial cell projection cellular_component A prolongation or process extending from a glial cell. [GOC:mc]
GO:0032991 protein-containing complex cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah]
GO:0035003 subapical complex cellular_component The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells. [PMID:11752566, PMID:12500938]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules biological_process The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell. [ISBN:0198506732]