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CTNNBIP1-203 ,CTNNBIP1 ,Q9NSA3
  • Uniprot Accession= Q9NSA3
  • Ensembl Transcript= ENST00000377263.6
  • Uniprot Name= CTNNBIP1
  • Name= Beta-catenin-interacting protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 23
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0008013 beta-catenin binding molecular_function Binding to a catenin beta subunit. [GOC:bf]
GO:0070016 armadillo repeat domain binding molecular_function Binding to an armadillo repeat domain, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signaling and cytoskeletal regulation. [GOC:BHF, GOC:mah, GOC:vk, InterPro:IPR000225]
GO:0001658 branching involved in ureteric bud morphogenesis biological_process The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. [GOC:dph, PMID:16916378]
GO:0002528 regulation of vascular permeability involved in acute inflammatory response biological_process Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response. [GOC:jal]
GO:0009952 anterior/posterior pattern specification biological_process The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb]
GO:0016055 Wnt signaling pathway biological_process The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a target cell and ending with a change in cell state. [PMID:11532397]
GO:0031333 negative regulation of protein-containing complex assembly biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. [GOC:mah]
GO:0032091 negative regulation of protein binding biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. [GOC:mah]
GO:0043433 negative regulation of DNA-binding transcription factor activity biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. [GOC:jl]
GO:0045657 positive regulation of monocyte differentiation biological_process Any process that activates or increases the frequency, rate or extent of monocyte differentiation. [GOC:go_curators]
GO:0045669 positive regulation of osteoblast differentiation biological_process Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. [GOC:go_curators]
GO:0048662 negative regulation of smooth muscle cell proliferation biological_process Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. [CL:0000192, GOC:ebc]
GO:0060633 negative regulation of transcription initiation by RNA polymerase II biological_process Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter. [GOC:dph, GOC:tb, GOC:txnOH]
GO:0072201 negative regulation of mesenchymal cell proliferation biological_process Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. [GOC:mtg_kidney_jan10]
GO:0090090 negative regulation of canonical Wnt signaling pathway biological_process Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:dph, GOC:tb]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0030877 beta-catenin destruction complex cellular_component A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. [PMID:14600025]
GO:1990711 beta-catenin-ICAT complex cellular_component Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex. [GOC:bhm, PMID:12408824]
GO:0030178 negative regulation of Wnt signaling pathway biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway. [GOC:dph, GOC:go_curators, GOC:tb]