Filter in search result
Please select a valid state.
CYP4A11-201 ,CYP4A11 ,Q02928
  • Uniprot Accession= Q02928
  • Ensembl Transcript= ENST00000310638.9
  • Uniprot Name= CYP4A11
  • Name= Cytochrome P450 4A11
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 29
GO term GO name GO namespace GO def
GO:0004497 monooxygenase activity molecular_function Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. [ISBN:0198506732]
GO:0005506 iron ion binding molecular_function Binding to an iron (Fe) ion. [GOC:ai]
GO:0008392 arachidonic acid epoxygenase activity molecular_function Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid. [http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm, PMID:10681399, PMID:18952572]
GO:0018685 alkane 1-monooxygenase activity molecular_function Catalysis of the reaction
GO:0020037 heme binding molecular_function Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. [GOC:ai]
GO:0050051 leukotriene-B4 20-monooxygenase activity molecular_function Catalysis of the reaction
GO:0070330 aromatase activity molecular_function Catalysis of the reduction of an aliphatic ring to yield an aromatic ring. [GOC:cb]
GO:0102033 long-chain fatty acid omega-hydroxylase activity molecular_function Catalysis of the reaction
GO:0001676 long-chain fatty acid metabolic process biological_process The chemical reactions and pathways involving a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [GOC:ajp]
GO:0003091 renal water homeostasis biological_process Renal process involved in the maintenance of an internal steady state of water in the body. [GOC:mtg_cardio]
GO:0003095 pressure natriuresis biological_process The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis). [GOC:mtg_cardio]
GO:0006631 fatty acid metabolic process biological_process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. [ISBN:0198547684]
GO:0006691 leukotriene metabolic process biological_process The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. [GOC:ma]
GO:0019369 arachidonic acid metabolic process biological_process The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. [ISBN:0198506732]
GO:0019373 epoxygenase P450 pathway biological_process The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids. [GOC:mah, PMID:17979511]
GO:0031408 oxylipin biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids. [GOC:mah, PMID:11960741]
GO:0032305 positive regulation of icosanoid secretion biological_process Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell. [GOC:mah]
GO:0036101 leukotriene B4 catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. [GOC:yaf, PMID:9799565]
GO:0055078 sodium ion homeostasis biological_process Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell. [GOC:ai, GOC:jid, GOC:mah]
GO:0097267 omega-hydroxylase P450 pathway biological_process The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation. [GOC:mw, PMID:10681399]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005789 endoplasmic reticulum membrane cellular_component The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah]
GO:0016324 apical plasma membrane cellular_component The region of the plasma membrane located at the apical end of the cell. [GOC:curators]
GO:0043231 intracellular membrane-bounded organelle cellular_component Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators]
GO:0008391 arachidonic acid monooxygenase activity molecular_function Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water. [GOC:mah]
GO:0043651 linoleic acid metabolic process biological_process The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. [Wikipedia:Linoleic_Acid]
GO:0048252 lauric acid metabolic process biological_process The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources. [GOC:jid, PMID:15555597]
GO:0046456 icosanoid biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids. [ISBN:0198506732]
GO:0001822 kidney development biological_process The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. [GOC:dph, GOC:mtg_kidney_jan10, ISBN:0124020607, ISBN:0721662544]