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DENND2D-201 ,DENND2D ,Q9H6A0
  • Uniprot Accession= Q9H6A0
  • Ensembl Transcript= ENST00000357640.9
  • Uniprot Name= DENND2D
  • Name= DENN domain-containing protein 2D
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 4
GO term GO name GO namespace GO def
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. [GOC:kd, GOC:mah, PMID:23303910, PMID:27218782]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]