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DNAH14-211 ,DNAH14 ,Q0VDD8
  • Uniprot Accession= Q0VDD8
  • Ensembl Transcript= ENST00000445597.6
  • Uniprot Name= DNAH14
  • Name= Dynein axonemal heavy chain 14
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 9
GO term GO name GO namespace GO def
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0045505 dynein intermediate chain binding molecular_function Binding to an intermediate chain of the dynein complex. [GOC:bf]
GO:0051959 dynein light intermediate chain binding molecular_function Binding to a light intermediate chain of the dynein complex. [GOC:bf]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005874 microtubule cellular_component Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. [ISBN:0879693568]
GO:0097729 9+2 motile cilium cellular_component A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme). [GOC:cilia, PMID:22118931]
GO:0030286 dynein complex cellular_component Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity. [ISBN:0815316194]
GO:0060294 cilium movement involved in cell motility biological_process Movement of cilia mediated by motor proteins that contributes to the movement of a cell. [GOC:BHF, GOC:dph, GOC:tb]
GO:0008569 minus-end-directed microtubule motor activity molecular_function A motor activity that generates movement along a microtubule toward the minus end, driven by ATP hydrolysis. [GOC:mah, GOC:vw, PMID:15659646, PMID:32842864]