| GO term | GO name | GO namespace | GO def |
| GO:0003924 | GTPase activity | molecular_function | Catalysis of the reaction |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0005525 | GTP binding | molecular_function | Binding to GTP, guanosine triphosphate. [GOC:ai] |
| GO:0031798 | type 1 metabotropic glutamate receptor binding | molecular_function | Binding to a type 1 metabotropic glutamate receptor. [GOC:mah, GOC:nln] |
| GO:0031802 | type 5 metabotropic glutamate receptor binding | molecular_function | Binding to a type 5 metabotropic glutamate receptor. [GOC:mah, GOC:nln] |
| GO:0050998 | nitric-oxide synthase binding | molecular_function | Binding to nitric-oxide synthase. [GOC:ai] |
| GO:0099186 | structural constituent of postsynapse | molecular_function | The action of a molecule that contributes to the structural integrity of a postsynapse. [GOC:dos] |
| GO:0120283 | protein serine/threonine kinase binding | molecular_function | Binding to a protein serine/threonine kinase. [GOC:krc, GOC:sl, PMID:28608965] |
| GO:0006897 | endocytosis | biological_process | A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle. [GOC:mah, ISBN:0198506732, ISBN:0716731363, Wikipedia:Endocytosis] |
| GO:0007416 | synapse assembly | biological_process | The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional). [GOC:mah] |
| GO:0046847 | filopodium assembly | biological_process | The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. [GOC:dph, GOC:mah, GOC:tb, PMID:16337369, PMID:18464790] |
| GO:0051491 | positive regulation of filopodium assembly | biological_process | Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. [GOC:ai, GOC:dph, GOC:tb] |
| GO:0061002 | negative regulation of dendritic spine morphogenesis | biological_process | Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. [GOC:dph] |
| GO:0098884 | postsynaptic neurotransmitter receptor internalization | biological_process | A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle. [GOC:dos] |
| GO:0099173 | postsynapse organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse. [GOC:dos] |
| GO:1903423 | positive regulation of synaptic vesicle recycling | biological_process | Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22745285] |
| GO:0014069 | postsynaptic density | cellular_component | An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. [GOC:BHF, GOC:dos, GOC:ef, GOC:jid, GOC:pr, GOC:sjp, http://molneuro.kaist.ac.kr/psd, PMID:14532281, Wikipedia:Postsynaptic_density] |
| GO:0030424 | axon | cellular_component | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. [GOC:nln, ISBN:0198506732] |
| GO:0043083 | synaptic cleft | cellular_component | The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released. [GOC:jl, http://synapses.mcg.edu/anatomy/chemical/synapse.stm] |
| GO:0043197 | dendritic spine | cellular_component | A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity. [GOC:nln] |
| GO:0044327 | dendritic spine head | cellular_component | Distal part of the dendritic spine, that carries the post-synaptic density. [GOC:BHF, GOC:nln, GOC:rl] |
| GO:0048471 | perinuclear region of cytoplasm | cellular_component | Cytoplasm situated near, or occurring around, the nucleus. [GOC:jid] |
| GO:0070062 | extracellular exosome | cellular_component | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] |
| GO:0098793 | presynapse | cellular_component | The part of a synapse that is part of the presynaptic cell. [GOC:dos] |
| GO:0098844 | postsynaptic endocytic zone membrane | cellular_component | The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta. [PMID:17880892] |
| GO:0098978 | glutamatergic synapse | cellular_component | A synapse that uses glutamate as a neurotransmitter. [GOC:dos] |
| GO:0061828 | apical tubulobulbar complex | cellular_component | Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell. [PMID:20403871, PMID:22510523] |
| GO:0061829 | basal tubulobulbar complex | cellular_component | Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell. [PMID:20403871, PMID:22510523] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0008017 | microtubule binding | molecular_function | Binding to a microtubule, a filament composed of tubulin monomers. [GOC:krc] |
| GO:0031623 | receptor internalization | biological_process | A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. [GOC:bf, GOC:mah, GOC:signaling, PMID:15006537, PMID:19643732] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| GO:0045202 | synapse | cellular_component | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110] |
| GO:0005874 | microtubule | cellular_component | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. [ISBN:0879693568] |
| GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane | biological_process | Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle. [GOC:curators, PMID:10099709, PMID:20448150] |