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DRAXIN-201 ,DRAXIN ,Q8NBI3
  • Uniprot Accession= Q8NBI3
  • Ensembl Transcript= ENST00000294485.6
  • Uniprot Name= DRAXIN
  • Name= Draxin
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 12
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0007411 axon guidance biological_process The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues. [ISBN:0878932437]
GO:0016055 Wnt signaling pathway biological_process The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a target cell and ending with a change in cell state. [PMID:11532397]
GO:0021516 dorsal spinal cord development biological_process The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11179871]
GO:0021528 commissural neuron differentiation in spinal cord biological_process The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
GO:0021960 anterior commissure morphogenesis biological_process Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420]
GO:0030517 negative regulation of axon extension biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth. [GOC:mah]
GO:0030900 forebrain development biological_process The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=forebrain]
GO:0090090 negative regulation of canonical Wnt signaling pathway biological_process Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:dph, GOC:tb]
GO:0110088 hippocampal neuron apoptotic process biological_process Any apoptotic process that occurs in a hippocampal neuron. [GOC:sl, PMID:18940801]
GO:0110091 negative regulation of hippocampal neuron apoptotic process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. [GOC:sl, PMID:18940801]
GO:0005576 extracellular region cellular_component The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]