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DYRK3-203 ,DYRK3 ,O43781
  • Uniprot Accession= O43781
  • Ensembl Transcript= ENST00000367109.8
  • Uniprot Name= DYRK3
  • Name= Dual specificity tyrosine-phosphorylation-regulated kinase 3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 30
GO term GO name GO namespace GO def
GO:0000287 magnesium ion binding molecular_function Binding to a magnesium (Mg) ion. [GOC:ai]
GO:0004672 protein kinase activity molecular_function Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction
GO:0004674 protein serine/threonine kinase activity molecular_function Catalysis of the reactions
GO:0004712 protein serine/threonine/tyrosine kinase activity molecular_function Catalysis of the reactions
GO:0004713 protein tyrosine kinase activity molecular_function Catalysis of the reaction
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0106310 protein serine kinase activity molecular_function Catalysis of the reactions
GO:0006468 protein phosphorylation biological_process The process of introducing a phosphate group on to a protein. [GOC:hb]
GO:0007049 cell cycle biological_process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. [GOC:go_curators, GOC:mtg_cell_cycle]
GO:0030218 erythrocyte differentiation biological_process The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. [GOC:mah]
GO:0035063 nuclear speck organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized. [GOC:bf, GOC:curators]
GO:0035617 stress granule disassembly biological_process The disaggregation of a stress granule into its constituent protein and RNA parts. [GOC:BHF, PMID:19825938]
GO:0043066 negative regulation of apoptotic process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. [GOC:jl]
GO:0051301 cell division biological_process The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. [GOC:di, GOC:go_curators, GOC:pr]
GO:0080135 regulation of cellular response to stress biological_process Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:dhl]
GO:1902751 positive regulation of cell cycle G2/M phase transition biological_process Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. [GO_REF:0000058, GOC:jl, GOC:TermGenie]
GO:1903008 organelle disassembly biological_process The disaggregation of an organelle into its constituent components. [GO_REF:0000079, GOC:TermGenie]
GO:1903432 regulation of TORC1 signaling biological_process Any process that modulates the frequency, rate or extent of TORC1 signaling. [GO_REF:0000058, GOC:TermGenie]
GO:0000242 pericentriolar material cellular_component A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome. [GOC:clt, ISBN:0815316194]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0010494 cytoplasmic stress granule cellular_component A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. [GOC:ans, PMID:17284590, PMID:17601829, PMID:17967451, PMID:20368989]
GO:0016607 nuclear speck cellular_component A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. [http://www.cellnucleus.com/]
GO:0043231 intracellular membrane-bounded organelle cellular_component Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [GOC:go_curators]
GO:0005856 cytoskeleton cellular_component A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. [GOC:mah, PMID:16959967, PMID:27419875]
GO:0018107 peptidyl-threonine phosphorylation biological_process The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. [RESID:AA0038]
GO:0018105 peptidyl-serine phosphorylation biological_process The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. [RESID:AA0037]