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ECM1-202 ,ECM1 ,Q16610
  • Uniprot Accession= Q16610
  • Ensembl Transcript= ENST00000369047.9
  • Uniprot Name= ECM1
  • Name= Extracellular matrix protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 27
GO term GO name GO namespace GO def
GO:0002020 protease binding molecular_function Binding to a protease or a peptidase. [GOC:hjd]
GO:0005134 interleukin-2 receptor binding molecular_function Binding to an interleukin-2 receptor. [GOC:ai]
GO:0005201 extracellular matrix structural constituent molecular_function The action of a molecule that contributes to the structural integrity of the extracellular matrix. [GOC:mah]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0001503 ossification biological_process The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. [GOC:mtg_mpo, PMID:17572649]
GO:0001525 angiogenesis biological_process Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. [ISBN:0878932453]
GO:0001938 positive regulation of endothelial cell proliferation biological_process Any process that activates or increases the rate or extent of endothelial cell proliferation. [GOC:add]
GO:0001960 negative regulation of cytokine-mediated signaling pathway biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway. [GOC:hjd]
GO:0002063 chondrocyte development biological_process The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. [GOC:dph]
GO:0002828 regulation of type 2 immune response biological_process Any process that modulates the frequency, rate, or extent of a type 2 immune response. [GOC:add]
GO:0003416 endochondral bone growth biological_process The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. [GOC:ascb_2009, GOC:dph, GOC:tb]
GO:0006357 regulation of transcription by RNA polymerase II biological_process Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH]
GO:0006954 inflammatory response biological_process The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732]
GO:0007165 signal transduction biological_process The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. [GOC:go_curators, GOC:mtg_signaling_feb11]
GO:0010466 negative regulation of peptidase activity biological_process Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. [GOC:dph, GOC:tb]
GO:0030502 negative regulation of bone mineralization biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. [GOC:go_curators]
GO:0031214 biomineral tissue development biological_process Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation. [PMID:15132736]
GO:0043123 positive regulation of canonical NF-kappaB signal transduction biological_process Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade. [GOC:jl]
GO:0045766 positive regulation of angiogenesis biological_process Any process that activates or increases angiogenesis. [GOC:go_curators]
GO:2000404 regulation of T cell migration biological_process Any process that modulates the frequency, rate or extent of T cell migration. [GOC:mah]
GO:0005576 extracellular region cellular_component The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
GO:0031012 extracellular matrix cellular_component A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324]
GO:0031089 platelet dense granule lumen cellular_component The volume enclosed by the membrane of the platelet dense granule. [GOC:mah]
GO:0062023 collagen-containing extracellular matrix cellular_component An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. [GOC:BHF, GOC:rph, PMID:21123617]
GO:0070062 extracellular exosome cellular_component A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]
GO:0030500 regulation of bone mineralization biological_process Any process that modulates the frequency, rate or extent of bone mineralization. [GOC:go_curators]
GO:0005615 extracellular space cellular_component That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]