GO term | GO name | GO namespace | GO def |
GO:0005102 | signaling receptor binding | molecular_function | Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:bf, GOC:ceb, ISBN:0198506732] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0046875 | ephrin receptor binding | molecular_function | Binding to an ephrin receptor. [GOC:ai] |
GO:0000122 | negative regulation of transcription by RNA polymerase II | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH] |
GO:0001525 | angiogenesis | biological_process | Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. [ISBN:0878932453] |
GO:0001934 | positive regulation of protein phosphorylation | biological_process | Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. [GOC:hjd] |
GO:0003180 | aortic valve morphogenesis | biological_process | The process in which the structure of the aortic valve is generated and organized. [GOC:mtg_heart] |
GO:0003183 | mitral valve morphogenesis | biological_process | The process in which the structure of the mitral valve is generated and organized. [GOC:mtg_heart] |
GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation | biological_process | A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve. [GOC:mtg_heart] |
GO:0007267 | cell-cell signaling | biological_process | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. [GOC:dos, GOC:mah] |
GO:0010719 | negative regulation of epithelial to mesenchymal transition | biological_process | Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:BHF, GOC:dph, GOC:tb] |
GO:0014028 | notochord formation | biological_process | The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. [GOC:dh, GOC:ef] |
GO:0016477 | cell migration | biological_process | The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] |
GO:0033628 | regulation of cell adhesion mediated by integrin | biological_process | Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin. [GOC:add] |
GO:0034446 | substrate adhesion-dependent cell spreading | biological_process | The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate. [GOC:mah, GOC:pf, PMID:17050732] |
GO:0043409 | negative regulation of MAPK cascade | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. [GOC:go_curators] |
GO:0043410 | positive regulation of MAPK cascade | biological_process | Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. [GOC:go_curators] |
GO:0043535 | regulation of blood vessel endothelial cell migration | biological_process | Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels. [GOC:go_curators] |
GO:0045765 | regulation of angiogenesis | biological_process | Any process that modulates the frequency, rate or extent of angiogenesis. [GOC:go_curators] |
GO:0048013 | ephrin receptor signaling pathway | biological_process | The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb] |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | biological_process | Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. [GOC:ai] |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | biological_process | Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. [GOC:ai] |
GO:0050770 | regulation of axonogenesis | biological_process | Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. [GOC:ai] |
GO:0050821 | protein stabilization | biological_process | Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. [GOC:ai] |
GO:0061002 | negative regulation of dendritic spine morphogenesis | biological_process | Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. [GOC:dph] |
GO:0061098 | positive regulation of protein tyrosine kinase activity | biological_process | Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity. [GOC:dph, GOC:tb] |
GO:0070244 | negative regulation of thymocyte apoptotic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] |
GO:1902004 | positive regulation of amyloid-beta formation | biological_process | Any process that activates or increases the frequency, rate or extent of amyloid-beta formation. [GOC:dph, GOC:TermGenie, PMID:17098871] |
GO:1902961 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:24577224] |
GO:1903051 | negative regulation of proteolysis involved in protein catabolic process | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process. [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18307834] |
GO:0005576 | extracellular region | cellular_component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0098552 | side of membrane | cellular_component | A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface. [GOC:dos] |
GO:0007411 | axon guidance | biological_process | The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues. [ISBN:0878932437] |