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EPRS1-201 ,EPRS1 ,P07814
  • Number of GO Term: 23
GO term GO name GO namespace GO def
GO:0004818 glutamate-tRNA ligase activity molecular_function Catalysis of the reaction
GO:0004827 proline-tRNA ligase activity molecular_function Catalysis of the reaction
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0008270 zinc ion binding molecular_function Binding to a zinc ion (Zn). [GOC:ai]
GO:0035613 RNA stem-loop binding molecular_function Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop. [GOC:sart, PMID:16568238, PMID:20455544]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0042803 protein homodimerization activity molecular_function Binding to an identical protein to form a homodimer. [GOC:jl]
GO:0051020 GTPase binding molecular_function Binding to a GTPase, any enzyme that catalyzes the hydrolysis of GTP. [GOC:ai]
GO:0006418 tRNA aminoacylation for protein translation biological_process The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis. [GOC:ma]
GO:0006424 glutamyl-tRNA aminoacylation biological_process The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. [GOC:mcc, ISBN:0716730510]
GO:0006433 prolyl-tRNA aminoacylation biological_process The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA. [GOC:mah, ISBN:0716730510]
GO:0017148 negative regulation of translation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. [GOC:isa_complete]
GO:0032869 cellular response to insulin stimulus biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732]
GO:0071346 cellular response to type II interferon biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far. [GOC:mah]
GO:0140212 regulation of long-chain fatty acid import into cell biological_process Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell. [PMID:28178239]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0017101 aminoacyl-tRNA synthetase multienzyme complex cellular_component A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as
GO:0097452 GAIT complex cellular_component A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP. [GOC:br, PMID:15479637, PMID:23071094]
GO:1990904 ribonucleoprotein complex cellular_component A macromolecular complex that contains both RNA and protein molecules. [GOC:krc, GOC:vesicles]