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EPS8L3-202 ,EPS8L3 ,Q8TE67
  • Uniprot Accession= Q8TE67
  • Ensembl Transcript= ENST00000361965.9
  • Uniprot Name= EPS8L3
  • Name= Epidermal growth factor receptor kinase substrate 8-like protein 3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 11
GO term GO name GO namespace GO def
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. [GOC:kd, GOC:mah, PMID:23303910, PMID:27218782]
GO:0051015 actin filament binding molecular_function Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. [ISBN:0198506732]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0042634 regulation of hair cycle biological_process Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. [GOC:go_curators, PMID:12230507]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:1900029 positive regulation of ruffle assembly biological_process Any process that activates or increases the frequency, rate or extent of ruffle assembly. [GOC:TermGenie, GOC:yaf]
GO:0007266 Rho protein signal transduction biological_process An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal. [GOC:bf]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0032587 ruffle membrane cellular_component The portion of the plasma membrane surrounding a ruffle. [GOC:mah]
GO:0003779 actin binding molecular_function Binding to monomeric or multimeric forms of actin, including actin filaments. [GOC:clt]
GO:0035023 regulation of Rho protein signal transduction biological_process Any process that modulates the frequency, rate or extent of Rho protein signal transduction. [GOC:bf]