GO term | GO name | GO namespace | GO def |
GO:0001618 | virus receptor activity | molecular_function | Combining with a virus component and mediating entry of the virus into the cell. [GOC:bf, GOC:dph, PMID:7621403, UniProtKB-KW:KW-1183] |
GO:0005178 | integrin binding | molecular_function | Binding to an integrin. [GOC:ceb] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0030165 | PDZ domain binding | molecular_function | Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins. [GOC:go_curators, Pfam:PF00595] |
GO:0042803 | protein homodimerization activity | molecular_function | Binding to an identical protein to form a homodimer. [GOC:jl] |
GO:0045296 | cadherin binding | molecular_function | Binding to cadherin, a type I membrane protein involved in cell adhesion. [GOC:bf] |
GO:0001817 | regulation of cytokine production | biological_process | Any process that modulates the frequency, rate, or extent of production of a cytokine. [GOC:add, ISBN:0781735149] |
GO:0006954 | inflammatory response | biological_process | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732] |
GO:0007159 | leukocyte cell-cell adhesion | biological_process | The attachment of a leukocyte to another cell via adhesion molecules. [GOC:go_curators] |
GO:0008360 | regulation of cell shape | biological_process | Any process that modulates the surface configuration of a cell. [GOC:dph, GOC:go_curators, GOC:tb] |
GO:0031032 | actomyosin structure organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. [GOC:dph, GOC:jl, GOC:mah] |
GO:0032956 | regulation of actin cytoskeleton organization | biological_process | Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. [GOC:mah] |
GO:0035025 | positive regulation of Rho protein signal transduction | biological_process | Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction. [GOC:bf] |
GO:0035633 | maintenance of blood-brain barrier | biological_process | Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation. [GOC:aruk, GOC:bc, GOC:bf, GOC:sl, PMID:20080302, PMID:30280653] |
GO:0035683 | memory T cell extravasation | biological_process | The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive. [CL:0000813, GOC:BHF] |
GO:0046718 | symbiont entry into host cell | biological_process | The process by which a symbiont breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the symbiont or its genome is released into the host cell. [GOC:jl] |
GO:0050892 | intestinal absorption | biological_process | Any process in which nutrients are taken up from the contents of the intestine. [GOC:ai, GOC:dph] |
GO:0051493 | regulation of cytoskeleton organization | biological_process | Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. [GOC:ai] |
GO:0051497 | negative regulation of stress fiber assembly | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. [GOC:ai] |
GO:0071260 | cellular response to mechanical stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. [GOC:mah] |
GO:0072659 | protein localization to plasma membrane | biological_process | A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. [GOC:mah] |
GO:0090557 | establishment of endothelial intestinal barrier | biological_process | The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition. [GOC:krc, PMID:22155109] |
GO:0090559 | regulation of membrane permeability | biological_process | Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane. [GOC:kmv, PMID:22677064] |
GO:0098609 | cell-cell adhesion | biological_process | The attachment of one cell to another cell via adhesion molecules. [GOC:dos] |
GO:1901731 | positive regulation of platelet aggregation | biological_process | Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. [GOC:fj, GOC:TermGenie] |
GO:1902396 | protein localization to bicellular tight junction | biological_process | A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction. [GOC:TermGenie, PMID:18332111] |
GO:1903142 | positive regulation of establishment of endothelial barrier | biological_process | Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier. [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24851274] |
GO:2000810 | regulation of bicellular tight junction assembly | biological_process | Any process that modulates the frequency, rate or extent of tight junction assembly. [GOC:BHF] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0005911 | cell-cell junction | cellular_component | A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. [GOC:aruk, GOC:bc, GOC:dgh, GOC:hb, GOC:mah, PMID:21422226, PMID:28096264] |
GO:0005923 | bicellular tight junction | cellular_component | An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. [GOC:mah, ISBN:0815332181] |
GO:0030054 | cell junction | cellular_component | A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. [GOC:aruk, GOC:bc, GOC:mah, http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html, ISBN:0198506732, PMID:26820516, PMID:28096264] |
GO:0070062 | extracellular exosome | cellular_component | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] |
GO:0070160 | tight junction | cellular_component | A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. [ISBN:0815332181] |
GO:0032991 | protein-containing complex | cellular_component | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah] |