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F3-201 ,F3 ,P13726
  • Uniprot Accession= P13726
  • Ensembl Transcript= ENST00000334047.12
  • Uniprot Name= F3
  • Name= Tissue factor
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 26
GO term GO name GO namespace GO def
GO:0010628 positive regulation of gene expression biological_process Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018]
GO:0032757 positive regulation of interleukin-8 production biological_process Any process that activates or increases the frequency, rate, or extent of interleukin-8 production. [GOC:mah]
GO:0004252 serine-type endopeptidase activity molecular_function Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]
GO:0002020 protease binding molecular_function Binding to a protease or a peptidase. [GOC:hjd]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005543 phospholipid binding molecular_function Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. [ISBN:0198506732]
GO:0001938 positive regulation of endothelial cell proliferation biological_process Any process that activates or increases the rate or extent of endothelial cell proliferation. [GOC:add]
GO:0002541 activation of plasma proteins involved in acute inflammatory response biological_process Any process activating plasma proteins by proteolysis as part of an acute inflammatory response. [GOC:jal, ISBN:0781735149]
GO:0002543 activation of blood coagulation via clotting cascade biological_process Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot. [GOC:jal, ISBN:0781735149]
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process biological_process Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. [GOC:al, GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, PMID:18328827, Wikipedia:Caspase]
GO:0007596 blood coagulation biological_process The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway biological_process Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. [GOC:dph, GOC:hjd, GOC:tb]
GO:0016485 protein processing biological_process Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. [GOC:curators, GOC:jl, GOC:jsg]
GO:0030335 positive regulation of cell migration biological_process Any process that activates or increases the frequency, rate or extent of cell migration. [GOC:go_curators]
GO:0032008 positive regulation of TOR signaling biological_process Any process that activates or increases the frequency, rate or extent of TOR signaling. [GOC:mah]
GO:0045766 positive regulation of angiogenesis biological_process Any process that activates or increases angiogenesis. [GOC:go_curators]
GO:0050927 positive regulation of positive chemotaxis biological_process Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. [GOC:ai]
GO:0005615 extracellular space cellular_component That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0009897 external side of plasma membrane cellular_component The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. [GOC:dos, GOC:tb]
GO:0009986 cell surface cellular_component The external part of the cell wall and/or plasma membrane. [GOC:jl, GOC:mtg_sensu, GOC:sm]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0062023 collagen-containing extracellular matrix cellular_component An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. [GOC:BHF, GOC:rph, PMID:21123617]
GO:1905286 serine-type peptidase complex cellular_component A protein complex which is capable of serine-type peptidase activity. [GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:18640965]
GO:0019221 cytokine-mediated signaling pathway biological_process The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling, PMID:19295629]
GO:0004896 cytokine receptor activity molecular_function Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:add, GOC:mah]