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FBXO42-201 ,FBXO42 ,Q6P3S6
  • Uniprot Accession= Q6P3S6
  • Ensembl Transcript= ENST00000375592.8
  • Uniprot Name= FBXO42
  • Name= F-box only protein 42
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 3
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0019005 SCF ubiquitin ligase complex cellular_component A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). [PMID:15571813, PMID:15688063]
GO:1990756 ubiquitin ligase-substrate adaptor activity molecular_function The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins. [PMID:24658274]