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FCMR-201 ,FCMR ,O60667
  • Number of GO Term: 17
GO term GO name GO namespace GO def
GO:0001790 polymeric immunoglobulin binding molecular_function Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes. [GOC:add, ISBN:0781735149]
GO:0001791 IgM binding molecular_function Binding to an immunoglobulin of the IgM isotype. [GOC:add, ISBN:0781735149]
GO:0002172 high-affinity IgM receptor activity molecular_function Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:hjd, GOC:signaling]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0002414 immunoglobulin transcytosis in epithelial cells biological_process The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other. [GOC:add, ISBN:0781735149, ISBN:081533642X, PMID:16048543]
GO:0002455 humoral immune response mediated by circulating immunoglobulin biological_process An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus. [GO_REF:0000022, GOC:add, ISBN:0781735149]
GO:0006968 cellular defense response biological_process A defense response that is mediated by cells. [GOC:ebc]
GO:0038093 Fc receptor signaling pathway biological_process The series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. [GOC:phg, Wikipedia:Fc_receptor]
GO:0043066 negative regulation of apoptotic process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
GO:0050855 regulation of B cell receptor signaling pathway biological_process Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. [GOC:ai]
GO:0160006 Fc receptor-mediated immune complex endocytosis biological_process An endocytosis process mediated by the Fc receptor for the purpose of delivery of antigen-bound immunoglobulin to an intracellular compartment where the antigen can be processed and loaded onto MHC molecules. This process selectively targets antigens for presentation by MHC class II or cross-presentation by MHC class I. [PMID:28389502, PMID:9143687, PMID:9463401]
GO:0005576 extracellular region cellular_component The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
GO:0005765 lysosomal membrane cellular_component The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0031901 early endosome membrane cellular_component The lipid bilayer surrounding an early endosome. [GOC:pz]
GO:0032588 trans-Golgi network membrane cellular_component The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network. [GOC:mah]
GO:0004888 transmembrane signaling receptor activity molecular_function Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. [GOC:go_curators, Wikipedia:Transmembrane_receptor]