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FOXD3-201 ,FOXD3 ,Q9UJU5
  • Uniprot Accession= Q9UJU5
  • Ensembl Transcript= ENST00000371116.4
  • Uniprot Name= FOXD3
  • Name= Forkhead box protein D3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 15
GO term GO name GO namespace GO def
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding molecular_function Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. [GOC:txnOH]
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. [GOC:txnOH-2018]
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific molecular_function A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II. [GOC:txnOH-2018]
GO:0003700 DNA-binding transcription factor activity molecular_function A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. [GOC:txnOH-2018]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:1990837 sequence-specific double-stranded DNA binding molecular_function Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. [GOC:dos, GOC:sl]
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH]
GO:0001701 in utero embryonic development biological_process The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. [GOC:go_curators, GOC:mtg_sensu]
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. [GOC:go_curators, GOC:txnOH]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0000785 chromatin cellular_component The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. [GOC:elh, PMID:20404130]
GO:0006357 regulation of transcription by RNA polymerase II biological_process Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH]
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. [GOC:txnOH-2018]
GO:0009653 anatomical structure morphogenesis biological_process The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. [GOC:go_curators, ISBN:0521436125]
GO:0030154 cell differentiation biological_process The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [ISBN:0198506732]