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FYB2-201 ,FYB2 ,Q5VWT5
  • Uniprot Accession= Q5VWT5
  • Ensembl Transcript= ENST00000343433.7
  • Uniprot Name= FYB2
  • Name= FYN-binding protein 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 8
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0033627 cell adhesion mediated by integrin biological_process The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. [GOC:add, PMID:12213832, PMID:14754902]
GO:0050852 T cell receptor signaling pathway biological_process The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. [GOC:add]
GO:0001772 immunological synapse cellular_component An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. [GOC:mgi_curators, PMID:11244041, PMID:11376300]
GO:0045121 membrane raft cellular_component Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. [PMID:16645198, PMID:20044567]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0007229 integrin-mediated signaling pathway biological_process The series of molecular signals initiated by an extracellular ligand binding to an integrin on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]
GO:0072659 protein localization to plasma membrane biological_process A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. [GOC:mah]