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GBP5-201 ,GBP5 ,Q96PP8
  • Uniprot Accession= Q96PP8
  • Ensembl Transcript= ENST00000370459.8
  • Uniprot Name= GBP5
  • Name= Guanylate-binding protein 5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 33
GO term
GO name
GO namespace
GO def
GO:0003924 GTPase activity molecular_function Catalysis of the reaction
GO:0004866 endopeptidase inhibitor activity molecular_function Binds to and stops, prevents or reduces the activity of an endopeptidase. [GOC:jl]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0042803 protein homodimerization activity molecular_function Binding to an identical protein to form a homodimer. [GOC:jl]
GO:0140678 molecular function inhibitor activity molecular_function A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target. [GOC:curators]
GO:0002218 activation of innate immune response biological_process Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species. [GO_REF:0000022, GOC:add, GOC:mtg_sensu, ISBN:0781735149, PMID:15199967, PMID:16177805]
GO:0006605 protein targeting biological_process The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. [GOC:ma]
GO:0006954 inflammatory response biological_process The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732]
GO:0032731 positive regulation of interleukin-1 beta production biological_process Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production. [GOC:mah]
GO:0032741 positive regulation of interleukin-18 production biological_process Any process that activates or increases the frequency, rate, or extent of interleukin-18 production. [GOC:mah]
GO:0034067 protein localization to Golgi apparatus biological_process A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. [GOC:mah]
GO:0042742 defense response to bacterium biological_process Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. [GOC:jl]
GO:0045089 positive regulation of innate immune response biological_process Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. [GOC:ebc]
GO:0051289 protein homotetramerization biological_process The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits. [GOC:go_curators]
GO:0051607 defense response to virus biological_process Reactions triggered in response to the presence of a virus that act to protect the cell or organism. [GOC:ai]
GO:0051715 cytolysis in another organism biological_process The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm. [GOC:ai, PMID:22484288]
GO:0071222 cellular response to lipopolysaccharide biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. [GOC:mah]
GO:0071346 cellular response to type II interferon biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far. [GOC:mah]
GO:0140639 positive regulation of pyroptosis biological_process Any process that increases the frequency, rate or extent of pyroptosis. [PMID:24626226]
GO:0140973 positive regulation of AIM2 inflammasome complex assembly biological_process Any process that activates or increases the frequency, rate or extent of AIM2 inflammasome complex assembly. [PMID:33467177]
GO:1900017 positive regulation of cytokine production involved in inflammatory response biological_process Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response. [GOC:TermGenie]
GO:1900227 positive regulation of NLRP3 inflammasome complex assembly biological_process Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly. [GOC:TermGenie]
GO:0000139 Golgi membrane cellular_component The lipid bilayer surrounding any of the compartments of the Golgi apparatus. [GOC:mah]
GO:0005794 Golgi apparatus cellular_component A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. [ISBN:0198506732]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0030659 cytoplasmic vesicle membrane cellular_component The lipid bilayer surrounding a cytoplasmic vesicle. [GOC:mah]
GO:0048471 perinuclear region of cytoplasm cellular_component Cytoplasm situated near, or occurring around, the nucleus. [GOC:jid]
GO:0098552 side of membrane cellular_component A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface. [GOC:dos]
GO:0106139 symbiont cell surface cellular_component The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. [GOC:rjd, PMID:30049880]
GO:0005525 GTP binding molecular_function Binding to GTP, guanosine triphosphate. [GOC:ai]
GO:0031410 cytoplasmic vesicle cellular_component A vesicle found in the cytoplasm of a cell. [GOC:ai, GOC:mah, GOC:vesicles]