GO term | GO name | GO namespace | GO def |
GO:0007166 | cell surface receptor signaling pathway | biological_process | The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:mah, GOC:pr, GOC:signaling] |
GO:0008285 | negative regulation of cell population proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of cell proliferation. [GOC:go_curators] |
GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | biological_process | Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. [GOC:mah] |
GO:0032743 | positive regulation of interleukin-2 production | biological_process | Any process that activates or increases the frequency, rate, or extent of interleukin-2 production. [GOC:mah] |
GO:0005102 | signaling receptor binding | molecular_function | Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:bf, GOC:ceb, ISBN:0198506732] |
GO:0005171 | hepatocyte growth factor receptor binding | molecular_function | Binding to an hepatocyte growth factor receptor. [GOC:ai] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0031625 | ubiquitin protein ligase binding | molecular_function | Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp] |
GO:0055105 | ubiquitin-protein transferase inhibitor activity | molecular_function | Binds to and stops, prevents or reduces the activity of a ubiquitin-protein transferase. [GOC:BHF, GOC:rl] |
GO:0001570 | vasculogenesis | biological_process | The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. [PMID:8999798] |
GO:0001819 | positive regulation of cytokine production | biological_process | Any process that activates or increases the frequency, rate or extent of production of a cytokine. [GOC:add, ISBN:0781735149] |
GO:0001843 | neural tube closure | biological_process | The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. [GOC:dph, ISBN:0878932437] |
GO:0040029 | epigenetic regulation of gene expression | biological_process | A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal. [PMID:10521337, PMID:11498582, PMID:22243696, PMID:34414474] |
GO:0042130 | negative regulation of T cell proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of T cell proliferation. [GOC:jl] |
GO:0042327 | positive regulation of phosphorylation | biological_process | Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. [GOC:jl] |
GO:0042692 | muscle cell differentiation | biological_process | The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. [CL:0000187, GOC:go_curators] |
GO:0031461 | cullin-RING ubiquitin ligase complex | cellular_component | Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity. [PMID:15571813, PMID:15688063] |
GO:0031462 | Cul2-RING ubiquitin ligase complex | cellular_component | A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. [PMID:15571813, PMID:15688063] |
GO:0031463 | Cul3-RING ubiquitin ligase complex | cellular_component | A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein. [PMID:15571813, PMID:15688063] |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | cellular_component | A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein. [PMID:15571813, PMID:15688063] |
GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |