Total number of protein in "GO:0000077" GO term: 38
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0000077 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| ATR-201 | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:0000077 | Census, Compendium | Yes | 261 | 0.098714069591528 | 107 | 11 | 0.0041603630862329 | 1 |
| ATRIP-201 | ATRIP | Q8WXE1 | ATR-interacting protein | chr3 | GO:0000077 | Not Cancer Driver | No | 50 | 0.0632111251580278 | 388 | 22 | 0.0278128950695322 | 0 |
| BRIP1-201 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | GO:0000077 | Census | Yes | 118 | 0.0944755804643715 | 399 | 41 | 0.032826261008807 | 6 |
| CDC5L-201 | CDC5L | Q99459 | Cell division cycle 5-like protein | chr6 | GO:0000077 | Not Cancer Driver | No | 60 | 0.0748129675810473 | 621 | 46 | 0.0573566084788029 | 0 |
| CEP63-216 | CEP63 | Q96MT8 | Centrosomal protein of 63 kDa | chr3 | GO:0000077 | Not Cancer Driver | No | 77 | 0.1095305832147937 | 508 | 50 | 0.0711237553342816 | 0 |
| CHEK1-204 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0000077 | Not Cancer Driver | No | 42 | 0.088235294117647 | 86 | 13 | 0.0273109243697479 | 0 |
| CHEK2-206 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:0000077 | Census, Compendium | Yes | 72 | 0.1325966850828729 | 157 | 19 | 0.0349907918968692 | 11 |
| CLOCK-211 | CLOCK | O15516 | Circadian locomoter output cycles protein kaput | chr4 | GO:0000077 | Not Cancer Driver | No | 56 | 0.0661938534278959 | 459 | 25 | 0.0295508274231678 | 0 |
| CLSPN-202 | CLSPN | Q9HAW4 | Claspin | chr1 | GO:0000077 | Not Cancer Driver | No | 92 | 0.0687079910380881 | 1287 | 89 | 0.0664675130694548 | 0 |
| DONSON-201 | DONSON | Q9NYP3 | Protein downstream neighbor of Son | chr21 | GO:0000077 | Not Cancer Driver | No | 30 | 0.0530035335689045 | 218 | 9 | 0.0159010600706713 | 6 |
| DOT1L-201 | DOT1L | Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | chr19 | GO:0000077 | Compendium | Yes | 135 | 0.0878334417696811 | 990 | 81 | 0.0527000650618087 | 0 |
| DTX3L-201 | DTX3L | Q8TDB6 | E3 ubiquitin-protein ligase DTX3L | chr3 | GO:0000077 | Not Cancer Driver | No | 60 | 0.081081081081081 | 260 | 19 | 0.0256756756756756 | 0 |
| E2F1-201 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:0000077 | Not Cancer Driver | No | 39 | 0.0892448512585812 | 273 | 17 | 0.0389016018306636 | 0 |
| EIF2AK4-201 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | GO:0000077 | Not Cancer Driver | No | 113 | 0.0685263796240145 | 496 | 34 | 0.0206185567010309 | 2 |
| ERCC6-201 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0000077 | Not Cancer Driver | No | 142 | 0.0951105157401205 | 837 | 82 | 0.0549229738780977 | 9 |
| FBXO6-201 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | GO:0000077 | Not Cancer Driver | No | 25 | 0.0853242320819112 | 27 | 3 | 0.0102389078498293 | 0 |
| GNB1L-201 | GNB1L | Q9BYB4 | Guanine nucleotide-binding protein subunit beta-like protein 1 | chr22 | GO:0000077 | Not Cancer Driver | No | 51 | 0.1559633027522936 | 18 | 0 | 0.0 | 0 |
| H2AX-202 | H2AX | P16104 | Histone H2AX | chr11 | GO:0000077 | Not Cancer Driver | No | 19 | 0.1328671328671328 | 68 | 8 | 0.0559440559440559 | 0 |
| HINFP-201 | HINFP | Q9BQA5 | Histone H4 transcription factor | chr11 | GO:0000077 | Not Cancer Driver | No | 49 | 0.0947775628626692 | 156 | 20 | 0.0386847195357833 | 0 |
| HUS1-201 | HUS1 | O60921 | Checkpoint protein HUS1 | chr7 | GO:0000077 | Not Cancer Driver | No | 19 | 0.0678571428571428 | 17 | 1 | 0.0035714285714285 | 0 |
| INTS7-203 | INTS7 | Q9NVH2 | Integrator complex subunit 7 | chr1 | GO:0000077 | Not Cancer Driver | No | 74 | 0.0769230769230769 | 89 | 9 | 0.0093555093555093 | 0 |
| MAP3K20-202 | MAP3K20 | Q9NYL2 | Mitogen-activated protein kinase kinase kinase 20 | chr2 | GO:0000077 | Not Cancer Driver | No | 71 | 0.08875 | 296 | 35 | 0.04375 | 2 |
| MAPK14-201 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0000077 | Not Cancer Driver | No | 22 | 0.0611111111111111 | 25 | 0 | 0.0 | 0 |
| NBN-201 | NBN | O60934 | Nibrin | chr8 | GO:0000077 | Census | Yes | 63 | 0.0835543766578249 | 420 | 45 | 0.059681697612732 | 1 |
| PARP9-201 | PARP9 | Q8IXQ6 | Protein mono-ADP-ribosyltransferase PARP9 | chr3 | GO:0000077 | Not Cancer Driver | No | 85 | 0.0995316159250585 | 45 | 3 | 0.0035128805620608 | 0 |
| PRPF19-201 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | GO:0000077 | Not Cancer Driver | No | 43 | 0.0853174603174603 | 110 | 12 | 0.0238095238095238 | 0 |
| PTPN11-201 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0000077 | Census, Compendium | Yes | 92 | 0.1551433389544688 | 260 | 27 | 0.0455311973018549 | 44 |
| RAD1-203 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0000077 | Not Cancer Driver | No | 19 | 0.0673758865248227 | 4 | 0 | 0.0 | 0 |
| RAD17-208 | RAD17 | O75943 | Cell cycle checkpoint protein RAD17 | chr5 | GO:0000077 | Census | Yes | 53 | 0.0778267254038179 | 207 | 12 | 0.0176211453744493 | 0 |
| RAD9A-201 | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:0000077 | Not Cancer Driver | No | 32 | 0.0818414322250639 | 136 | 7 | 0.0179028132992327 | 0 |
| RHNO1-204 | RHNO1 | Q9BSD3 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 | chr12 | GO:0000077 | Not Cancer Driver | No | 22 | 0.0924369747899159 | 193 | 18 | 0.0756302521008403 | 0 |
| RPA4-201 | RPA4 | Q13156 | Replication protein A 30 kDa subunit | chrX | GO:0000077 | Not Cancer Driver | No | 56 | 0.21455938697318 | 59 | 10 | 0.0383141762452107 | 0 |
| TIPRL-202 | TIPRL | O75663 | TIP41-like protein | chr1 | GO:0000077 | Not Cancer Driver | No | 20 | 0.0735294117647058 | 25 | 1 | 0.0036764705882352 | 0 |
| TOPBP1-201 | TOPBP1 | Q92547 | DNA topoisomerase 2-binding protein 1 | chr3 | GO:0000077 | Not Cancer Driver | No | 121 | 0.0795006570302234 | 579 | 43 | 0.0282522996057818 | 0 |
| TP53BP1-201 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | GO:0000077 | Not Cancer Driver | No | 159 | 0.0806288032454361 | 1638 | 131 | 0.0664300202839756 | 0 |
| UFL1-201 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0000077 | Not Cancer Driver | No | 77 | 0.096977329974811 | 141 | 19 | 0.0239294710327455 | 0 |
| USP28-201 | USP28 | Q96RU2 | Ubiquitin carboxyl-terminal hydrolase 28 | chr11 | GO:0000077 | Not Cancer Driver | No | 106 | 0.0984215413184772 | 311 | 18 | 0.0167130919220055 | 0 |