Total number of protein in "GO:0000082" GO term: 66
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACVR1B-201 | ACVR1B | P36896 | Activin receptor type-1B | chr12 | GO:0000082 | Census | Yes | 95 | 0.1881188118811881 | 0 | 0 | 0.0 | 0 |
BCAT1-201 | BCAT1 | P54687 | Branched-chain-amino-acid aminotransferase, cytosolic | chr12 | GO:0000082 | Not Cancer Driver | No | 53 | 0.1373056994818652 | 8 | 2 | 0.005181347150259 | 0 |
BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0000082 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
BTN2A2-202 | BTN2A2 | Q8WVV5 | Butyrophilin subfamily 2 member A2 | chr6 | GO:0000082 | Not Cancer Driver | No | 58 | 0.1108986615678776 | 24 | 2 | 0.0038240917782026 | 0 |
CACUL1-201 | CACUL1 | Q86Y37 | CDK2-associated and cullin domain-containing protein 1 | chr10 | GO:0000082 | Not Cancer Driver | No | 22 | 0.059620596205962 | 128 | 3 | 0.008130081300813 | 0 |
CAMK2A-201 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | GO:0000082 | Not Cancer Driver | No | 62 | 0.1297071129707113 | 62 | 10 | 0.0209205020920502 | 7 |
CCNA2-201 | CCNA2 | P20248 | Cyclin-A2 | chr4 | GO:0000082 | Not Cancer Driver | No | 34 | 0.0787037037037037 | 187 | 14 | 0.0324074074074074 | 0 |
CCND1-201 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0000082 | Census, Compendium | Yes | 47 | 0.159322033898305 | 32 | 25 | 0.0847457627118644 | 0 |
CCND2-201 | CCND2 | P30279 | G1/S-specific cyclin-D2 | chr12 | GO:0000082 | Census, Compendium | Yes | 29 | 0.1003460207612456 | 30 | 5 | 0.0173010380622837 | 3 |
CCND3-203 | CCND3 | P30281 | G1/S-specific cyclin-D3 | chr6 | GO:0000082 | Census, Compendium | Yes | 24 | 0.0821917808219178 | 46 | 7 | 0.023972602739726 | 0 |
CCNE1-201 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:0000082 | Census | Yes | 44 | 0.1073170731707317 | 142 | 15 | 0.0365853658536585 | 0 |
CCNE2-201 | CCNE2 | O96020 | G1/S-specific cyclin-E2 | chr8 | GO:0000082 | Not Cancer Driver | No | 35 | 0.0866336633663366 | 69 | 9 | 0.0222772277227722 | 0 |
CDC25A-201 | CDC25A | P30304 | M-phase inducer phosphatase 1 | chr3 | GO:0000082 | Not Cancer Driver | No | 45 | 0.0858778625954198 | 314 | 27 | 0.0515267175572519 | 0 |
CDC34-201 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | GO:0000082 | Not Cancer Driver | No | 19 | 0.0805084745762711 | 96 | 7 | 0.0296610169491525 | 0 |
CDC7-201 | CDC7 | O00311 | Cell division cycle 7-related protein kinase | chr1 | GO:0000082 | Not Cancer Driver | No | 49 | 0.0853658536585365 | 187 | 17 | 0.0296167247386759 | 0 |
CDK1-203 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0000082 | Not Cancer Driver | No | 26 | 0.0875420875420875 | 1 | 0 | 0.0 | 0 |
CDK2-201 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0000082 | Not Cancer Driver | No | 17 | 0.0570469798657718 | 0 | 0 | 0.0 | 0 |
CDK3-202 | CDK3 | Q00526 | Cyclin-dependent kinase 3 | chr17 | GO:0000082 | Not Cancer Driver | No | 29 | 0.0950819672131147 | 17 | 1 | 0.0032786885245901 | 0 |
CDK4-201 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | GO:0000082 | Census, Compendium | Yes | 38 | 0.1254125412541254 | 52 | 3 | 0.0099009900990099 | 2 |
CDK6-202 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | GO:0000082 | Census | Yes | 25 | 0.0766871165644171 | 24 | 3 | 0.00920245398773 | 1 |
CDKN1A-201 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0000082 | Census, Compendium | Yes | 38 | 0.2317073170731707 | 121 | 25 | 0.1524390243902439 | 0 |
CDKN1B-201 | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0000082 | Census, Compendium | Yes | 14 | 0.0707070707070707 | 199 | 14 | 0.0707070707070707 | 0 |
CDKN3-202 | CDKN3 | Q16667 | Cyclin-dependent kinase inhibitor 3 | chr14 | GO:0000082 | Not Cancer Driver | No | 12 | 0.0566037735849056 | 33 | 1 | 0.0047169811320754 | 9 |
CUL1-201 | CUL1 | Q13616 | Cullin-1 | chr7 | GO:0000082 | Not Cancer Driver | No | 127 | 0.163659793814433 | 65 | 9 | 0.0115979381443298 | 0 |
CUL2-203 | CUL2 | Q13617 | Cullin-2 | chr10 | GO:0000082 | Not Cancer Driver | No | 64 | 0.0859060402684563 | 66 | 2 | 0.0026845637583892 | 0 |
CUL3-201 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0000082 | Census, Compendium | Yes | 98 | 0.1276041666666666 | 168 | 18 | 0.0234375 | 3 |
CUL4A-202 | CUL4A | Q13619 | Cullin-4A | chr13 | GO:0000082 | Not Cancer Driver | No | 54 | 0.0711462450592885 | 102 | 2 | 0.0026350461133069 | 0 |
CUL4B-231 | CUL4B | Q13620 | Cullin-4B | chrX | GO:0000082 | Not Cancer Driver | No | 83 | 0.0909090909090909 | 207 | 23 | 0.0251916757940854 | 2 |
CUL5-201 | CUL5 | Q93034 | Cullin-5 | chr11 | GO:0000082 | Not Cancer Driver | No | 69 | 0.0884615384615384 | 5 | 1 | 0.0012820512820512 | 0 |
DBF4-201 | DBF4 | Q9UBU7 | Protein DBF4 homolog A | chr7 | GO:0000082 | Not Cancer Driver | No | 48 | 0.0712166172106825 | 334 | 18 | 0.0267062314540059 | 0 |
E2F3-201 | E2F3 | O00716 | Transcription factor E2F3 | chr6 | GO:0000082 | Not Cancer Driver | No | 27 | 0.0580645161290322 | 253 | 11 | 0.0236559139784946 | 0 |
EIF4E-203 | EIF4E | P06730 | Eukaryotic translation initiation factor 4E | chr4 | GO:0000082 | Not Cancer Driver | No | 18 | 0.0829493087557603 | 54 | 4 | 0.0184331797235023 | 0 |
EIF4EBP1-201 | EIF4EBP1 | Q13541 | Eukaryotic translation initiation factor 4E-binding protein 1 | chr8 | GO:0000082 | Not Cancer Driver | No | 8 | 0.0677966101694915 | 118 | 8 | 0.0677966101694915 | 0 |
EZH2-203 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0000082 | Census, Compendium | Yes | 74 | 0.099195710455764 | 284 | 32 | 0.0428954423592493 | 11 |
GPR132-201 | GPR132 | Q9UNW8 | Probable G-protein coupled receptor 132 | chr14 | GO:0000082 | Not Cancer Driver | No | 49 | 0.1289473684210526 | 20 | 2 | 0.0052631578947368 | 0 |
GSPT1-201 | GSPT1 | P15170 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A | chr16 | GO:0000082 | Not Cancer Driver | No | 34 | 0.0681362725450901 | 149 | 10 | 0.0200400801603206 | 0 |
HINFP-201 | HINFP | Q9BQA5 | Histone H4 transcription factor | chr11 | GO:0000082 | Not Cancer Driver | No | 49 | 0.0947775628626692 | 156 | 20 | 0.0386847195357833 | 0 |
ID4-201 | ID4 | P47928 | DNA-binding protein inhibitor ID-4 | chr6 | GO:0000082 | Not Cancer Driver | No | 5 | 0.031055900621118 | 72 | 1 | 0.0062111801242236 | 0 |
IQGAP3-201 | IQGAP3 | Q86VI3 | Ras GTPase-activating-like protein IQGAP3 | chr1 | GO:0000082 | Not Cancer Driver | No | 169 | 0.1036174126302881 | 259 | 26 | 0.0159411404046597 | 0 |
ITGB1-201 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0000082 | Not Cancer Driver | No | 73 | 0.0914786967418546 | 84 | 8 | 0.0100250626566416 | 0 |
KHDRBS1-202 | KHDRBS1 | Q07666 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | chr1 | GO:0000082 | Not Cancer Driver | No | 42 | 0.0948081264108352 | 362 | 37 | 0.0835214446952596 | 0 |
LATS1-207 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | GO:0000082 | Census, Compendium | Yes | 122 | 0.1079646017699115 | 790 | 74 | 0.0654867256637168 | 0 |
LATS2-201 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | GO:0000082 | Census, Compendium | Yes | 101 | 0.0928308823529411 | 690 | 57 | 0.0523897058823529 | 0 |
MNAT1-201 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:0000082 | Not Cancer Driver | No | 20 | 0.0647249190938511 | 64 | 2 | 0.0064724919093851 | 0 |
MYC-206 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0000082 | Census, Compendium | Yes | 72 | 0.158590308370044 | 325 | 41 | 0.0903083700440528 | 0 |
PHF8-204 | PHF8 | Q9UPP1 | Histone lysine demethylase PHF8 | chrX | GO:0000082 | Not Cancer Driver | No | 104 | 0.0981132075471698 | 603 | 58 | 0.0547169811320754 | 1 |
PIAS1-201 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | GO:0000082 | Not Cancer Driver | No | 48 | 0.0737327188940092 | 241 | 25 | 0.0384024577572964 | 0 |
PIM2-201 | PIM2 | Q9P1W9 | Serine/threonine-protein kinase pim-2 | chrX | GO:0000082 | Not Cancer Driver | No | 37 | 0.1189710610932476 | 47 | 7 | 0.022508038585209 | 0 |
PLK2-201 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0000082 | Not Cancer Driver | No | 55 | 0.0802919708029197 | 180 | 18 | 0.0262773722627737 | 0 |
PLK3-201 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0000082 | Not Cancer Driver | No | 55 | 0.0851393188854489 | 203 | 11 | 0.0170278637770897 | 0 |
POLE-201 | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | GO:0000082 | Census, Compendium | Yes | 234 | 0.1023622047244094 | 240 | 31 | 0.0135608048993875 | 3 |
PPP3CA-203 | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0000082 | Compendium | Yes | 63 | 0.1209213051823416 | 140 | 24 | 0.0460652591170825 | 7 |
PPP6C-201 | PPP6C | O00743 | Serine/threonine-protein phosphatase 6 catalytic subunit | chr9 | GO:0000082 | Census, Compendium | Yes | 51 | 0.1672131147540983 | 0 | 0 | 0.0 | 0 |
RB1-201 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0000082 | Census, Compendium | Yes | 89 | 0.0959051724137931 | 282 | 26 | 0.0280172413793103 | 21 |
RBBP8-201 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:0000082 | Not Cancer Driver | No | 72 | 0.0802675585284281 | 751 | 54 | 0.060200668896321 | 1 |
RCC1-214 | RCC1 | P18754 | Regulator of chromosome condensation | chr1 | GO:0000082 | Not Cancer Driver | No | 44 | 0.1045130641330166 | 146 | 16 | 0.0380047505938242 | 0 |
RHOU-201 | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | GO:0000082 | Not Cancer Driver | No | 28 | 0.1085271317829457 | 63 | 6 | 0.0232558139534883 | 0 |
RPS6KB1-201 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0000082 | Not Cancer Driver | No | 36 | 0.0685714285714285 | 226 | 22 | 0.0419047619047619 | 0 |
SKP2-202 | SKP2 | Q13309 | S-phase kinase-associated protein 2 | chr5 | GO:0000082 | Not Cancer Driver | No | 37 | 0.0872641509433962 | 52 | 5 | 0.0117924528301886 | 0 |
SPDYA-201 | SPDYA | Q5MJ70 | Speedy protein A | chr2 | GO:0000082 | Not Cancer Driver | No | 25 | 0.0798722044728434 | 119 | 11 | 0.0351437699680511 | 0 |
TAF10-201 | TAF10 | Q12962 | Transcription initiation factor TFIID subunit 10 | chr11 | GO:0000082 | Not Cancer Driver | No | 10 | 0.0458715596330275 | 131 | 2 | 0.0091743119266055 | 0 |
TRIM71-201 | TRIM71 | Q2Q1W2 | E3 ubiquitin-protein ligase TRIM71 | chr3 | GO:0000082 | Not Cancer Driver | No | 86 | 0.0990783410138248 | 163 | 13 | 0.0149769585253456 | 2 |
USP26-203 | USP26 | Q9BXU7 | Ubiquitin carboxyl-terminal hydrolase 26 | chrX | GO:0000082 | Not Cancer Driver | No | 151 | 0.1653888280394304 | 325 | 49 | 0.0536692223439211 | 0 |
USP29-201 | USP29 | Q9HBJ7 | Ubiquitin carboxyl-terminal hydrolase 29 | chr19 | GO:0000082 | Not Cancer Driver | No | 236 | 0.2559652928416486 | 433 | 114 | 0.123644251626898 | 0 |
USP37-201 | USP37 | Q86T82 | Ubiquitin carboxyl-terminal hydrolase 37 | chr2 | GO:0000082 | Not Cancer Driver | No | 78 | 0.0796731358529111 | 531 | 43 | 0.0439223697650663 | 0 |
ZNF324-201 | ZNF324 | O75467 | Zinc finger protein 324A | chr19 | GO:0000082 | Not Cancer Driver | No | 56 | 0.1012658227848101 | 283 | 26 | 0.0470162748643761 | 0 |