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Total number of protein in "GO:0000086" GO term:  48

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCB1-211 ABCB1 P08183 ATP-dependent translocase ABCB1 chr7 GO:0000086 Compendium Yes 275 0.21484375 103 15 0.01171875 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 GO:0000086 Not Cancer Driver No 94 0.122077922077922 419 52 0.0675324675324675 12
ARPP19-201 ARPP19 P56211 cAMP-regulated phosphoprotein 19 chr15 GO:0000086 Not Cancer Driver No 10 0.0892857142857142 112 10 0.0892857142857142 0
AURKA-208 AURKA O14965 Aurora kinase A chr20 GO:0000086 Not Cancer Driver No 25 0.0620347394540942 180 17 0.0421836228287841 0
BRSK1-201 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0000086 Not Cancer Driver No 92 0.1182519280205655 461 53 0.0681233933161953 0
BRSK2-208 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0000086 Not Cancer Driver No 58 0.0788043478260869 321 23 0.03125 0
CALM1-201 CALM1 P0DP23 Calmodulin-1 chr14 GO:0000086 Not Cancer Driver No 12 0.0805369127516778 115 10 0.0671140939597315 6
CALM2-201 CALM1 P0DP23 Calmodulin-1 chr2 GO:0000086 Not Cancer Driver No 13 0.087248322147651 115 8 0.0536912751677852 6
CALM3-201 CALM1 P0DP23 Calmodulin-1 chr19 GO:0000086 Not Cancer Driver No 13 0.087248322147651 115 8 0.0536912751677852 6
CCDC57-202 CCDC57 Q2TAC2 Coiled-coil domain-containing protein 57 chr17 GO:0000086 Not Cancer Driver No 79 0.0863387978142076 604 44 0.048087431693989 0
CCNA2-201 CCNA2 P20248 Cyclin-A2 chr4 GO:0000086 Not Cancer Driver No 34 0.0787037037037037 187 14 0.0324074074074074 0
CCNB1-201 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0000086 Not Cancer Driver No 30 0.069284064665127 146 10 0.023094688221709 0
CCNY-203 CCNY Q8ND76 Cyclin-Y chr10 GO:0000086 Not Cancer Driver No 24 0.0703812316715542 94 5 0.0146627565982404 0
CDC25A-201 CDC25A P30304 M-phase inducer phosphatase 1 chr3 GO:0000086 Not Cancer Driver No 45 0.0858778625954198 314 27 0.0515267175572519 0
CDC25B-201 CDC25B P30305 M-phase inducer phosphatase 2 chr20 GO:0000086 Not Cancer Driver No 61 0.1051724137931034 329 33 0.0568965517241379 0
CDC25C-201 CDC25C P30307 M-phase inducer phosphatase 3 chr5 GO:0000086 Not Cancer Driver No 48 0.1014799154334038 226 19 0.040169133192389 0
CDK1-203 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0000086 Not Cancer Driver No 26 0.0875420875420875 1 0 0.0 0
CDK14-202 CDK14 O94921 Cyclin-dependent kinase 14 chr7 GO:0000086 Not Cancer Driver No 73 0.1556503198294243 154 12 0.0255863539445629 0
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0000086 Not Cancer Driver No 17 0.0570469798657718 0 0 0.0 0
CHEK1-204 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0000086 Not Cancer Driver No 42 0.088235294117647 86 13 0.0273109243697479 0
CHEK2-206 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0000086 Census, Compendium Yes 72 0.1325966850828729 157 19 0.0349907918968692 11
DNM2-201 DNM2 P50570 Dynamin-2 chr19 GO:0000086 Census Yes 95 0.1091954022988505 271 32 0.0367816091954023 16
ENSA-208 ENSA O43768 Alpha-endosulfine chr1 GO:0000086 Not Cancer Driver No 11 0.0909090909090909 121 11 0.0909090909090909 0
FBXL15-201 FBXL15 Q9H469 F-box/LRR-repeat protein 15 chr10 GO:0000086 Not Cancer Driver No 7 0.0233333333333333 16 0 0.0 0
FBXL7-202 FBXL7 Q9UJT9 F-box/LRR-repeat protein 7 chr5 GO:0000086 Not Cancer Driver No 178 0.3625254582484725 117 26 0.0529531568228105 0
FOXM1-202 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0000086 Not Cancer Driver No 73 0.0956749672346002 605 57 0.0747051114023591 0
KDM8-201 KDM8 Q8N371 Bifunctional peptidase and arginyl-hydroxylase JMJD5 chr16 GO:0000086 Not Cancer Driver No 32 0.0769230769230769 29 6 0.0144230769230769 0
KHDRBS1-202 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 GO:0000086 Not Cancer Driver No 42 0.0948081264108352 362 37 0.0835214446952596 0
LATS1-207 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0000086 Census, Compendium Yes 122 0.1079646017699115 790 74 0.0654867256637168 0
LCMT1-203 LCMT1 Q9UIC8 Leucine carboxyl methyltransferase 1 chr16 GO:0000086 Not Cancer Driver No 34 0.1017964071856287 2 0 0.0 0
MASTL-202 MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0000086 Not Cancer Driver No 68 0.0773606370875995 393 35 0.0398179749715585 0
MELK-201 MELK Q14680 Maternal embryonic leucine zipper kinase chr9 GO:0000086 Not Cancer Driver No 51 0.0783410138248847 164 18 0.0276497695852534 0
MTA3-201 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 GO:0000086 Not Cancer Driver No 38 0.0639730639730639 169 12 0.0202020202020202 0
NES-201 NES P48681 Nestin chr1 GO:0000086 Not Cancer Driver No 203 0.1252313386798272 1485 189 0.1165946946329426 0
PBX1-203 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0000086 Census Yes 64 0.1488372093023255 291 44 0.1023255813953488 0
PKMYT1-201 PKMYT1 Q99640 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase chr16 GO:0000086 Not Cancer Driver No 28 0.0561122244488977 228 14 0.0280561122244488 0
PLCB1-201 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0000086 Not Cancer Driver No 264 0.2171052631578947 484 85 0.0699013157894736 0
PLK1-201 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0000086 Not Cancer Driver No 68 0.1127694859038142 120 14 0.0232172470978441 0
PLK3-201 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0000086 Not Cancer Driver No 55 0.0851393188854489 203 11 0.0170278637770897 0
PPM1D-201 PPM1D O15297 Protein phosphatase 1D chr17 GO:0000086 Census, Compendium Yes 32 0.052892561983471 370 17 0.028099173553719 0
PPME1-201 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 GO:0000086 Not Cancer Driver No 28 0.0725388601036269 146 8 0.0207253886010362 0
SKP2-202 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 GO:0000086 Not Cancer Driver No 37 0.0872641509433962 52 5 0.0117924528301886 0
TAF2-201 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 GO:0000086 Not Cancer Driver No 83 0.0692243536280233 242 21 0.0175145954962468 1
TPD52L1-213 TPD52L1 Q16890 Tumor protein D53 chr6 GO:0000086 Not Cancer Driver No 33 0.1617647058823529 170 26 0.1274509803921568 0
UBE2A-202 UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:0000086 Compendium Yes 23 0.1513157894736842 67 11 0.0723684210526315 2
USH1C-202 USH1C Q9Y6N9 Harmonin chr11 GO:0000086 Not Cancer Driver No 79 0.1431159420289855 154 32 0.0579710144927536 0
WEE1-202 WEE1 P30291 Wee1-like protein kinase chr11 GO:0000086 Not Cancer Driver No 42 0.0650154798761609 399 20 0.0309597523219814 0
WNT10B-201 WNT10B O00744 Protein Wnt-10b chr12 GO:0000086 Not Cancer Driver No 45 0.1156812339331619 84 14 0.0359897172236503 2