Total number of protein in "GO:0000723" GO term: 57
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACD-212 | ACD | Q96AP0 | Adrenocortical dysplasia protein homolog | chr16 | GO:0000723 | Not Cancer Driver | No | 42 | 0.0917030567685589 | 257 | 31 | 0.0676855895196506 | 1 |
| ACTL6A-202 | ACTL6A | O96019 | Actin-like protein 6A | chr3 | GO:0000723 | Not Cancer Driver | No | 39 | 0.0909090909090909 | 74 | 8 | 0.0186480186480186 | 1 |
| ACTR5-201 | ACTR5 | Q9H9F9 | Actin-related protein 5 | chr20 | GO:0000723 | Not Cancer Driver | No | 42 | 0.0691927512355848 | 163 | 12 | 0.0197693574958813 | 0 |
| ACTR8-201 | ACTR8 | Q9H981 | Actin-related protein 8 | chr3 | GO:0000723 | Not Cancer Driver | No | 48 | 0.0769230769230769 | 240 | 18 | 0.0288461538461538 | 0 |
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0000723 | Not Cancer Driver | No | 23 | 0.0723270440251572 | 104 | 9 | 0.0283018867924528 | 0 |
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0000723 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| ATR-201 | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:0000723 | Census, Compendium | Yes | 261 | 0.098714069591528 | 107 | 11 | 0.0041603630862329 | 1 |
| BLM-201 | BLM | P54132 | RecQ-like DNA helicase BLM | chr15 | GO:0000723 | Census | Yes | 112 | 0.0790402258292166 | 671 | 53 | 0.0374029640084686 | 9 |
| CCNE1-201 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:0000723 | Census | Yes | 44 | 0.1073170731707317 | 142 | 15 | 0.0365853658536585 | 0 |
| CCNE2-201 | CCNE2 | O96020 | G1/S-specific cyclin-E2 | chr8 | GO:0000723 | Not Cancer Driver | No | 35 | 0.0866336633663366 | 69 | 9 | 0.0222772277227722 | 0 |
| CTC1-214 | CTC1 | Q2NKJ3 | CST complex subunit CTC1 | chr17 | GO:0000723 | Not Cancer Driver | No | 107 | 0.0879211175020542 | 106 | 4 | 0.0032867707477403 | 9 |
| DCLRE1B-203 | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0000723 | Not Cancer Driver | No | 44 | 0.0827067669172932 | 127 | 12 | 0.0225563909774436 | 1 |
| DCLRE1C-209 | DCLRE1C | Q96SD1 | Protein artemis | chr10 | GO:0000723 | Not Cancer Driver | No | 56 | 0.0809248554913294 | 277 | 21 | 0.0303468208092485 | 3 |
| DNA2-201 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0000723 | Not Cancer Driver | No | 72 | 0.0679245283018867 | 52 | 4 | 0.0037735849056603 | 3 |
| ENST00000640655 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0000723 | Not Cancer Driver | No | 92 | 0.0758450123660346 | 721 | 45 | 0.0370981038746908 | 0 |
| ERCC4-201 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0000723 | Census | Yes | 81 | 0.0884279475982532 | 226 | 19 | 0.0207423580786026 | 15 |
| HUS1-201 | HUS1 | O60921 | Checkpoint protein HUS1 | chr7 | GO:0000723 | Not Cancer Driver | No | 19 | 0.0678571428571428 | 17 | 1 | 0.0035714285714285 | 0 |
| HUS1B-201 | HUS1B | Q8NHY5 | Checkpoint protein HUS1B | chr6 | GO:0000723 | Not Cancer Driver | No | 35 | 0.1258992805755395 | 10 | 1 | 0.0035971223021582 | 0 |
| INO80-209 | INO80 | Q9ULG1 | Chromatin-remodeling ATPase INO80 | chr15 | GO:0000723 | Compendium | Yes | 137 | 0.0880462724935732 | 682 | 67 | 0.0430591259640102 | 0 |
| INO80B-201 | INO80B | Q9C086 | INO80 complex subunit B | chr2 | GO:0000723 | Not Cancer Driver | No | 24 | 0.0674157303370786 | 336 | 22 | 0.0617977528089887 | 0 |
| INO80B-WBP1-202 | INO80B | Q9C086 | INO80 complex subunit B | chr2 | GO:0000723 | Not Cancer Driver | No | 27 | 0.0743801652892562 | 337 | 25 | 0.0688705234159779 | 0 |
| INO80C-202 | INO80C | Q6PI98 | INO80 complex subunit C | chr18 | GO:0000723 | Not Cancer Driver | No | 17 | 0.0885416666666666 | 109 | 11 | 0.0572916666666666 | 0 |
| INO80D-201 | INO80D | Q53TQ3 | INO80 complex subunit D | chr2 | GO:0000723 | Not Cancer Driver | No | 84 | 0.0817916260954235 | 738 | 68 | 0.0662122687439143 | 0 |
| INO80E-207 | INO80E | Q8NBZ0 | INO80 complex subunit E | chr16 | GO:0000723 | Not Cancer Driver | No | 15 | 0.0614754098360655 | 211 | 15 | 0.0614754098360655 | 0 |
| LTO1-201 | LTO1 | Q8WV07 | Protein LTO1 homolog | chr11 | GO:0000723 | Not Cancer Driver | No | 14 | 0.1021897810218978 | 12 | 0 | 0.0 | 0 |
| MCRS1-201 | MCRS1 | Q96EZ8 | Microspherule protein 1 | chr12 | GO:0000723 | Not Cancer Driver | No | 47 | 0.1017316017316017 | 152 | 13 | 0.0281385281385281 | 0 |
| MRE11-201 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0000723 | Not Cancer Driver | No | 61 | 0.0861581920903954 | 292 | 28 | 0.03954802259887 | 1 |
| NBN-201 | NBN | O60934 | Nibrin | chr8 | GO:0000723 | Census | Yes | 63 | 0.0835543766578249 | 420 | 45 | 0.059681697612732 | 1 |
| NFRKB-212 | NFRKB | Q6P4R8 | Nuclear factor related to kappa-B-binding protein | chr11 | GO:0000723 | Not Cancer Driver | No | 54 | 0.0415704387990762 | 838 | 24 | 0.0184757505773672 | 0 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0000723 | Not Cancer Driver | No | 88 | 0.0867850098619329 | 322 | 28 | 0.0276134122287968 | 0 |
| PARP3-201 | PARP3 | Q9Y6F1 | Protein mono-ADP-ribosyltransferase PARP3 | chr3 | GO:0000723 | Not Cancer Driver | No | 48 | 0.0900562851782364 | 272 | 27 | 0.0506566604127579 | 0 |
| PRKDC-201 | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0000723 | Not Cancer Driver | No | 385 | 0.0932655038759689 | 421 | 43 | 0.0104166666666666 | 2 |
| PTGES3-201 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | GO:0000723 | Not Cancer Driver | No | 8 | 0.05 | 52 | 2 | 0.0125 | 0 |
| RAD50-201 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0000723 | Not Cancer Driver | No | 106 | 0.0807926829268292 | 730 | 50 | 0.0381097560975609 | 0 |
| RAD51D-202 | RAD51D | O75771 | DNA repair protein RAD51 homolog 4 | chr17 | GO:0000723 | Not Cancer Driver | No | 20 | 0.0609756097560975 | 50 | 8 | 0.024390243902439 | 0 |
| RECQL4-209 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | GO:0000723 | Census, Compendium | Yes | 105 | 0.0869205298013245 | 612 | 54 | 0.0447019867549668 | 1 |
| RIF1-205 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | GO:0000723 | Not Cancer Driver | No | 194 | 0.0784789644012945 | 1364 | 112 | 0.0453074433656957 | 0 |
| RPA1-201 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | GO:0000723 | Not Cancer Driver | No | 45 | 0.073051948051948 | 98 | 7 | 0.0113636363636363 | 1 |
| RPA2-203 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0000723 | Not Cancer Driver | No | 20 | 0.074074074074074 | 117 | 12 | 0.0444444444444444 | 0 |
| RPA3-201 | RPA3 | P35244 | Replication protein A 14 kDa subunit | chr7 | GO:0000723 | Not Cancer Driver | No | 10 | 0.0826446280991735 | 4 | 1 | 0.0082644628099173 | 0 |
| RTEL1-205 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:0000723 | Not Cancer Driver | No | 106 | 0.0869565217391304 | 479 | 50 | 0.0410172272354388 | 15 |
| RUVBL1-201 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | GO:0000723 | Not Cancer Driver | No | 41 | 0.0899122807017543 | 67 | 5 | 0.0109649122807017 | 0 |
| RUVBL2-206 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0000723 | Not Cancer Driver | No | 52 | 0.1123110151187904 | 100 | 11 | 0.0237580993520518 | 0 |
| SP100-201 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | GO:0000723 | Not Cancer Driver | No | 76 | 0.08646188850967 | 683 | 61 | 0.0693970420932878 | 0 |
| STN1-201 | STN1 | Q9H668 | CST complex subunit STN1 | chr10 | GO:0000723 | Not Cancer Driver | No | 34 | 0.092391304347826 | 27 | 3 | 0.0081521739130434 | 2 |
| TERF1-202 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | GO:0000723 | Not Cancer Driver | No | 51 | 0.1161731207289293 | 221 | 32 | 0.0728929384965831 | 0 |
| TERF2-201 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:0000723 | Not Cancer Driver | No | 26 | 0.047970479704797 | 361 | 15 | 0.0276752767527675 | 0 |
| TERF2IP-201 | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:0000723 | Not Cancer Driver | No | 20 | 0.050125313283208 | 312 | 12 | 0.0300751879699248 | 0 |
| TERT-201 | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:0000723 | Census | Yes | 86 | 0.0759717314487632 | 213 | 11 | 0.0097173144876325 | 32 |
| TFPT-203 | TFPT | P0C1Z6 | TCF3 fusion partner | chr19 | GO:0000723 | Census | Yes | 32 | 0.1264822134387351 | 237 | 31 | 0.1225296442687747 | 0 |
| UCHL5-206 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | GO:0000723 | Not Cancer Driver | No | 23 | 0.0699088145896656 | 41 | 2 | 0.0060790273556231 | 0 |
| WRN-201 | WRN | Q14191 | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | chr8 | GO:0000723 | Census, Compendium | Yes | 133 | 0.092877094972067 | 374 | 29 | 0.0202513966480446 | 2 |
| XRCC5-201 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0000723 | Not Cancer Driver | No | 53 | 0.0724043715846994 | 119 | 6 | 0.0081967213114754 | 0 |
| XRCC6-202 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0000723 | Not Cancer Driver | No | 49 | 0.0804597701149425 | 140 | 8 | 0.0131362889983579 | 0 |
| YY1-201 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | GO:0000723 | Not Cancer Driver | No | 29 | 0.0700483091787439 | 337 | 21 | 0.0507246376811594 | 2 |
| ZNF365-201 | ZNF365 | Q70YC5 | Protein ZNF365 | chr10 | GO:0000723 | Not Cancer Driver | No | 46 | 0.113022113022113 | 176 | 14 | 0.0343980343980344 | 0 |
| ZNF827-203 | ZNF827 | Q17R98 | Zinc finger protein 827 | chr4 | GO:0000723 | Not Cancer Driver | No | 117 | 0.1082331174838112 | 754 | 88 | 0.0814061054579093 | 0 |