Total number of protein in "GO:0000775" GO term: 56
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BIRC5-202 | BIRC5 | O15392 | Baculoviral IAP repeat-containing protein 5 | chr17 | GO:0000775 | Not Cancer Driver | No | 16 | 0.1126760563380281 | 51 | 4 | 0.028169014084507 | 0 |
| C1orf112-202 | FIRRM | Q9NSG2 | FIGNL1-interacting regulator of recombination and mitosis | chr1 | GO:0000775 | Not Cancer Driver | No | 64 | 0.0750293083235638 | 26 | 1 | 0.0011723329425556 | 0 |
| C9orf78-201 | C9orf78 | Q9NZ63 | Splicing factor C9orf78 | chr9 | GO:0000775 | Not Cancer Driver | No | 20 | 0.0692041522491349 | 286 | 20 | 0.0692041522491349 | 0 |
| CBX1-201 | CBX1 | P83916 | Chromobox protein homolog 1 | chr17 | GO:0000775 | Not Cancer Driver | No | 17 | 0.0918918918918919 | 155 | 14 | 0.0756756756756756 | 0 |
| CBX3-202 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | GO:0000775 | Not Cancer Driver | No | 18 | 0.0983606557377049 | 119 | 13 | 0.0710382513661202 | 0 |
| CDCA5-201 | CDCA5 | Q96FF9 | Sororin | chr11 | GO:0000775 | Not Cancer Driver | No | 24 | 0.0952380952380952 | 211 | 20 | 0.0793650793650793 | 0 |
| CDCA8-202 | CDCA8 | Q53HL2 | Borealin | chr1 | GO:0000775 | Not Cancer Driver | No | 18 | 0.0642857142857142 | 171 | 10 | 0.0357142857142857 | 0 |
| CENPA-202 | CENPA | P49450 | Histone H3-like centromeric protein A | chr2 | GO:0000775 | Not Cancer Driver | No | 12 | 0.0857142857142857 | 50 | 1 | 0.0071428571428571 | 0 |
| CENPB-201 | CENPB | P07199 | Major centromere autoantigen B | chr20 | GO:0000775 | Not Cancer Driver | No | 33 | 0.0550918196994991 | 374 | 16 | 0.026711185308848 | 0 |
| CENPE-201 | CENPE | Q02224 | Centromere-associated protein E | chr4 | GO:0000775 | Not Cancer Driver | No | 242 | 0.0895964457608293 | 1627 | 160 | 0.0592373195112921 | 2 |
| CENPF-201 | CENPF | P49454 | Centromere protein F | chr1 | GO:0000775 | Not Cancer Driver | No | 272 | 0.0873474630700064 | 2158 | 181 | 0.0581245985870263 | 0 |
| CENPT-208 | CENPT | Q96BT3 | Centromere protein T | chr16 | GO:0000775 | Not Cancer Driver | No | 49 | 0.0873440285204991 | 471 | 45 | 0.0802139037433155 | 0 |
| CENPW-203 | CENPW | Q5EE01 | Centromere protein W | chr6 | GO:0000775 | Not Cancer Driver | No | 7 | 0.0795454545454545 | 5 | 1 | 0.0113636363636363 | 0 |
| CTCF-201 | CTCF | P49711 | Transcriptional repressor CTCF | chr16 | GO:0000775 | Census, Compendium | Yes | 122 | 0.1678129298486932 | 482 | 62 | 0.0852819807427785 | 1 |
| DAXX-202 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | GO:0000775 | Census, Compendium | Yes | 79 | 0.1067567567567567 | 549 | 57 | 0.077027027027027 | 0 |
| DNMT3A-202 | DNMT3A | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | chr2 | GO:0000775 | Census, Compendium | Yes | 143 | 0.156798245614035 | 372 | 44 | 0.0482456140350877 | 14 |
| DSCC1-201 | DSCC1 | Q9BVC3 | Sister chromatid cohesion protein DCC1 | chr8 | GO:0000775 | Not Cancer Driver | No | 14 | 0.0356234096692111 | 41 | 2 | 0.005089058524173 | 0 |
| FMR1-205 | FMR1 | Q06787 | Fragile X messenger ribonucleoprotein 1 | chrX | GO:0000775 | Not Cancer Driver | No | 92 | 0.1455696202531645 | 327 | 50 | 0.0791139240506329 | 3 |
| HELLS-201 | HELLS | Q9NRZ9 | Lymphoid-specific helicase | chr10 | GO:0000775 | Not Cancer Driver | No | 52 | 0.0620525059665871 | 228 | 16 | 0.0190930787589498 | 0 |
| HJURP-202 | HJURP | Q8NCD3 | Holliday junction recognition protein | chr2 | GO:0000775 | Not Cancer Driver | No | 84 | 0.1122994652406417 | 580 | 65 | 0.0868983957219251 | 0 |
| INCENP-202 | INCENP | Q9NQS7 | Inner centromere protein | chr11 | GO:0000775 | Not Cancer Driver | No | 65 | 0.0708061002178649 | 863 | 63 | 0.0686274509803921 | 0 |
| KAT7-201 | KAT7 | O95251 | Histone acetyltransferase KAT7 | chr17 | GO:0000775 | Census | Yes | 64 | 0.1047463175122749 | 327 | 27 | 0.044189852700491 | 0 |
| KIF2C-202 | KIF2C | Q99661 | Kinesin-like protein KIF2C | chr1 | GO:0000775 | Not Cancer Driver | No | 82 | 0.113103448275862 | 338 | 48 | 0.0662068965517241 | 0 |
| MIS18A-201 | MIS18A | Q9NYP9 | Protein Mis18-alpha | chr21 | GO:0000775 | Not Cancer Driver | No | 16 | 0.0686695278969957 | 15 | 1 | 0.0042918454935622 | 0 |
| MIS18BP1-201 | MIS18BP1 | Q6P0N0 | Mis18-binding protein 1 | chr14 | GO:0000775 | Not Cancer Driver | No | 81 | 0.0715547703180212 | 850 | 63 | 0.0556537102473498 | 0 |
| NDC80-201 | NDC80 | O14777 | Kinetochore protein NDC80 homolog | chr18 | GO:0000775 | Not Cancer Driver | No | 58 | 0.0903426791277258 | 313 | 34 | 0.0529595015576324 | 0 |
| NGDN-202 | NGDN | Q8NEJ9 | Neuroguidin | chr14 | GO:0000775 | Not Cancer Driver | No | 21 | 0.0666666666666666 | 195 | 14 | 0.0444444444444444 | 0 |
| OIP5-201 | OIP5 | O43482 | Protein Mis18-beta | chr15 | GO:0000775 | Not Cancer Driver | No | 26 | 0.1135371179039301 | 65 | 6 | 0.0262008733624454 | 0 |
| PDS5A-201 | PDS5A | Q29RF7 | Sister chromatid cohesion protein PDS5 homolog A | chr4 | GO:0000775 | Not Cancer Driver | No | 101 | 0.075542258788332 | 295 | 28 | 0.0209424083769633 | 0 |
| PDS5B-201 | PDS5B | Q9NTI5 | Sister chromatid cohesion protein PDS5 homolog B | chr13 | GO:0000775 | Not Cancer Driver | No | 127 | 0.0877677954388389 | 455 | 45 | 0.0310988251554941 | 0 |
| PKHD1-202 | PKHD1 | P08F94 | Fibrocystin | chr6 | GO:0000775 | Not Cancer Driver | No | 610 | 0.1497299950908198 | 415 | 62 | 0.0152184585174275 | 91 |
| PPP2CA-203 | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | GO:0000775 | Not Cancer Driver | No | 32 | 0.1035598705501618 | 12 | 1 | 0.0032362459546925 | 7 |
| PPP2CB-201 | PPP2CB | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | chr8 | GO:0000775 | Not Cancer Driver | No | 27 | 0.087378640776699 | 12 | 0 | 0.0 | 0 |
| PPP2R1A-201 | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | GO:0000775 | Census, Compendium | Yes | 169 | 0.2869269949066214 | 0 | 0 | 0.0 | 4 |
| PPP2R5A-201 | PPP2R5A | Q15172 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | chr1 | GO:0000775 | Not Cancer Driver | No | 31 | 0.0637860082304526 | 93 | 2 | 0.0041152263374485 | 0 |
| PPP2R5C-202 | PPP2R5C | Q13362 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | chr14 | GO:0000775 | Not Cancer Driver | No | 48 | 0.0916030534351145 | 89 | 15 | 0.0286259541984732 | 0 |
| RAD21-201 | RAD21 | O60216 | Double-strand-break repair protein rad21 homolog | chr8 | GO:0000775 | Census, Compendium | Yes | 84 | 0.1331220285261489 | 421 | 56 | 0.0887480190174326 | 3 |
| SGO1-201 | SGO1 | Q5FBB7 | Shugoshin 1 | chr3 | GO:0000775 | Not Cancer Driver | No | 45 | 0.0802139037433155 | 361 | 29 | 0.0516934046345811 | 1 |
| SGO2-201 | SGO2 | Q562F6 | Shugoshin 2 | chr2 | GO:0000775 | Not Cancer Driver | No | 111 | 0.0877470355731225 | 1029 | 91 | 0.0719367588932806 | 0 |
| SMC1A-201 | SMC1A | Q14683 | Structural maintenance of chromosomes protein 1A | chrX | GO:0000775 | Census, Compendium | Yes | 142 | 0.1151662611516626 | 717 | 83 | 0.0673154906731549 | 17 |
| SMC1B-201 | SMC1B | Q8NDV3 | Structural maintenance of chromosomes protein 1B | chr22 | GO:0000775 | Not Cancer Driver | No | 101 | 0.0817813765182186 | 362 | 29 | 0.0234817813765182 | 0 |
| SMC3-201 | SMC3 | Q9UQE7 | Structural maintenance of chromosomes protein 3 | chr10 | GO:0000775 | Not Cancer Driver | No | 116 | 0.09531635168447 | 605 | 49 | 0.0402629416598192 | 0 |
| SMC4-202 | SMC4 | Q9NTJ3 | Structural maintenance of chromosomes protein 4 | chr3 | GO:0000775 | Not Cancer Driver | No | 136 | 0.1055900621118012 | 539 | 40 | 0.031055900621118 | 0 |
| SMC5-201 | SMC5 | Q8IY18 | Structural maintenance of chromosomes protein 5 | chr9 | GO:0000775 | Not Cancer Driver | No | 94 | 0.0853769300635785 | 381 | 35 | 0.0317892824704813 | 1 |
| SMC6-207 | SMC6 | Q96SB8 | Structural maintenance of chromosomes protein 6 | chr2 | GO:0000775 | Not Cancer Driver | No | 95 | 0.0870760769935838 | 459 | 43 | 0.0394133822181484 | 0 |
| STAG1-202 | STAG1 | Q8WVM7 | Cohesin subunit SA-1 | chr3 | GO:0000775 | Census | Yes | 166 | 0.1319554848966613 | 391 | 48 | 0.0381558028616852 | 8 |
| STAG2-211 | STAG2 | Q8N3U4 | Cohesin subunit SA-2 | chrX | GO:0000775 | Census, Compendium | Yes | 123 | 0.099918765231519 | 331 | 31 | 0.025182778229082 | 3 |
| STAG3-201 | STAG3 | Q9UJ98 | Cohesin subunit SA-3 | chr7 | GO:0000775 | Not Cancer Driver | No | 121 | 0.0987755102040816 | 388 | 42 | 0.0342857142857142 | 3 |
| SUV39H1-202 | SUV39H1 | O43463 | Histone-lysine N-methyltransferase SUV39H1 | chrX | GO:0000775 | Not Cancer Driver | No | 43 | 0.1043689320388349 | 15 | 1 | 0.0024271844660194 | 0 |
| SUV39H2-202 | SUV39H2 | Q9H5I1 | Histone-lysine N-methyltransferase SUV39H2 | chr10 | GO:0000775 | Not Cancer Driver | No | 28 | 0.0682926829268292 | 23 | 1 | 0.0024390243902439 | 0 |
| SYCP1-202 | SYCP1 | Q15431 | Synaptonemal complex protein 1 | chr1 | GO:0000775 | Not Cancer Driver | No | 147 | 0.1506147540983606 | 604 | 80 | 0.081967213114754 | 0 |
| SYCP3-202 | SYCP3 | Q8IZU3 | Synaptonemal complex protein 3 | chr12 | GO:0000775 | Not Cancer Driver | No | 23 | 0.097457627118644 | 124 | 8 | 0.0338983050847457 | 0 |
| TOP2A-201 | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | GO:0000775 | Compendium | Yes | 115 | 0.0751143043762246 | 509 | 46 | 0.0300457217504898 | 0 |
| UVRAG-201 | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0000775 | Not Cancer Driver | No | 58 | 0.0829756795422031 | 243 | 21 | 0.0300429184549356 | 0 |
| WAPL-201 | WAPL | Q7Z5K2 | Wings apart-like protein homolog | chr10 | GO:0000775 | Not Cancer Driver | No | 104 | 0.0873949579831932 | 623 | 49 | 0.0411764705882352 | 0 |
| ZNF330-201 | ZNF330 | Q9Y3S2 | Zinc finger protein 330 | chr4 | GO:0000775 | Not Cancer Driver | No | 31 | 0.096875 | 127 | 14 | 0.04375 | 0 |