Total number of protein in "GO:0000781" GO term: 171
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACD-212 | ACD | Q96AP0 | Adrenocortical dysplasia protein homolog | chr16 | GO:0000781 | Not Cancer Driver | No | 42 | 0.0917030567685589 | 257 | 31 | 0.0676855895196506 | 1 |
| ALYREF-202 | ALYREF | Q86V81 | THO complex subunit 4 | chr17 | GO:0000781 | Not Cancer Driver | No | 30 | 0.1136363636363636 | 230 | 26 | 0.0984848484848484 | 0 |
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0000781 | Not Cancer Driver | No | 23 | 0.0723270440251572 | 104 | 9 | 0.0283018867924528 | 0 |
| ATF7-201 | ATF7 | P17544 | Cyclic AMP-dependent transcription factor ATF-7 | chr12 | GO:0000781 | Not Cancer Driver | No | 36 | 0.0745341614906832 | 468 | 36 | 0.0745341614906832 | 0 |
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0000781 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| ATR-201 | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | GO:0000781 | Census, Compendium | Yes | 261 | 0.098714069591528 | 107 | 11 | 0.0041603630862329 | 1 |
| ATRX-201 | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0000781 | Census, Compendium | Yes | 306 | 0.1227929373996789 | 1673 | 173 | 0.069422150882825 | 29 |
| BLM-201 | BLM | P54132 | RecQ-like DNA helicase BLM | chr15 | GO:0000781 | Census | Yes | 112 | 0.0790402258292166 | 671 | 53 | 0.0374029640084686 | 9 |
| BRCA2-201 | BRCA2 | P51587 | Breast cancer type 2 susceptibility protein | chr13 | GO:0000781 | Census, Compendium | Yes | 310 | 0.0906963136337039 | 1545 | 152 | 0.0444704505558806 | 46 |
| CBX1-201 | CBX1 | P83916 | Chromobox protein homolog 1 | chr17 | GO:0000781 | Not Cancer Driver | No | 17 | 0.0918918918918919 | 155 | 14 | 0.0756756756756756 | 0 |
| CBX3-202 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | GO:0000781 | Not Cancer Driver | No | 18 | 0.0983606557377049 | 119 | 13 | 0.0710382513661202 | 0 |
| CBX5-201 | CBX5 | P45973 | Chromobox protein homolog 5 | chr12 | GO:0000781 | Not Cancer Driver | No | 15 | 0.0785340314136125 | 116 | 8 | 0.0418848167539267 | 0 |
| CDC73-201 | CDC73 | Q6P1J9 | Parafibromin | chr1 | GO:0000781 | Census, Compendium | Yes | 78 | 0.1468926553672316 | 210 | 32 | 0.0602636534839924 | 2 |
| CDK1-203 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0000781 | Not Cancer Driver | No | 26 | 0.0875420875420875 | 1 | 0 | 0.0 | 0 |
| CDK2-201 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0000781 | Not Cancer Driver | No | 17 | 0.0570469798657718 | 0 | 0 | 0.0 | 0 |
| CHD4-206 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | GO:0000781 | Census, Compendium | Yes | 312 | 0.1631799163179916 | 978 | 118 | 0.0617154811715481 | 6 |
| CHEK1-204 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0000781 | Not Cancer Driver | No | 42 | 0.088235294117647 | 86 | 13 | 0.0273109243697479 | 0 |
| CHEK2-206 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:0000781 | Census, Compendium | Yes | 72 | 0.1325966850828729 | 157 | 19 | 0.0349907918968692 | 11 |
| CTC1-214 | CTC1 | Q2NKJ3 | CST complex subunit CTC1 | chr17 | GO:0000781 | Not Cancer Driver | No | 107 | 0.0879211175020542 | 106 | 4 | 0.0032867707477403 | 9 |
| DCLRE1B-203 | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0000781 | Not Cancer Driver | No | 44 | 0.0827067669172932 | 127 | 12 | 0.0225563909774436 | 1 |
| DDB1-201 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0000781 | Not Cancer Driver | No | 98 | 0.0859649122807017 | 50 | 8 | 0.0070175438596491 | 3 |
| DHX36-213 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:0000781 | Not Cancer Driver | No | 110 | 0.1091269841269841 | 223 | 27 | 0.0267857142857142 | 0 |
| DMC1-201 | DMC1 | Q14565 | Meiotic recombination protein DMC1/LIM15 homolog | chr22 | GO:0000781 | Not Cancer Driver | No | 28 | 0.0823529411764705 | 49 | 5 | 0.0147058823529411 | 0 |
| DNA2-201 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0000781 | Not Cancer Driver | No | 72 | 0.0679245283018867 | 52 | 4 | 0.0037735849056603 | 3 |
| EID3-201 | EID3 | Q8N140 | EP300-interacting inhibitor of differentiation 3 | chr12 | GO:0000781 | Not Cancer Driver | No | 18 | 0.054054054054054 | 56 | 2 | 0.006006006006006 | 0 |
| ENST00000640655 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0000781 | Not Cancer Driver | No | 92 | 0.0758450123660346 | 721 | 45 | 0.0370981038746908 | 0 |
| ERCC1-202 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0000781 | Not Cancer Driver | No | 36 | 0.1212121212121212 | 107 | 14 | 0.0471380471380471 | 1 |
| ERCC4-201 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0000781 | Census | Yes | 81 | 0.0884279475982532 | 226 | 19 | 0.0207423580786026 | 15 |
| EZH1-202 | EZH1 | Q92800 | Histone-lysine N-methyltransferase EZH1 | chr17 | GO:0000781 | Not Cancer Driver | No | 60 | 0.0803212851405622 | 213 | 18 | 0.0240963855421686 | 0 |
| EZH2-203 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0000781 | Census, Compendium | Yes | 74 | 0.099195710455764 | 284 | 32 | 0.0428954423592493 | 11 |
| FEN1-201 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0000781 | Census | Yes | 29 | 0.0763157894736842 | 111 | 13 | 0.0342105263157894 | 0 |
| GAR1-201 | GAR1 | Q9NY12 | H/ACA ribonucleoprotein complex subunit 1 | chr4 | GO:0000781 | Not Cancer Driver | No | 5 | 0.0230414746543778 | 141 | 0 | 0.0 | 0 |
| GATAD2B-201 | GATAD2B | Q8WXI9 | Transcriptional repressor p66-beta | chr1 | GO:0000781 | Not Cancer Driver | No | 62 | 0.1045531197301855 | 510 | 57 | 0.0961214165261382 | 0 |
| H2AC1-201 | H2AC1 | Q96QV6 | Histone H2A type 1-A | chr6 | GO:0000781 | Not Cancer Driver | No | 22 | 0.1679389312977099 | 60 | 6 | 0.0458015267175572 | 0 |
| H2AX-202 | H2AX | P16104 | Histone H2AX | chr11 | GO:0000781 | Not Cancer Driver | No | 19 | 0.1328671328671328 | 68 | 8 | 0.0559440559440559 | 0 |
| H2BC1-201 | H2BC1 | Q96A08 | Histone H2B type 1-A | chr6 | GO:0000781 | Not Cancer Driver | No | 19 | 0.1496062992125984 | 59 | 10 | 0.0787401574803149 | 0 |
| H2BC3-201 | H2BC3 | P33778 | Histone H2B type 1-B | chr6 | GO:0000781 | Not Cancer Driver | No | 30 | 0.238095238095238 | 76 | 18 | 0.1428571428571428 | 0 |
| H3-3A-203 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0000781 | Not Cancer Driver | No | 27 | 0.1985294117647058 | 51 | 21 | 0.1544117647058823 | 18 |
| H3-3B-201 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0000781 | Not Cancer Driver | No | 26 | 0.1911764705882352 | 51 | 14 | 0.1029411764705882 | 18 |
| H3-4-201 | H3-4 | Q16695 | Histone H3.1t | chr1 | GO:0000781 | Not Cancer Driver | No | 25 | 0.1838235294117647 | 53 | 7 | 0.0514705882352941 | 0 |
| H4C1-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 6 | 0.058252427184466 | 32 | 0 | 0.0 | 11 |
| H4C11-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 18 | 0.174757281553398 | 31 | 2 | 0.0194174757281553 | 11 |
| H4C12-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 27 | 0.2621359223300971 | 32 | 1 | 0.0097087378640776 | 11 |
| H4C13-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 17 | 0.1650485436893204 | 31 | 4 | 0.0388349514563106 | 11 |
| H4C14-201 | H4C16 | P62805 | Histone H4 | chr1 | GO:0000781 | Not Cancer Driver | No | 0 | 0.0 | 31 | 0 | 0.0 | 11 |
| H4C15-201 | H4C16 | P62805 | Histone H4 | chr1 | GO:0000781 | Not Cancer Driver | No | 0 | 0.0 | 31 | 0 | 0.0 | 11 |
| H4C16-204 | H4C16 | P62805 | Histone H4 | chr12 | GO:0000781 | Not Cancer Driver | No | 15 | 0.145631067961165 | 31 | 2 | 0.0194174757281553 | 12 |
| H4C2-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 25 | 0.2427184466019417 | 32 | 3 | 0.029126213592233 | 11 |
| H4C3-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 24 | 0.233009708737864 | 31 | 2 | 0.0194174757281553 | 11 |
| H4C4-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 26 | 0.2524271844660194 | 31 | 1 | 0.0097087378640776 | 11 |
| H4C5-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 29 | 0.2815533980582524 | 31 | 4 | 0.0388349514563106 | 11 |
| H4C6-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 18 | 0.174757281553398 | 31 | 1 | 0.0097087378640776 | 11 |
| H4C8-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 13 | 0.1262135922330097 | 32 | 2 | 0.0194174757281553 | 11 |
| H4C9-201 | H4C16 | P62805 | Histone H4 | chr6 | GO:0000781 | Not Cancer Driver | No | 26 | 0.2524271844660194 | 31 | 4 | 0.0388349514563106 | 11 |
| HAT1-201 | HAT1 | O14929 | Histone acetyltransferase type B catalytic subunit | chr2 | GO:0000781 | Not Cancer Driver | No | 33 | 0.0787589498806682 | 14 | 1 | 0.0023866348448687 | 0 |
| HDAC2-205 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | GO:0000781 | Not Cancer Driver | No | 34 | 0.0696721311475409 | 145 | 11 | 0.0225409836065573 | 0 |
| HMBOX1-201 | HMBOX1 | Q6NT76 | Homeobox-containing protein 1 | chr8 | GO:0000781 | Not Cancer Driver | No | 36 | 0.0857142857142857 | 319 | 28 | 0.0666666666666666 | 0 |
| HNRNPA2B1-201 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | GO:0000781 | Census, Compendium | Yes | 35 | 0.0991501416430594 | 255 | 13 | 0.036827195467422 | 1 |
| KASH5-201 | KASH5 | Q8N6L0 | Protein KASH5 | chr19 | GO:0000781 | Not Cancer Driver | No | 73 | 0.1298932384341637 | 408 | 58 | 0.1032028469750889 | 0 |
| KDM1A-201 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0000781 | Not Cancer Driver | No | 48 | 0.056338028169014 | 291 | 21 | 0.0246478873239436 | 3 |
| LIG4-202 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0000781 | Not Cancer Driver | No | 103 | 0.1130625686059275 | 63 | 10 | 0.0109769484083424 | 2 |
| LRIF1-201 | LRIF1 | Q5T3J3 | Ligand-dependent nuclear receptor-interacting factor 1 | chr1 | GO:0000781 | Not Cancer Driver | No | 76 | 0.0988296488946684 | 520 | 45 | 0.0585175552665799 | 0 |
| LRWD1-201 | LRWD1 | Q9UFC0 | Leucine-rich repeat and WD repeat-containing protein 1 | chr7 | GO:0000781 | Not Cancer Driver | No | 46 | 0.071097372488408 | 133 | 9 | 0.0139103554868624 | 0 |
| MACROH2A1-202 | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:0000781 | Not Cancer Driver | No | 31 | 0.084010840108401 | 122 | 9 | 0.024390243902439 | 0 |
| MACROH2A2-201 | MACROH2A2 | Q9P0M6 | Core histone macro-H2A.2 | chr10 | GO:0000781 | Not Cancer Driver | No | 44 | 0.1182795698924731 | 171 | 23 | 0.0618279569892473 | 0 |
| MAJIN-204 | MAJIN | Q3KP22 | Membrane-anchored junction protein | chr11 | GO:0000781 | Not Cancer Driver | No | 6 | 0.034090909090909 | 143 | 4 | 0.0227272727272727 | 0 |
| MCM2-201 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | GO:0000781 | Not Cancer Driver | No | 77 | 0.0851769911504424 | 277 | 33 | 0.036504424778761 | 1 |
| MCM3-205 | MCM3 | P25205 | DNA replication licensing factor MCM3 | chr6 | GO:0000781 | Not Cancer Driver | No | 58 | 0.0717821782178217 | 310 | 28 | 0.0346534653465346 | 0 |
| MCM4-222 | MCM4 | P33991 | DNA replication licensing factor MCM4 | chr8 | GO:0000781 | Not Cancer Driver | No | 93 | 0.1077636152954808 | 215 | 29 | 0.033603707995365 | 0 |
| MCM5-201 | MCM5 | P33992 | DNA replication licensing factor MCM5 | chr22 | GO:0000781 | Not Cancer Driver | No | 68 | 0.0926430517711171 | 110 | 15 | 0.0204359673024523 | 1 |
| MCM6-201 | MCM6 | Q14566 | DNA replication licensing factor MCM6 | chr2 | GO:0000781 | Not Cancer Driver | No | 78 | 0.0950060901339829 | 122 | 11 | 0.0133982947624847 | 0 |
| MCM7-201 | MCM7 | P33993 | DNA replication licensing factor MCM7 | chr7 | GO:0000781 | Not Cancer Driver | No | 75 | 0.1043115438108484 | 128 | 16 | 0.0222531293463143 | 0 |
| MEN1-203 | MEN1 | O00255 | Menin | chr11 | GO:0000781 | Census, Compendium | Yes | 50 | 0.08130081300813 | 230 | 9 | 0.0146341463414634 | 80 |
| MRE11-201 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0000781 | Not Cancer Driver | No | 61 | 0.0861581920903954 | 292 | 28 | 0.03954802259887 | 1 |
| MSH2-201 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0000781 | Census | Yes | 55 | 0.0588865096359743 | 37 | 1 | 0.0010706638115631 | 63 |
| MTA2-201 | MTA2 | O94776 | Metastasis-associated protein MTA2 | chr11 | GO:0000781 | Not Cancer Driver | No | 59 | 0.0883233532934131 | 283 | 25 | 0.0374251497005988 | 0 |
| NABP1-205 | NABP1 | Q96AH0 | SOSS complex subunit B2 | chr2 | GO:0000781 | Not Cancer Driver | No | 20 | 0.0980392156862745 | 102 | 8 | 0.0392156862745098 | 0 |
| NABP2-201 | NABP2 | Q9BQ15 | SOSS complex subunit B1 | chr12 | GO:0000781 | Not Cancer Driver | No | 22 | 0.1042654028436018 | 125 | 14 | 0.0663507109004739 | 0 |
| NAT10-201 | NAT10 | Q9H0A0 | RNA cytidine acetyltransferase | chr11 | GO:0000781 | Not Cancer Driver | No | 75 | 0.073170731707317 | 142 | 9 | 0.008780487804878 | 0 |
| NBN-201 | NBN | O60934 | Nibrin | chr8 | GO:0000781 | Census | Yes | 63 | 0.0835543766578249 | 420 | 45 | 0.059681697612732 | 1 |
| NHP2-201 | NHP2 | Q9NX24 | H/ACA ribonucleoprotein complex subunit 2 | chr5 | GO:0000781 | Not Cancer Driver | No | 20 | 0.130718954248366 | 20 | 4 | 0.0261437908496732 | 2 |
| NLRP2-208 | NLRP2 | Q9NX02 | NACHT, LRR and PYD domains-containing protein 2 | chr19 | GO:0000781 | Not Cancer Driver | No | 207 | 0.1949152542372881 | 60 | 12 | 0.0112994350282485 | 0 |
| NSMCE1-201 | NSMCE1 | Q8WV22 | Non-structural maintenance of chromosomes element 1 homolog | chr16 | GO:0000781 | Not Cancer Driver | No | 21 | 0.0789473684210526 | 31 | 2 | 0.0075187969924812 | 0 |
| NSMCE2-201 | NSMCE2 | Q96MF7 | E3 SUMO-protein ligase NSE2 | chr8 | GO:0000781 | Not Cancer Driver | No | 18 | 0.0728744939271255 | 119 | 10 | 0.0404858299595141 | 0 |
| NSMCE3-201 | NSMCE3 | Q96MG7 | Non-structural maintenance of chromosomes element 3 homolog | chr15 | GO:0000781 | Not Cancer Driver | No | 24 | 0.0789473684210526 | 129 | 6 | 0.0197368421052631 | 2 |
| NSMCE4A-202 | NSMCE4A | Q9NXX6 | Non-structural maintenance of chromosomes element 4 homolog A | chr10 | GO:0000781 | Not Cancer Driver | No | 10 | 0.0259740259740259 | 201 | 2 | 0.0051948051948051 | 0 |
| ORC1-202 | ORC1 | Q13415 | Origin recognition complex subunit 1 | chr1 | GO:0000781 | Not Cancer Driver | No | 72 | 0.0836236933797909 | 340 | 30 | 0.0348432055749128 | 5 |
| ORC2-201 | ORC2 | Q13416 | Origin recognition complex subunit 2 | chr2 | GO:0000781 | Not Cancer Driver | No | 44 | 0.0762564991334488 | 249 | 13 | 0.022530329289428 | 0 |
| ORC3-202 | ORC3 | Q9UBD5 | Origin recognition complex subunit 3 | chr6 | GO:0000781 | Not Cancer Driver | No | 45 | 0.0632911392405063 | 64 | 4 | 0.0056258790436005 | 0 |
| ORC4-202 | ORC4 | O43929 | Origin recognition complex subunit 4 | chr2 | GO:0000781 | Not Cancer Driver | No | 36 | 0.0825688073394495 | 14 | 1 | 0.0022935779816513 | 1 |
| ORC5-201 | ORC5 | O43913 | Origin recognition complex subunit 5 | chr7 | GO:0000781 | Not Cancer Driver | No | 27 | 0.0620689655172413 | 16 | 2 | 0.0045977011494252 | 0 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0000781 | Not Cancer Driver | No | 88 | 0.0867850098619329 | 322 | 28 | 0.0276134122287968 | 0 |
| PCNA-201 | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0000781 | Not Cancer Driver | No | 19 | 0.0727969348659003 | 22 | 2 | 0.0076628352490421 | 1 |
| PIF1-205 | PIF1 | Q9H611 | ATP-dependent DNA helicase PIF1 | chr15 | GO:0000781 | Not Cancer Driver | No | 44 | 0.0686427457098284 | 210 | 9 | 0.0140405616224648 | 0 |
| PINX1-201 | PINX1 | Q96BK5 | PIN2/TERF1-interacting telomerase inhibitor 1 | chr8 | GO:0000781 | Not Cancer Driver | No | 37 | 0.1128048780487804 | 329 | 38 | 0.1158536585365853 | 0 |
| PML-201 | PML | P29590 | Protein PML | chr15 | GO:0000781 | Census, Compendium | Yes | 87 | 0.0986394557823129 | 312 | 28 | 0.0317460317460317 | 0 |
| POLD1-201 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | GO:0000781 | Census, Compendium | Yes | 118 | 0.1065943992773261 | 210 | 17 | 0.015356820234869 | 2 |
| POLR2B-201 | POLR2B | P30876 | DNA-directed RNA polymerase II subunit RPB2 | chr4 | GO:0000781 | Not Cancer Driver | No | 116 | 0.0988074957410562 | 173 | 17 | 0.014480408858603 | 0 |
| POT1-201 | POT1 | Q9NUX5 | Protection of telomeres protein 1 | chr7 | GO:0000781 | Census, Compendium | Yes | 98 | 0.1545741324921135 | 31 | 5 | 0.0078864353312302 | 9 |
| PPP1CA-203 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | GO:0000781 | Not Cancer Driver | No | 31 | 0.0939393939393939 | 27 | 6 | 0.0181818181818181 | 0 |
| PPP1CB-202 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | GO:0000781 | Not Cancer Driver | No | 33 | 0.1009174311926605 | 25 | 4 | 0.0122324159021406 | 4 |
| PPP1CC-201 | PPP1CC | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | chr12 | GO:0000781 | Not Cancer Driver | No | 19 | 0.0588235294117647 | 23 | 3 | 0.0092879256965944 | 0 |
| PPP1R10-201 | PPP1R10 | Q96QC0 | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | chr6 | GO:0000781 | Not Cancer Driver | No | 50 | 0.0531914893617021 | 798 | 40 | 0.0425531914893617 | 0 |
| PRKDC-201 | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0000781 | Not Cancer Driver | No | 385 | 0.0932655038759689 | 421 | 43 | 0.0104166666666666 | 2 |
| PTGES3-201 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | GO:0000781 | Not Cancer Driver | No | 8 | 0.05 | 52 | 2 | 0.0125 | 0 |
| PURA-201 | PURA | Q00577 | Transcriptional activator protein Pur-alpha | chr5 | GO:0000781 | Not Cancer Driver | No | 17 | 0.0527950310559006 | 188 | 6 | 0.0186335403726708 | 6 |
| RAD17-208 | RAD17 | O75943 | Cell cycle checkpoint protein RAD17 | chr5 | GO:0000781 | Census | Yes | 53 | 0.0778267254038179 | 207 | 12 | 0.0176211453744493 | 0 |
| RAD50-201 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0000781 | Not Cancer Driver | No | 106 | 0.0807926829268292 | 730 | 50 | 0.0381097560975609 | 0 |
| RAD51-201 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0000781 | Not Cancer Driver | No | 27 | 0.079646017699115 | 48 | 3 | 0.0088495575221238 | 3 |
| RAD51AP1-201 | RAD51AP1 | Q96B01 | RAD51-associated protein 1 | chr12 | GO:0000781 | Not Cancer Driver | No | 37 | 0.1051136363636363 | 337 | 35 | 0.0994318181818181 | 0 |
| RAD51D-202 | RAD51D | O75771 | DNA repair protein RAD51 homolog 4 | chr17 | GO:0000781 | Not Cancer Driver | No | 20 | 0.0609756097560975 | 50 | 8 | 0.024390243902439 | 0 |
| RBBP4-202 | RBBP4 | Q09028 | Histone-binding protein RBBP4 | chr1 | GO:0000781 | Not Cancer Driver | No | 40 | 0.0941176470588235 | 169 | 19 | 0.0447058823529411 | 0 |
| RBBP7-203 | RBBP7 | Q16576 | Histone-binding protein RBBP7 | chrX | GO:0000781 | Not Cancer Driver | No | 42 | 0.0988235294117647 | 138 | 8 | 0.0188235294117647 | 0 |
| RECQL4-209 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | GO:0000781 | Census, Compendium | Yes | 105 | 0.0869205298013245 | 612 | 54 | 0.0447019867549668 | 1 |
| RNF8-202 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0000781 | Not Cancer Driver | No | 31 | 0.0639175257731958 | 226 | 14 | 0.0288659793814433 | 0 |
| RPA1-201 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | GO:0000781 | Not Cancer Driver | No | 45 | 0.073051948051948 | 98 | 7 | 0.0113636363636363 | 1 |
| RPA2-203 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0000781 | Not Cancer Driver | No | 20 | 0.074074074074074 | 117 | 12 | 0.0444444444444444 | 0 |
| RPA4-201 | RPA4 | Q13156 | Replication protein A 30 kDa subunit | chrX | GO:0000781 | Not Cancer Driver | No | 56 | 0.21455938697318 | 59 | 10 | 0.0383141762452107 | 0 |
| RTEL1-205 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:0000781 | Not Cancer Driver | No | 106 | 0.0869565217391304 | 479 | 50 | 0.0410172272354388 | 15 |
| SETX-201 | SETX | Q7Z333 | Probable helicase senataxin | chr9 | GO:0000781 | Not Cancer Driver | No | 213 | 0.0795666791184161 | 1248 | 89 | 0.0332461710870377 | 19 |
| SIRT2-201 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0000781 | Not Cancer Driver | No | 40 | 0.1028277634961439 | 85 | 13 | 0.0334190231362467 | 0 |
| SLF1-201 | SLF1 | Q9BQI6 | SMC5-SMC6 complex localization factor protein 1 | chr5 | GO:0000781 | Not Cancer Driver | No | 70 | 0.0661625708884688 | 167 | 8 | 0.0075614366729678 | 0 |
| SLF2-201 | SLF2 | Q8IX21 | SMC5-SMC6 complex localization factor protein 2 | chr10 | GO:0000781 | Not Cancer Driver | No | 83 | 0.0707587382779198 | 726 | 58 | 0.0494458653026428 | 1 |
| SLX4-201 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | GO:0000781 | Not Cancer Driver | No | 201 | 0.1095965103598691 | 1586 | 175 | 0.0954198473282442 | 0 |
| SMC5-201 | SMC5 | Q8IY18 | Structural maintenance of chromosomes protein 5 | chr9 | GO:0000781 | Not Cancer Driver | No | 94 | 0.0853769300635785 | 381 | 35 | 0.0317892824704813 | 1 |
| SMC6-207 | SMC6 | Q96SB8 | Structural maintenance of chromosomes protein 6 | chr2 | GO:0000781 | Not Cancer Driver | No | 95 | 0.0870760769935838 | 459 | 43 | 0.0394133822181484 | 0 |
| SMCHD1-201 | SMCHD1 | A6NHR9 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | chr18 | GO:0000781 | Not Cancer Driver | No | 166 | 0.0827930174563591 | 345 | 34 | 0.0169576059850374 | 42 |
| SMG6-201 | SMG6 | Q86US8 | Telomerase-binding protein EST1A | chr17 | GO:0000781 | Not Cancer Driver | No | 121 | 0.0852713178294573 | 761 | 68 | 0.0479210711768851 | 0 |
| SP100-201 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | GO:0000781 | Not Cancer Driver | No | 76 | 0.08646188850967 | 683 | 61 | 0.0693970420932878 | 0 |
| SPDYA-201 | SPDYA | Q5MJ70 | Speedy protein A | chr2 | GO:0000781 | Not Cancer Driver | No | 25 | 0.0798722044728434 | 119 | 11 | 0.0351437699680511 | 0 |
| SPO11-203 | SPO11 | Q9Y5K1 | Meiotic recombination protein SPO11 | chr20 | GO:0000781 | Not Cancer Driver | No | 36 | 0.0909090909090909 | 26 | 2 | 0.005050505050505 | 0 |
| SSB-201 | SSB | P05455 | Lupus La protein | chr2 | GO:0000781 | Not Cancer Driver | No | 28 | 0.0686274509803921 | 181 | 16 | 0.0392156862745098 | 0 |
| STN1-201 | STN1 | Q9H668 | CST complex subunit STN1 | chr10 | GO:0000781 | Not Cancer Driver | No | 34 | 0.092391304347826 | 27 | 3 | 0.0081521739130434 | 2 |
| SUN1-203 | SUN1 | O94901 | SUN domain-containing protein 1 | chr7 | GO:0000781 | Not Cancer Driver | No | 81 | 0.1031847133757961 | 247 | 26 | 0.0331210191082802 | 0 |
| SUN2-218 | SUN2 | Q9UH99 | SUN domain-containing protein 2 | chr22 | GO:0000781 | Not Cancer Driver | No | 49 | 0.0683403068340306 | 214 | 13 | 0.0181311018131101 | 0 |
| TELO2-201 | TELO2 | Q9Y4R8 | Telomere length regulation protein TEL2 homolog | chr16 | GO:0000781 | Not Cancer Driver | No | 82 | 0.0979689366786141 | 155 | 15 | 0.017921146953405 | 5 |
| TEN1-201 | TEN1 | Q86WV5 | CST complex subunit TEN1 | chr17 | GO:0000781 | Not Cancer Driver | No | 4 | 0.032520325203252 | 8 | 2 | 0.016260162601626 | 0 |
| TEN1-CDK3-203 | TEN1 | Q86WV5 | CST complex subunit TEN1 | chr17 | GO:0000781 | Not Cancer Driver | No | 4 | 0.032520325203252 | 8 | 2 | 0.016260162601626 | 0 |
| TEP1-201 | TEP1 | Q99973 | Telomerase protein component 1 | chr14 | GO:0000781 | Not Cancer Driver | No | 251 | 0.0955462504758279 | 398 | 52 | 0.0197944423296536 | 0 |
| TERB1-202 | TERB1 | Q8NA31 | Telomere repeats-binding bouquet formation protein 1 | chr16 | GO:0000781 | Not Cancer Driver | No | 17 | 0.0233837689133425 | 201 | 8 | 0.0110041265474552 | 0 |
| TERB2-201 | TERB2 | Q8NHR7 | Telomere repeats-binding bouquet formation protein 2 | chr15 | GO:0000781 | Not Cancer Driver | No | 30 | 0.1363636363636363 | 36 | 5 | 0.0227272727272727 | 0 |
| TERF1-202 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | GO:0000781 | Not Cancer Driver | No | 51 | 0.1161731207289293 | 221 | 32 | 0.0728929384965831 | 0 |
| TERF2-201 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:0000781 | Not Cancer Driver | No | 26 | 0.047970479704797 | 361 | 15 | 0.0276752767527675 | 0 |
| TERF2IP-201 | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:0000781 | Not Cancer Driver | No | 20 | 0.050125313283208 | 312 | 12 | 0.0300751879699248 | 0 |
| TERT-201 | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:0000781 | Census | Yes | 86 | 0.0759717314487632 | 213 | 11 | 0.0097173144876325 | 32 |
| TFIP11-204 | TFIP11 | Q9UBB9 | Tuftelin-interacting protein 11 | chr22 | GO:0000781 | Not Cancer Driver | No | 58 | 0.069295101553166 | 333 | 26 | 0.031063321385902 | 0 |
| THOC1-201 | THOC1 | Q96FV9 | THO complex subunit 1 | chr18 | GO:0000781 | Not Cancer Driver | No | 38 | 0.0578386605783866 | 281 | 14 | 0.0213089802130898 | 0 |
| THOC2-201 | THOC2 | Q8NI27 | THO complex subunit 2 | chrX | GO:0000781 | Not Cancer Driver | No | 202 | 0.1268047708725674 | 549 | 78 | 0.0489642184557438 | 4 |
| THOC3-201 | THOC3 | Q96J01 | THO complex subunit 3 | chr5 | GO:0000781 | Not Cancer Driver | No | 17 | 0.0484330484330484 | 23 | 2 | 0.0056980056980056 | 0 |
| THOC5-216 | THOC5 | Q13769 | THO complex subunit 5 homolog | chr22 | GO:0000781 | Not Cancer Driver | No | 62 | 0.0907759882869692 | 174 | 16 | 0.0234260614934114 | 0 |
| THOC6-202 | THOC6 | Q86W42 | THO complex subunit 6 homolog | chr16 | GO:0000781 | Not Cancer Driver | No | 34 | 0.0997067448680351 | 16 | 3 | 0.0087976539589442 | 1 |
| THOC7-201 | THOC7 | Q6I9Y2 | THO complex subunit 7 homolog | chr3 | GO:0000781 | Not Cancer Driver | No | 17 | 0.0833333333333333 | 63 | 4 | 0.0196078431372549 | 0 |
| TINF2-201 | TINF2 | Q9BSI4 | TERF1-interacting nuclear factor 2 | chr14 | GO:0000781 | Not Cancer Driver | No | 29 | 0.0643015521064301 | 190 | 13 | 0.0288248337028824 | 3 |
| TNKS-201 | TNKS | O95271 | Poly [ADP-ribose] polymerase tankyrase-1 | chr8 | GO:0000781 | Not Cancer Driver | No | 102 | 0.0768651092690278 | 483 | 26 | 0.0195930670685757 | 0 |
| TNKS2-201 | TNKS2 | Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | chr10 | GO:0000781 | Not Cancer Driver | No | 99 | 0.0849056603773584 | 255 | 20 | 0.0171526586620926 | 0 |
| TOX4-203 | TOX4 | O94842 | TOX high mobility group box family member 4 | chr14 | GO:0000781 | Not Cancer Driver | No | 43 | 0.0692431561996779 | 563 | 38 | 0.0611916264090177 | 0 |
| TP53BP1-201 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | GO:0000781 | Not Cancer Driver | No | 159 | 0.0806288032454361 | 1638 | 131 | 0.0664300202839756 | 0 |
| TRIOBP-211 | TRIOBP | Q9H2D6 | TRIO and F-actin-binding protein | chr22 | GO:0000781 | Not Cancer Driver | No | 278 | 0.1175475687103594 | 2194 | 258 | 0.109090909090909 | 1 |
| UPF1-207 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0000781 | Not Cancer Driver | No | 114 | 0.1009743135518157 | 330 | 33 | 0.0292294065544729 | 0 |
| WDR82-201 | WDR82 | Q6UXN9 | WD repeat-containing protein 82 | chr3 | GO:0000781 | Not Cancer Driver | No | 23 | 0.0734824281150159 | 0 | 0 | 0.0 | 0 |
| WRAP53-202 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:0000781 | Not Cancer Driver | No | 46 | 0.083941605839416 | 234 | 21 | 0.0383211678832116 | 4 |
| WRN-201 | WRN | Q14191 | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | chr8 | GO:0000781 | Census, Compendium | Yes | 133 | 0.092877094972067 | 374 | 29 | 0.0202513966480446 | 2 |
| WRNIP1-204 | WRNIP1 | Q96S55 | ATPase WRNIP1 | chr6 | GO:0000781 | Not Cancer Driver | No | 32 | 0.0481203007518797 | 297 | 4 | 0.0060150375939849 | 0 |
| XRCC1-201 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0000781 | Not Cancer Driver | No | 58 | 0.0916271721958925 | 431 | 39 | 0.0616113744075829 | 1 |
| XRCC3-211 | XRCC3 | O43542 | DNA repair protein XRCC3 | chr14 | GO:0000781 | Not Cancer Driver | No | 21 | 0.0606936416184971 | 35 | 2 | 0.0057803468208092 | 1 |
| XRCC5-201 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0000781 | Not Cancer Driver | No | 53 | 0.0724043715846994 | 119 | 6 | 0.0081967213114754 | 0 |
| XRCC6-202 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0000781 | Not Cancer Driver | No | 49 | 0.0804597701149425 | 140 | 8 | 0.0131362889983579 | 0 |
| ZBTB10-204 | ZBTB10 | Q96DT7 | Zinc finger and BTB domain-containing protein 10 | chr8 | GO:0000781 | Not Cancer Driver | No | 39 | 0.044776119402985 | 531 | 24 | 0.0275545350172215 | 0 |
| ZBTB48-202 | ZBTB48 | P10074 | Telomere zinc finger-associated protein | chr1 | GO:0000781 | Not Cancer Driver | No | 40 | 0.0581395348837209 | 237 | 15 | 0.0218023255813953 | 0 |
| ZNF827-203 | ZNF827 | Q17R98 | Zinc finger protein 827 | chr4 | GO:0000781 | Not Cancer Driver | No | 117 | 0.1082331174838112 | 754 | 88 | 0.0814061054579093 | 0 |
| ZSCAN4-201 | ZSCAN4 | Q8NAM6 | Zinc finger and SCAN domain-containing protein 4 | chr19 | GO:0000781 | Not Cancer Driver | No | 85 | 0.1963048498845265 | 252 | 45 | 0.1039260969976905 | 0 |