Total number of protein in "GO:0001540" GO term: 89
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACHE-201 | ACHE | P22303 | Acetylcholinesterase | chr7 | GO:0001540 | Not Cancer Driver | No | 61 | 0.0993485342019544 | 64 | 6 | 0.009771986970684 | 0 |
| ADRB2-201 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | GO:0001540 | Not Cancer Driver | No | 36 | 0.0871670702179176 | 35 | 4 | 0.009685230024213 | 0 |
| AGER-206 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0001540 | Not Cancer Driver | No | 17 | 0.042079207920792 | 297 | 12 | 0.0297029702970297 | 0 |
| APBA1-201 | APBA1 | Q02410 | Amyloid-beta A4 precursor protein-binding family A member 1 | chr9 | GO:0001540 | Not Cancer Driver | No | 117 | 0.1397849462365591 | 558 | 78 | 0.0931899641577061 | 0 |
| APBA2-213 | APBA2 | Q99767 | Amyloid-beta A4 precursor protein-binding family A member 2 | chr15 | GO:0001540 | Not Cancer Driver | No | 151 | 0.2016021361815754 | 429 | 98 | 0.1308411214953271 | 0 |
| APBA3-201 | APBA3 | O96018 | Amyloid-beta A4 precursor protein-binding family A member 3 | chr19 | GO:0001540 | Not Cancer Driver | No | 35 | 0.0608695652173913 | 309 | 30 | 0.0521739130434782 | 0 |
| APBB1-220 | APBB1 | O00213 | Amyloid beta precursor protein binding family B member 1 | chr11 | GO:0001540 | Not Cancer Driver | No | 80 | 0.1126760563380281 | 400 | 43 | 0.0605633802816901 | 0 |
| APBB2-201 | APBB2 | Q92870 | Amyloid beta precursor protein binding family B member 2 | chr4 | GO:0001540 | Not Cancer Driver | No | 72 | 0.0949868073878627 | 420 | 39 | 0.0514511873350923 | 0 |
| APBB3-203 | APBB3 | O95704 | Amyloid-beta A4 precursor protein-binding family B member 3 | chr5 | GO:0001540 | Not Cancer Driver | No | 50 | 0.102880658436214 | 104 | 10 | 0.0205761316872428 | 0 |
| APOA1-201 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0001540 | Not Cancer Driver | No | 25 | 0.0936329588014981 | 131 | 9 | 0.0337078651685393 | 3 |
| APOE-201 | APOE | P02649 | Apolipoprotein E | chr19 | GO:0001540 | Not Cancer Driver | No | 20 | 0.0630914826498422 | 124 | 5 | 0.0157728706624605 | 10 |
| ATP1A3-214 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | GO:0001540 | Not Cancer Driver | No | 151 | 0.1490621915103652 | 116 | 21 | 0.0207305034550839 | 41 |
| BACE1-201 | BACE1 | P56817 | Beta-secretase 1 | chr11 | GO:0001540 | Not Cancer Driver | No | 34 | 0.0678642714570858 | 53 | 2 | 0.0039920159680638 | 0 |
| BCHE-201 | BCHE | P06276 | Cholinesterase | chr3 | GO:0001540 | Not Cancer Driver | No | 157 | 0.260797342192691 | 14 | 3 | 0.0049833887043189 | 37 |
| C1QA-201 | C1QA | P02745 | Complement C1q subcomponent subunit A | chr1 | GO:0001540 | Not Cancer Driver | No | 30 | 0.1224489795918367 | 125 | 11 | 0.0448979591836734 | 0 |
| CACNA1A-201 | CACNA1A | O00555 | Voltage-dependent P/Q-type calcium channel subunit alpha-1A | chr19 | GO:0001540 | Not Cancer Driver | No | 306 | 0.1221069433359936 | 1139 | 98 | 0.0391061452513966 | 46 |
| CACNA1B-204 | CACNA1B | Q00975 | Voltage-dependent N-type calcium channel subunit alpha-1B | chr9 | GO:0001540 | Not Cancer Driver | No | 303 | 0.1295425395468148 | 918 | 84 | 0.0359127832407011 | 0 |
| CALCR-204 | CALCR | P30988 | Calcitonin receptor | chr7 | GO:0001540 | Not Cancer Driver | No | 124 | 0.2616033755274262 | 22 | 6 | 0.0126582278481012 | 0 |
| CD36-214 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0001540 | Not Cancer Driver | No | 48 | 0.1016949152542373 | 12 | 3 | 0.0063559322033898 | 3 |
| CD74-201 | CD74 | P04233 | HLA class II histocompatibility antigen gamma chain | chr5 | GO:0001540 | Census | Yes | 24 | 0.081081081081081 | 186 | 15 | 0.0506756756756756 | 0 |
| CHRNA7-201 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0001540 | Not Cancer Driver | No | 50 | 0.099601593625498 | 18 | 3 | 0.0059760956175298 | 0 |
| CLSTN1-202 | CLSTN1 | O94985 | Calsyntenin-1 | chr1 | GO:0001540 | Not Cancer Driver | No | 81 | 0.0825688073394495 | 271 | 14 | 0.0142711518858307 | 0 |
| CLSTN2-201 | CLSTN2 | Q9H4D0 | Calsyntenin-2 | chr3 | GO:0001540 | Not Cancer Driver | No | 197 | 0.206282722513089 | 179 | 39 | 0.0408376963350785 | 0 |
| CLSTN3-201 | CLSTN3 | Q9BQT9 | Calsyntenin-3 | chr12 | GO:0001540 | Not Cancer Driver | No | 106 | 0.1108786610878661 | 211 | 18 | 0.0188284518828451 | 0 |
| CLU-201 | CLU | P10909 | Clusterin | chr8 | GO:0001540 | Not Cancer Driver | No | 43 | 0.0957683741648107 | 157 | 18 | 0.0400890868596882 | 0 |
| COL25A1-203 | COL25A1 | Q9BXS0 | Collagen alpha-1(XXV) chain | chr4 | GO:0001540 | Not Cancer Driver | No | 88 | 0.1345565749235474 | 622 | 88 | 0.1345565749235474 | 1 |
| CRYAB-217 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | GO:0001540 | Not Cancer Driver | No | 17 | 0.0971428571428571 | 59 | 7 | 0.04 | 5 |
| CST3-201 | CST3 | P01034 | Cystatin-C | chr20 | GO:0001540 | Not Cancer Driver | No | 7 | 0.047945205479452 | 31 | 1 | 0.0068493150684931 | 2 |
| DLGAP3-202 | DLGAP3 | O95886 | Disks large-associated protein 3 | chr1 | GO:0001540 | Not Cancer Driver | No | 135 | 0.1378958120531154 | 812 | 116 | 0.118488253319714 | 0 |
| ENST00000644613 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | GO:0001540 | Not Cancer Driver | No | 151 | 0.1495049504950495 | 115 | 21 | 0.0207920792079207 | 39 |
| EPHA4-201 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0001540 | Not Cancer Driver | No | 132 | 0.1338742393509127 | 141 | 16 | 0.0162271805273833 | 0 |
| EPHB2-204 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0001540 | Not Cancer Driver | No | 149 | 0.1412322274881516 | 120 | 11 | 0.0104265402843601 | 7 |
| FBXO2-201 | FBXO2 | Q9UK22 | F-box only protein 2 | chr1 | GO:0001540 | Not Cancer Driver | No | 16 | 0.054054054054054 | 76 | 0 | 0.0 | 0 |
| FCGR2B-202 | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0001540 | Census | Yes | 38 | 0.1225806451612903 | 100 | 23 | 0.0741935483870967 | 0 |
| FPR2-201 | FPR2 | P25090 | N-formyl peptide receptor 2 | chr19 | GO:0001540 | Not Cancer Driver | No | 92 | 0.2621082621082621 | 26 | 7 | 0.0199430199430199 | 0 |
| FZD4-201 | FZD4 | Q9ULV1 | Frizzled-4 | chr11 | GO:0001540 | Not Cancer Driver | No | 40 | 0.074487895716946 | 33 | 5 | 0.0093109869646182 | 17 |
| FZD5-201 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0001540 | Not Cancer Driver | No | 39 | 0.0666666666666666 | 58 | 3 | 0.0051282051282051 | 0 |
| FZD6-201 | FZD6 | O60353 | Frizzled-6 | chr8 | GO:0001540 | Not Cancer Driver | No | 60 | 0.0849858356940509 | 173 | 14 | 0.0198300283286118 | 1 |
| GPRASP2-202 | GPRASP2 | Q96D09 | G-protein coupled receptor-associated sorting protein 2 | chrX | GO:0001540 | Not Cancer Driver | No | 100 | 0.1193317422434367 | 510 | 62 | 0.0739856801909307 | 1 |
| GRIA1-201 | GRIA1 | P42261 | Glutamate receptor 1 | chr5 | GO:0001540 | Not Cancer Driver | No | 252 | 0.2781456953642384 | 104 | 37 | 0.0408388520971302 | 3 |
| GRIA2-201 | GRIA2 | P42262 | Glutamate receptor 2 | chr4 | GO:0001540 | Not Cancer Driver | No | 217 | 0.2457531143827859 | 50 | 15 | 0.0169875424688561 | 14 |
| GRIA3-208 | GRIA3 | P42263 | Glutamate receptor 3 | chrX | GO:0001540 | Not Cancer Driver | No | 168 | 0.1879194630872483 | 56 | 12 | 0.0134228187919463 | 4 |
| GRIA4-201 | GRIA4 | P48058 | Glutamate receptor 4 | chr11 | GO:0001540 | Not Cancer Driver | No | 169 | 0.1873614190687361 | 63 | 17 | 0.0188470066518847 | 4 |
| GRIN1-208 | GRIN1 | Q05586 | Glutamate receptor ionotropic, NMDA 1 | chr9 | GO:0001540 | Not Cancer Driver | No | 71 | 0.0756929637526652 | 190 | 8 | 0.0085287846481876 | 12 |
| GRIN2A-201 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0001540 | Census, Compendium | Yes | 439 | 0.2998633879781421 | 507 | 172 | 0.1174863387978142 | 32 |
| GRIN2B-201 | GRIN2B | Q13224 | Glutamate receptor ionotropic, NMDA 2B | chr12 | GO:0001540 | Not Cancer Driver | No | 331 | 0.2230458221024258 | 428 | 116 | 0.0781671159029649 | 12 |
| GSAP-201 | GSAP | A4D1B5 | Gamma-secretase-activating protein | chr7 | GO:0001540 | Not Cancer Driver | No | 60 | 0.0702576112412178 | 13 | 0 | 0.0 | 0 |
| HSPG2-203 | HSPG2 | P98160 | Basement membrane-specific heparan sulfate proteoglycan core protein | chr1 | GO:0001540 | Compendium | Yes | 414 | 0.0942837622409474 | 1724 | 160 | 0.0364381689820086 | 1 |
| IAPP-201 | IAPP | P10997 | Islet amyloid polypeptide | chr12 | GO:0001540 | Not Cancer Driver | No | 19 | 0.2134831460674157 | 10 | 4 | 0.0449438202247191 | 0 |
| INSR-201 | INSR | P06213 | Insulin receptor | chr19 | GO:0001540 | Not Cancer Driver | No | 139 | 0.1005788712011577 | 282 | 37 | 0.0267727930535455 | 63 |
| ITGA2-201 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0001540 | Not Cancer Driver | No | 116 | 0.0982218458933107 | 26 | 0 | 0.0 | 0 |
| ITGAM-201 | ITGAM | P11215 | Integrin alpha-M | chr16 | GO:0001540 | Not Cancer Driver | No | 142 | 0.1232638888888889 | 133 | 9 | 0.0078125 | 0 |
| ITGB2-225 | ITGB2 | P05107 | Integrin beta-2 | chr21 | GO:0001540 | Not Cancer Driver | No | 113 | 0.1469440832249675 | 59 | 7 | 0.0091027308192457 | 15 |
| ITM2A-201 | ITM2A | O43736 | Integral membrane protein 2A | chrX | GO:0001540 | Not Cancer Driver | No | 63 | 0.2395437262357414 | 26 | 9 | 0.0342205323193916 | 0 |
| ITM2B-204 | ITM2B | Q9Y287 | Integral membrane protein 2B | chr13 | GO:0001540 | Not Cancer Driver | No | 15 | 0.056390977443609 | 12 | 0 | 0.0 | 1 |
| ITM2C-202 | ITM2C | Q9NQX7 | Integral membrane protein 2C | chr2 | GO:0001540 | Not Cancer Driver | No | 22 | 0.0823970037453183 | 33 | 3 | 0.0112359550561797 | 0 |
| KIR3DL1-203 | KIR3DL1 | P43629 | Killer cell immunoglobulin-like receptor 3DL1 | chr19 | GO:0001540 | Not Cancer Driver | No | 97 | 0.2184684684684684 | 184 | 39 | 0.0878378378378378 | 0 |
| LDLR-208 | LDLR | P01130 | Low-density lipoprotein receptor | chr19 | GO:0001540 | Not Cancer Driver | No | 94 | 0.1093023255813953 | 63 | 3 | 0.0034883720930232 | 87 |
| LDLRAD3-201 | LDLRAD3 | Q86YD5 | Low-density lipoprotein receptor class A domain-containing protein 3 | chr11 | GO:0001540 | Not Cancer Driver | No | 30 | 0.0869565217391304 | 123 | 10 | 0.0289855072463768 | 0 |
| LDLRAP1-201 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0001540 | Not Cancer Driver | No | 29 | 0.0941558441558441 | 121 | 9 | 0.0292207792207792 | 2 |
| LILRB1-201 | LILRB1 | Q8NHL6 | Leukocyte immunoglobulin-like receptor subfamily B member 1 | chr19 | GO:0001540 | Not Cancer Driver | No | 170 | 0.2607361963190184 | 325 | 86 | 0.1319018404907975 | 0 |
| LILRB2-201 | LILRB2 | Q8N423 | Leukocyte immunoglobulin-like receptor subfamily B member 2 | chr19 | GO:0001540 | Not Cancer Driver | No | 120 | 0.2010050251256281 | 235 | 41 | 0.0686767169179229 | 0 |
| LILRB3-206 | LILRB3 | O75022 | Leukocyte immunoglobulin-like receptor subfamily B member 3 | chr19 | GO:0001540 | Not Cancer Driver | No | 54 | 0.0855784469096671 | 296 | 39 | 0.0618066561014263 | 0 |
| LRP1-201 | LRP1 | Q07954 | Prolow-density lipoprotein receptor-related protein 1 | chr12 | GO:0001540 | Not Cancer Driver | No | 512 | 0.1126760563380281 | 319 | 38 | 0.008362676056338 | 1 |
| LRP8-201 | LRP8 | Q14114 | Low-density lipoprotein receptor-related protein 8 | chr1 | GO:0001540 | Not Cancer Driver | No | 70 | 0.0726895119418483 | 190 | 17 | 0.0176531671858774 | 0 |
| LRPAP1-205 | LRPAP1 | P30533 | Alpha-2-macroglobulin receptor-associated protein | chr4 | GO:0001540 | Not Cancer Driver | No | 29 | 0.0812324929971988 | 189 | 16 | 0.0448179271708683 | 0 |
| MAPK8IP2-202 | MAPK8IP2 | Q13387 | C-Jun-amino-terminal kinase-interacting protein 2 | chr22 | GO:0001540 | Not Cancer Driver | No | 42 | 0.0509708737864077 | 574 | 25 | 0.0303398058252427 | 0 |
| MARCO-201 | MARCO | Q9UEW3 | Macrophage receptor MARCO | chr2 | GO:0001540 | Not Cancer Driver | No | 82 | 0.1576923076923077 | 323 | 59 | 0.1134615384615384 | 0 |
| MSR1-201 | MSR1 | P21757 | Macrophage scavenger receptor types I and II | chr8 | GO:0001540 | Not Cancer Driver | No | 136 | 0.3015521064301552 | 244 | 90 | 0.1995565410199556 | 0 |
| NGFR-201 | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | GO:0001540 | Not Cancer Driver | No | 46 | 0.1077283372365339 | 174 | 23 | 0.0538641686182669 | 0 |
| NLGN1-203 | NLGN1 | Q8N2Q7 | Neuroligin-1 | chr3 | GO:0001540 | Not Cancer Driver | No | 174 | 0.20162224797219 | 250 | 52 | 0.0602549246813441 | 4 |
| PFDN1-201 | PFDN1 | O60925 | Prefoldin subunit 1 | chr5 | GO:0001540 | Not Cancer Driver | No | 6 | 0.0491803278688524 | 42 | 3 | 0.0245901639344262 | 0 |
| PFDN2-201 | PFDN2 | Q9UHV9 | Prefoldin subunit 2 | chr1 | GO:0001540 | Not Cancer Driver | No | 16 | 0.1038961038961039 | 111 | 10 | 0.0649350649350649 | 0 |
| PFDN4-201 | PFDN4 | Q9NQP4 | Prefoldin subunit 4 | chr20 | GO:0001540 | Not Cancer Driver | No | 13 | 0.0970149253731343 | 41 | 3 | 0.0223880597014925 | 0 |
| PFDN5-202 | PFDN5 | Q99471 | Prefoldin subunit 5 | chr12 | GO:0001540 | Not Cancer Driver | No | 16 | 0.1038961038961039 | 3 | 0 | 0.0 | 0 |
| PFDN6-201 | PFDN6 | O15212 | Prefoldin subunit 6 | chr6 | GO:0001540 | Not Cancer Driver | No | 12 | 0.0930232558139534 | 57 | 8 | 0.0620155038759689 | 0 |
| PGRMC1-201 | PGRMC1 | O00264 | Membrane-associated progesterone receptor component 1 | chrX | GO:0001540 | Not Cancer Driver | No | 23 | 0.1179487179487179 | 74 | 11 | 0.0564102564102564 | 0 |
| PICALM-202 | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0001540 | Census | Yes | 64 | 0.0981595092024539 | 320 | 31 | 0.0475460122699386 | 0 |
| PRNP-201 | PRNP | P04156 | Major prion protein | chr20 | GO:0001540 | Not Cancer Driver | No | 28 | 0.1106719367588932 | 117 | 8 | 0.0316205533596837 | 19 |
| RAMP3-201 | RAMP3 | O60896 | Receptor activity-modifying protein 3 | chr7 | GO:0001540 | Not Cancer Driver | No | 18 | 0.1216216216216216 | 0 | 0 | 0.0 | 0 |
| SCARB1-203 | SCARB1 | Q8WTV0 | Scavenger receptor class B member 1 | chr12 | GO:0001540 | Not Cancer Driver | No | 33 | 0.0597826086956521 | 6 | 0 | 0.0 | 0 |
| SORL1-201 | SORL1 | Q92673 | Sortilin-related receptor | chr11 | GO:0001540 | Not Cancer Driver | No | 298 | 0.1345980126467931 | 87 | 8 | 0.003613369467028 | 0 |
| TGFB2-202 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0001540 | Not Cancer Driver | No | 44 | 0.1062801932367149 | 47 | 5 | 0.0120772946859903 | 4 |
| TLR2-203 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0001540 | Not Cancer Driver | No | 84 | 0.1071428571428571 | 0 | 0 | 0.0 | 0 |
| TLR4-201 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0001540 | Not Cancer Driver | No | 253 | 0.301549463647199 | 0 | 0 | 0.0 | 0 |
| TLR6-202 | TLR6 | Q9Y2C9 | Toll-like receptor 6 | chr4 | GO:0001540 | Not Cancer Driver | No | 69 | 0.0866834170854271 | 1 | 0 | 0.0 | 0 |
| TM2D1-211 | TM2D1 | Q9BX74 | TM2 domain-containing protein 1 | chr1 | GO:0001540 | Not Cancer Driver | No | 22 | 0.1062801932367149 | 11 | 6 | 0.0289855072463768 | 0 |
| TREM2-202 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0001540 | Not Cancer Driver | No | 31 | 0.1347826086956521 | 27 | 2 | 0.008695652173913 | 1 |
| VBP1-201 | VBP1 | P61758 | Prefoldin subunit 3 | chrX | GO:0001540 | Not Cancer Driver | No | 16 | 0.0812182741116751 | 47 | 5 | 0.0253807106598984 | 0 |