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Total number of protein in "GO:0001649" GO term:  125

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAR-202 ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0001649 Not Cancer Driver No 102 0.0831973898858075 677 56 0.0456769983686786 12
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0001649 Census, Compendium Yes 99 0.20625 158 19 0.0395833333333333 4
ALPL-204 ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0001649 Not Cancer Driver No 56 0.1068702290076335 186 28 0.0534351145038167 96
ALYREF-202 ALYREF Q86V81 THO complex subunit 4 chr17 GO:0001649 Not Cancer Driver No 30 0.1136363636363636 230 26 0.0984848484848484 0
AMELX-203 AMELX Q99217 Amelogenin, X isoform chrX GO:0001649 Not Cancer Driver No 9 0.0471204188481675 127 0 0.0 3
ASF1A-201 ASF1A Q9Y294 Histone chaperone ASF1A chr6 GO:0001649 Not Cancer Driver No 11 0.0539215686274509 69 2 0.0098039215686274 0
ATP5F1B-201 ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0001649 Not Cancer Driver No 46 0.0869565217391304 85 7 0.0132325141776937 1
AXIN2-201 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0001649 Census, Compendium Yes 82 0.0972716488730723 551 51 0.0604982206405693 0
BCAP29-201 BCAP29 Q9UHQ4 B-cell receptor-associated protein 29 chr7 GO:0001649 Not Cancer Driver No 21 0.0871369294605809 96 10 0.0414937759336099 0
BGLAP-201 BGLAP P02818 Osteocalcin chr1 GO:0001649 Not Cancer Driver No 6 0.06 21 0 0.0 0
BMP2-201 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0001649 Not Cancer Driver No 54 0.1363636363636363 140 22 0.0555555555555555 0
BMP3-201 BMP3 P12645 Bone morphogenetic protein 3 chr4 GO:0001649 Not Cancer Driver No 88 0.1864406779661017 148 37 0.0783898305084745 0
BMP4-201 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0001649 Not Cancer Driver No 69 0.1691176470588235 142 20 0.0490196078431372 5
BMP6-201 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0001649 Not Cancer Driver No 79 0.1539961013645224 228 41 0.0799220272904483 6
BMPR1A-201 BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0001649 Census, Compendium Yes 37 0.0695488721804511 21 0 0.0 8
BMPR1B-208 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0001649 Not Cancer Driver No 55 0.1095617529880478 64 4 0.0079681274900398 4
BMPR2-202 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0001649 Compendium Yes 100 0.0963391136801541 601 49 0.0472061657032755 17
CAT-201 CAT P04040 Catalase chr11 GO:0001649 Not Cancer Driver No 56 0.1062618595825427 178 11 0.0208728652751423 0
CBFB-201 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0001649 Census, Compendium Yes 29 0.1593406593406593 95 9 0.0494505494505494 0
CCDC47-201 CCDC47 Q96A33 PAT complex subunit CCDC47 chr17 GO:0001649 Not Cancer Driver No 36 0.0745341614906832 266 16 0.0331262939958592 0
CCL3-204 CCL3 P10147 C-C motif chemokine 3 chr17 GO:0001649 Not Cancer Driver No 13 0.1413043478260869 0 0 0.0 0
CCN1-201 CCN1 O00622 CCN family member 1 chr1 GO:0001649 Not Cancer Driver No 29 0.0761154855643044 12 0 0.0 0
CCN4-202 CCN4 O95388 CCN family member 4 chr8 GO:0001649 Not Cancer Driver No 84 0.2288828337874659 20 7 0.0190735694822888 0
CLTC-201 CLTC Q00610 Clathrin heavy chain 1 chr17 GO:0001649 Census, Compendium Yes 132 0.0788059701492537 71 5 0.0029850746268656 1
COL1A1-201 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0001649 Census, Compendium Yes 36 0.0245901639344262 1213 10 0.0068306010928961 140
COL6A1-201 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 GO:0001649 Not Cancer Driver No 68 0.0661478599221789 436 23 0.0223735408560311 12
CREB3L1-206 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0001649 Census Yes 54 0.1040462427745664 373 39 0.0751445086705202 0
CTHRC1-201 CTHRC1 Q96CG8 Collagen triple helix repeat-containing protein 1 chr8 GO:0001649 Not Cancer Driver No 19 0.0781893004115226 62 6 0.0246913580246913 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 GO:0001649 Census, Compendium Yes 363 0.4647887323943662 288 291 0.3725992317541613 11
CYP24A1-201 CYP24A1 Q07973 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial chr20 GO:0001649 Not Cancer Driver No 54 0.1050583657587548 77 4 0.0077821011673151 4
DDX21-201 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0001649 Not Cancer Driver No 54 0.0689655172413793 343 24 0.0306513409961685 0
DHH-201 DHH O43323 Desert hedgehog protein chr12 GO:0001649 Not Cancer Driver No 28 0.0707070707070707 57 5 0.0126262626262626 1
DHX9-201 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0001649 Compendium Yes 125 0.0984251968503937 332 30 0.0236220472440944 0
DLX5-203 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:0001649 Not Cancer Driver No 64 0.2214532871972318 223 54 0.1868512110726643 1
DNAJC13-201 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 GO:0001649 Not Cancer Driver No 190 0.084707980383415 142 13 0.0057958091841284 0
ENST00000682083 SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0001649 Not Cancer Driver No 34 0.0604982206405693 225 7 0.0124555160142348 0
ENST00000695929 TMT1A Q9H8H3 N6-adenosine-methyltransferase TMT1A chr12 GO:0001649 Not Cancer Driver No 20 0.0823045267489712 0 0 0.0 0
EPHA2-201 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0001649 Compendium Yes 147 0.1506147540983606 188 33 0.033811475409836 3
FASN-201 FASN P49327 Fatty acid synthase chr17 GO:0001649 Not Cancer Driver No 241 0.0959776981282357 310 33 0.013142174432497 0
FBL-201 FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 GO:0001649 Not Cancer Driver No 21 0.0654205607476635 145 3 0.0093457943925233 0
FGF2-201 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0001649 Not Cancer Driver No 17 0.0590277777777777 183 5 0.0173611111111111 0
FGF9-201 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0001649 Not Cancer Driver No 33 0.1586538461538461 43 8 0.0384615384615384 1
FHL2-211 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 GO:0001649 Not Cancer Driver No 17 0.060931899641577 0 0 0.0 0
FIGNL1-206 FIGNL1 Q6PIW4 Fidgetin-like protein 1 chr7 GO:0001649 Not Cancer Driver No 53 0.0786350148367952 226 15 0.0222551928783382 0
FOSL2-201 FOSL2 P15408 Fos-related antigen 2 chr2 GO:0001649 Not Cancer Driver No 39 0.1196319018404908 323 39 0.1196319018404908 0
GABBR1-204 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0001649 Not Cancer Driver No 117 0.1217481789802289 142 16 0.0166493236212278 0
GDF10-201 GDF10 P55107 Growth/differentiation factor 10 chr10 GO:0001649 Not Cancer Driver No 81 0.1694560669456067 254 54 0.1129707112970711 0
GDF2-201 GDF2 Q9UK05 Growth/differentiation factor 2 chr10 GO:0001649 Not Cancer Driver No 106 0.247086247086247 130 40 0.0932400932400932 3
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0001649 Not Cancer Driver No 62 0.1623036649214659 111 20 0.0523560209424083 43
GLI1-201 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0001649 Census, Compendium Yes 156 0.1410488245931284 1018 138 0.1247739602169981 0
GLI3-201 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0001649 Not Cancer Driver No 308 0.1949367088607595 1362 270 0.170886075949367 7
GTPBP4-202 GTPBP4 Q9BZE4 GTP-binding protein 4 chr10 GO:0001649 Not Cancer Driver No 54 0.085173501577287 233 20 0.0315457413249211 0
HAND2-201 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0001649 Not Cancer Driver No 39 0.1797235023041474 124 24 0.1105990783410138 0
HIRA-201 HIRA P54198 Protein HIRA chr22 GO:0001649 Not Cancer Driver No 104 0.1022615535889872 289 30 0.0294985250737463 0
HNRNPC-202 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:0001649 Not Cancer Driver No 27 0.088235294117647 228 22 0.0718954248366013 0
HNRNPU-226 HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0001649 Not Cancer Driver No 57 0.069090909090909 505 36 0.0436363636363636 0
HSD17B4-211 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 GO:0001649 Not Cancer Driver No 72 0.0978260869565217 83 11 0.014945652173913 4
HSPE1-201 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 GO:0001649 Not Cancer Driver No 6 0.0588235294117647 3 0 0.0 0
IARS1-203 IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 GO:0001649 Not Cancer Driver No 99 0.0784469096671949 28 2 0.0015847860538827 4
IBSP-201 IBSP P21815 Bone sialoprotein 2 chr4 GO:0001649 Not Cancer Driver No 54 0.1703470031545741 278 47 0.1482649842271293 0
ID4-201 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0001649 Not Cancer Driver No 5 0.031055900621118 72 1 0.0062111801242236 0
IFT80-201 IFT80 Q9P2H3 Intraflagellar transport protein 80 homolog chr3 GO:0001649 Not Cancer Driver No 84 0.1081081081081081 21 1 0.0012870012870012 2
IGF2-205 IGF2 P01344 Insulin-like growth factor II chr11 GO:0001649 Not Cancer Driver No 32 0.1777777777777777 44 10 0.0555555555555555 0
IGFBP3-209 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 GO:0001649 Not Cancer Driver No 35 0.120274914089347 104 20 0.0687285223367697 0
IGFBP5-201 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0001649 Not Cancer Driver No 23 0.0845588235294117 112 18 0.0661764705882353 0
IHH-201 IHH Q14623 Indian hedgehog protein chr2 GO:0001649 Not Cancer Driver No 50 0.121654501216545 111 14 0.0340632603406326 5
ITGA11-201 ITGA11 Q9UKX5 Integrin alpha-11 chr15 GO:0001649 Not Cancer Driver No 126 0.106060606060606 104 9 0.0075757575757575 0
JUNB-201 JUNB P17275 Transcription factor JunB chr19 GO:0001649 Not Cancer Driver No 20 0.0576368876080691 305 18 0.0518731988472622 0
LEF1-201 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0001649 Census Yes 51 0.1278195488721804 372 47 0.1177944862155388 0
LGR4-201 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0001649 Not Cancer Driver No 73 0.0767613038906414 16 2 0.0021030494216614 0
LOX-201 LOX P28300 Protein-lysine 6-oxidase chr5 GO:0001649 Compendium Yes 31 0.0743405275779376 172 8 0.0191846522781774 4
LRRC17-202 LRRC17 Q8N6Y2 Leucine-rich repeat-containing protein 17 chr7 GO:0001649 Not Cancer Driver No 43 0.0975056689342403 90 7 0.0158730158730158 0
MAP2K6-206 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0001649 Not Cancer Driver No 28 0.0838323353293413 55 6 0.0179640718562874 0
MAPK11-201 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0001649 Not Cancer Driver No 22 0.0604395604395604 64 2 0.0054945054945054 0
MAPK14-201 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0001649 Not Cancer Driver No 22 0.0611111111111111 25 0 0.0 0
MEF2C-209 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0001649 Not Cancer Driver No 54 0.1141649048625792 408 51 0.1078224101479915 2
MEF2D-201 MEF2D Q14814 Myocyte-specific enhancer factor 2D chr1 GO:0001649 Not Cancer Driver No 46 0.0882917466410748 457 43 0.0825335892514395 0
METTL7A-201 TMT1A Q9H8H3 N6-adenosine-methyltransferase TMT1A chr12 GO:0001649 Not Cancer Driver No 22 0.0901639344262295 0 0 0.0 0
MRC2-201 MRC2 Q9UBG0 C-type mannose receptor 2 chr17 GO:0001649 Not Cancer Driver No 141 0.0953346855983772 257 26 0.0175794455713319 0
MSX2-201 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0001649 Not Cancer Driver No 21 0.0786516853932584 170 10 0.0374531835205992 3
MYBBP1A-201 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0001649 Not Cancer Driver No 100 0.0753012048192771 468 37 0.0278614457831325 0
MYOC-201 MYOC Q99972 Myocilin chr1 GO:0001649 Not Cancer Driver No 76 0.1507936507936507 197 36 0.0714285714285714 49
NF1-202 NF1 P21359 Neurofibromin chr17 GO:0001649 Census, Compendium Yes 285 0.1003874603733709 406 36 0.0126805213103205 75
NOG-201 NOG Q13253 Noggin chr17 GO:0001649 Not Cancer Driver No 15 0.0646551724137931 87 5 0.021551724137931 17
NR1I3-204 NR1I3 Q14994 Nuclear receptor subfamily 1 group I member 3 chr1 GO:0001649 Not Cancer Driver No 46 0.1306818181818181 23 2 0.0056818181818181 0
PENK-202 PENK P01210 Proenkephalin-A chr8 GO:0001649 Not Cancer Driver No 92 0.3445692883895131 143 55 0.2059925093632958 0
PHB1-201 PHB1 P35232 Prohibitin 1 chr17 GO:0001649 Not Cancer Driver No 21 0.0772058823529411 4 1 0.0036764705882352 0
PSMC2-201 PSMC2 P35998 26S proteasome regulatory subunit 7 chr7 GO:0001649 Not Cancer Driver No 53 0.1224018475750577 120 14 0.0323325635103926 0
RBMX-201 RBMX P38159 RNA-binding motif protein, X chromosome chrX GO:0001649 Not Cancer Driver No 41 0.1048593350383631 381 41 0.1048593350383631 0
RDH14-201 RDH14 Q9HBH5 Retinol dehydrogenase 14 chr2 GO:0001649 Not Cancer Driver No 13 0.0386904761904761 21 0 0.0 0
RPS15-209 RPS15 P62841 Small ribosomal subunit protein uS19 chr19 GO:0001649 Not Cancer Driver No 10 0.0689655172413793 59 6 0.0413793103448275 0
RRAS2-201 RRAS2 P62070 Ras-related protein R-Ras2 chr11 GO:0001649 Compendium Yes 27 0.1323529411764706 37 1 0.0049019607843137 3
RRBP1-204 RRBP1 Q9P2E9 Ribosome-binding protein 1 chr20 GO:0001649 Not Cancer Driver No 97 0.0687943262411347 1307 89 0.0631205673758865 0
RSL1D1-204 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 GO:0001649 Not Cancer Driver No 34 0.0693877551020408 276 18 0.036734693877551 0
RSPO2-201 RSPO2 Q6UXX9 R-spondin-2 chr8 GO:0001649 Census Yes 67 0.2757201646090535 41 5 0.0205761316872428 1
RUNX2-212 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0001649 Not Cancer Driver No 50 0.0959692898272552 447 44 0.0844529750479846 30
SEMA7A-201 SEMA7A O75326 Semaphorin-7A chr15 GO:0001649 Not Cancer Driver No 64 0.0960960960960961 150 19 0.0285285285285285 1
SFRP1-201 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0001649 Not Cancer Driver No 31 0.0987261146496815 39 4 0.0127388535031847 0
SHOX2-202 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0001649 Not Cancer Driver No 45 0.1359516616314199 200 29 0.0876132930513595 0
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0001649 Not Cancer Driver No 34 0.085 163 10 0.025 0
SMAD4-201 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0001649 Census, Compendium Yes 172 0.3115942028985507 195 16 0.0289855072463768 6
SMAD5-211 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0001649 Not Cancer Driver No 25 0.053763440860215 172 6 0.0129032258064516 0
SMO-201 SMO Q99835 Protein smoothened chr7 GO:0001649 Census, Compendium Yes 88 0.1118170266836086 242 20 0.025412960609911 1
SNAI1-201 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0001649 Not Cancer Driver No 41 0.1553030303030303 98 8 0.0303030303030303 0
SNAI2-201 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0001649 Not Cancer Driver No 43 0.1604477611940298 52 8 0.0298507462686567 0
SND1-201 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 GO:0001649 Census Yes 97 0.1065934065934065 258 33 0.0362637362637362 0
SNRNP200-201 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 GO:0001649 Not Cancer Driver No 168 0.0786516853932584 271 25 0.0117041198501872 10
SOX2-201 SOX2 P48431 Transcription factor SOX-2 chr3 GO:0001649 Census Yes 32 0.1009463722397476 312 32 0.1009463722397476 0
SOX8-201 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0001649 Not Cancer Driver No 38 0.085201793721973 403 35 0.0784753363228699 0
SP7-202 SP7 Q8TDD2 Transcription factor Sp7 chr12 GO:0001649 Not Cancer Driver No 46 0.1067285382830626 332 32 0.074245939675174 0
SPP1-203 SPP1 P10451 Osteopontin chr4 GO:0001649 Not Cancer Driver No 41 0.1305732484076433 302 40 0.1273885350318471 0
SYNCRIP-202 SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0001649 Not Cancer Driver No 34 0.0545746388443017 285 7 0.0112359550561797 0
TMEM119-201 TMEM119 Q4V9L6 Transmembrane protein 119 chr12 GO:0001649 Not Cancer Driver No 44 0.1554770318021201 195 35 0.1236749116607773 0
TNC-202 TNC P24821 Tenascin chr9 GO:0001649 Census, Compendium Yes 241 0.1094956837800999 575 78 0.0354384370740572 2
TP53INP2-202 TP53INP2 Q8IXH6 Tumor protein p53-inducible nuclear protein 2 chr20 GO:0001649 Not Cancer Driver No 17 0.0772727272727272 198 15 0.0681818181818181 0
TPM4-218 TPM4 P67936 Tropomyosin alpha-4 chain chr19 GO:0001649 Census Yes 21 0.0846774193548387 216 21 0.0846774193548387 0
TWIST1-201 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0001649 Not Cancer Driver No 21 0.1039603960396039 132 9 0.0445544554455445 6
UCMA-201 UCMA Q8WVF2 Unique cartilage matrix-associated protein chr10 GO:0001649 Not Cancer Driver No 22 0.1594202898550724 96 14 0.1014492753623188 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0001649 Not Cancer Driver No 77 0.096977329974811 141 19 0.0239294710327455 0
VCAN-201 VCAN P13611 Versican core protein chr5 GO:0001649 Not Cancer Driver No 487 0.1434040047114252 2654 365 0.1074793875147232 0
WNT10B-201 WNT10B O00744 Protein Wnt-10b chr12 GO:0001649 Not Cancer Driver No 45 0.1156812339331619 84 14 0.0359897172236503 2
WNT11-201 WNT11 O96014 Protein Wnt-11 chr11 GO:0001649 Not Cancer Driver No 37 0.1045197740112994 59 3 0.0084745762711864 0
WNT3A-201 WNT3A P56704 Protein Wnt-3a chr1 GO:0001649 Not Cancer Driver No 60 0.1704545454545454 37 2 0.0056818181818181 0
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 GO:0001649 Not Cancer Driver No 50 0.1207729468599033 109 7 0.0169082125603864 3
WWTR1-201 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0001649 Census Yes 29 0.0725 389 29 0.0725 0