Total number of protein in "GO:0001726" GO term: 96
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0001726 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| ACAP2-201 | ACAP2 | Q15057 | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 | chr3 | GO:0001726 | Not Cancer Driver | No | 66 | 0.0848329048843187 | 287 | 26 | 0.0334190231362467 | 0 |
| ACTN1-201 | ACTN1 | P12814 | Alpha-actinin-1 | chr14 | GO:0001726 | Not Cancer Driver | No | 84 | 0.0941704035874439 | 195 | 25 | 0.0280269058295964 | 6 |
| AIF1-203 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | GO:0001726 | Not Cancer Driver | No | 12 | 0.0816326530612244 | 61 | 5 | 0.0340136054421768 | 0 |
| ALS2-201 | ALS2 | Q96Q42 | Alsin | chr2 | GO:0001726 | Not Cancer Driver | No | 133 | 0.08026554013277 | 354 | 24 | 0.0144840072420036 | 0 |
| AMOT-203 | AMOT | Q4VCS5 | Angiomotin | chrX | GO:0001726 | Not Cancer Driver | No | 103 | 0.0950184501845018 | 911 | 85 | 0.0784132841328413 | 0 |
| APPL1-201 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | GO:0001726 | Not Cancer Driver | No | 35 | 0.0493653032440056 | 293 | 18 | 0.0253878702397743 | 1 |
| APPL2-201 | APPL2 | Q8NEU8 | DCC-interacting protein 13-beta | chr12 | GO:0001726 | Not Cancer Driver | No | 49 | 0.0737951807228915 | 149 | 8 | 0.0120481927710843 | 0 |
| ARAP3-201 | ARAP3 | Q8WWN8 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 | chr5 | GO:0001726 | Not Cancer Driver | No | 138 | 0.0893782383419689 | 580 | 55 | 0.035621761658031 | 0 |
| ARF6-201 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | GO:0001726 | Not Cancer Driver | No | 16 | 0.0914285714285714 | 5 | 0 | 0.0 | 0 |
| ARFIP2-202 | ARFIP2 | P53365 | Arfaptin-2 | chr11 | GO:0001726 | Not Cancer Driver | No | 29 | 0.0850439882697947 | 144 | 12 | 0.0351906158357771 | 0 |
| ARHGAP18-201 | ARHGAP18 | Q8N392 | Rho GTPase-activating protein 18 | chr6 | GO:0001726 | Not Cancer Driver | No | 59 | 0.0889894419306184 | 297 | 23 | 0.0346907993966817 | 0 |
| ARHGEF26-202 | ARHGEF26 | Q96DR7 | Rho guanine nucleotide exchange factor 26 | chr3 | GO:0001726 | Not Cancer Driver | No | 100 | 0.1148105625717566 | 481 | 54 | 0.0619977037887485 | 0 |
| ARHGEF7-206 | ARHGEF7 | Q14155 | Rho guanine nucleotide exchange factor 7 | chr13 | GO:0001726 | Not Cancer Driver | No | 67 | 0.0834371108343711 | 302 | 30 | 0.037359900373599 | 0 |
| ASAP3-201 | ASAP3 | Q8TDY4 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 | chr1 | GO:0001726 | Not Cancer Driver | No | 78 | 0.0863787375415282 | 389 | 36 | 0.0398671096345514 | 0 |
| ATP6V1B2-201 | ATP6V1B2 | P21281 | V-type proton ATPase subunit B, brain isoform | chr8 | GO:0001726 | Not Cancer Driver | No | 38 | 0.0743639921722113 | 49 | 3 | 0.0058708414872798 | 1 |
| BAIAP2-202 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | GO:0001726 | Not Cancer Driver | No | 60 | 0.108695652173913 | 332 | 43 | 0.0778985507246376 | 0 |
| BCAR1-201 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | GO:0001726 | Not Cancer Driver | No | 88 | 0.1011494252873563 | 681 | 64 | 0.0735632183908046 | 0 |
| CAPG-201 | CAPG | P40121 | Macrophage-capping protein | chr2 | GO:0001726 | Not Cancer Driver | No | 35 | 0.1005747126436781 | 96 | 6 | 0.0172413793103448 | 0 |
| CARMIL2-201 | CARMIL2 | Q6F5E8 | Capping protein, Arp2/3 and myosin-I linker protein 2 | chr16 | GO:0001726 | Not Cancer Driver | No | 111 | 0.0773519163763066 | 670 | 55 | 0.0383275261324041 | 4 |
| CD2AP-201 | CD2AP | Q9Y5K6 | CD2-associated protein | chr6 | GO:0001726 | Not Cancer Driver | No | 51 | 0.0798122065727699 | 458 | 38 | 0.0594679186228482 | 0 |
| CDK6-202 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | GO:0001726 | Census | Yes | 25 | 0.0766871165644171 | 24 | 3 | 0.00920245398773 | 1 |
| CLIP1-219 | CLIP1 | P30622 | CAP-Gly domain-containing linker protein 1 | chr12 | GO:0001726 | Census, Compendium | Yes | 98 | 0.0681502086230876 | 1200 | 72 | 0.0500695410292072 | 0 |
| COBL-201 | COBL | O75128 | Protein cordon-bleu | chr7 | GO:0001726 | Not Cancer Driver | No | 177 | 0.1403647898493259 | 1146 | 159 | 0.1260904044409199 | 0 |
| CSPG4-201 | CSPG4 | Q6UVK1 | Chondroitin sulfate proteoglycan 4 | chr15 | GO:0001726 | Not Cancer Driver | No | 187 | 0.0805340223944875 | 840 | 64 | 0.0275624461670973 | 0 |
| CTTN-201 | CTTN | Q14247 | Src substrate cortactin | chr11 | GO:0001726 | Not Cancer Driver | No | 55 | 0.1 | 466 | 37 | 0.0672727272727272 | 0 |
| CYFIP1-208 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | GO:0001726 | Not Cancer Driver | No | 121 | 0.0965682362330407 | 95 | 5 | 0.0039904229848363 | 0 |
| CYTH3-201 | CYTH3 | O43739 | Cytohesin-3 | chr7 | GO:0001726 | Not Cancer Driver | No | 43 | 0.1077694235588972 | 94 | 9 | 0.0225563909774436 | 0 |
| DBNL-210 | DBNL | Q9UJU6 | Drebrin-like protein | chr7 | GO:0001726 | Not Cancer Driver | No | 39 | 0.0906976744186046 | 306 | 25 | 0.0581395348837209 | 0 |
| EZR-202 | EZR | P15311 | Ezrin | chr6 | GO:0001726 | Census | Yes | 51 | 0.0870307167235494 | 296 | 26 | 0.0443686006825938 | 0 |
| FGD1-201 | FGD1 | P98174 | FYVE, RhoGEF and PH domain-containing protein 1 | chrX | GO:0001726 | Not Cancer Driver | No | 105 | 0.109261186264308 | 521 | 60 | 0.0624349635796045 | 5 |
| FGD2-201 | FGD2 | Q7Z6J4 | FYVE, RhoGEF and PH domain-containing protein 2 | chr6 | GO:0001726 | Not Cancer Driver | No | 84 | 0.1282442748091603 | 160 | 16 | 0.0244274809160305 | 0 |
| FGD3-202 | FGD3 | Q5JSP0 | FYVE, RhoGEF and PH domain-containing protein 3 | chr9 | GO:0001726 | Not Cancer Driver | No | 90 | 0.1241379310344827 | 407 | 51 | 0.0703448275862069 | 0 |
| FGD4-202 | FGD4 | Q96M96 | FYVE, RhoGEF and PH domain-containing protein 4 | chr12 | GO:0001726 | Not Cancer Driver | No | 61 | 0.0796344647519582 | 291 | 24 | 0.031331592689295 | 1 |
| FGD5-201 | FGD5 | Q6ZNL6 | FYVE, RhoGEF and PH domain-containing protein 5 | chr3 | GO:0001726 | Compendium | Yes | 197 | 0.1347469220246238 | 917 | 134 | 0.0916552667578659 | 0 |
| FGD6-201 | FGD6 | Q6ZV73 | FYVE, RhoGEF and PH domain-containing protein 6 | chr12 | GO:0001726 | Not Cancer Driver | No | 141 | 0.0986013986013986 | 809 | 79 | 0.0552447552447552 | 0 |
| FRMD4B-201 | FRMD4B | Q9Y2L6 | FERM domain-containing protein 4B | chr3 | GO:0001726 | Not Cancer Driver | No | 78 | 0.0754352030947775 | 543 | 40 | 0.0386847195357833 | 0 |
| FSCN1-201 | FSCN1 | Q16658 | Fascin | chr7 | GO:0001726 | Not Cancer Driver | No | 44 | 0.0892494929006085 | 81 | 5 | 0.0101419878296146 | 0 |
| FSCN3-201 | FSCN3 | Q9NQT6 | Fascin-3 | chr7 | GO:0001726 | Not Cancer Driver | No | 84 | 0.1686746987951807 | 6 | 0 | 0.0 | 0 |
| INPP5E-201 | INPP5E | Q9NRR6 | Phosphatidylinositol polyphosphate 5-phosphatase type IV | chr9 | GO:0001726 | Not Cancer Driver | No | 32 | 0.0496894409937888 | 273 | 9 | 0.0139751552795031 | 15 |
| INPP5J-201 | INPP5J | Q15735 | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A | chr22 | GO:0001726 | Not Cancer Driver | No | 57 | 0.0566600397614314 | 632 | 17 | 0.0168986083499005 | 0 |
| INPP5K-204 | INPP5K | Q9BT40 | Inositol polyphosphate 5-phosphatase K | chr17 | GO:0001726 | Not Cancer Driver | No | 33 | 0.0736607142857142 | 34 | 2 | 0.0044642857142857 | 7 |
| IQGAP1-201 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:0001726 | Not Cancer Driver | No | 137 | 0.0826795413397706 | 351 | 25 | 0.0150875075437537 | 0 |
| ITGA5-201 | ITGA5 | P08648 | Integrin alpha-5 | chr12 | GO:0001726 | Not Cancer Driver | No | 89 | 0.0848427073403241 | 202 | 21 | 0.0200190657769304 | 0 |
| ITGB1-201 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0001726 | Not Cancer Driver | No | 73 | 0.0914786967418546 | 84 | 8 | 0.0100250626566416 | 0 |
| ITGB1BP1-202 | ITGB1BP1 | O14713 | Integrin beta-1-binding protein 1 | chr2 | GO:0001726 | Not Cancer Driver | No | 13 | 0.065 | 58 | 1 | 0.005 | 0 |
| KIF18A-201 | KIF18A | Q8NI77 | Kinesin-like protein KIF18A | chr11 | GO:0001726 | Not Cancer Driver | No | 83 | 0.0924276169265033 | 407 | 42 | 0.0467706013363029 | 0 |
| KLHL2-201 | KLHL2 | O95198 | Kelch-like protein 2 | chr4 | GO:0001726 | Not Cancer Driver | No | 54 | 0.0910623946037099 | 43 | 2 | 0.0033726812816188 | 0 |
| KLHL41-201 | KLHL41 | O60662 | Kelch-like protein 41 | chr2 | GO:0001726 | Not Cancer Driver | No | 51 | 0.0841584158415841 | 18 | 1 | 0.0016501650165016 | 1 |
| KNSTRN-201 | KNSTRN | Q9Y448 | Small kinetochore-associated protein | chr15 | GO:0001726 | Census | Yes | 53 | 0.1677215189873417 | 248 | 47 | 0.1487341772151898 | 0 |
| LAYN-202 | LAYN | Q6UX15 | Layilin | chr11 | GO:0001726 | Not Cancer Driver | No | 46 | 0.1204188481675392 | 117 | 17 | 0.0445026178010471 | 0 |
| LCP1-201 | LCP1 | P13796 | Plastin-2 | chr13 | GO:0001726 | Census | Yes | 77 | 0.1228070175438596 | 73 | 10 | 0.0159489633173843 | 0 |
| LIMA1-201 | LIMA1 | Q9UHB6 | LIM domain and actin-binding protein 1 | chr12 | GO:0001726 | Not Cancer Driver | No | 64 | 0.0843214756258234 | 688 | 60 | 0.0790513833992094 | 0 |
| MEFV-201 | MEFV | O15553 | Pyrin | chr16 | GO:0001726 | Not Cancer Driver | No | 152 | 0.1946222791293214 | 402 | 91 | 0.11651728553137 | 43 |
| MKLN1-201 | MKLN1 | Q9UL63 | Muskelin | chr7 | GO:0001726 | Not Cancer Driver | No | 51 | 0.0693877551020408 | 91 | 9 | 0.0122448979591836 | 0 |
| MTM1-203 | MTM1 | Q13496 | Myotubularin | chrX | GO:0001726 | Not Cancer Driver | No | 84 | 0.1393034825870646 | 79 | 8 | 0.0132669983416252 | 49 |
| MTMR14-201 | MTMR14 | Q8NCE2 | Myotubularin-related protein 14 | chr3 | GO:0001726 | Not Cancer Driver | No | 45 | 0.0692307692307692 | 150 | 6 | 0.0092307692307692 | 2 |
| MTSS1-205 | MTSS1 | O43312 | Protein MTSS 1 | chr8 | GO:0001726 | Not Cancer Driver | No | 82 | 0.1086092715231788 | 583 | 68 | 0.0900662251655629 | 0 |
| MYADM-204 | MYADM | Q96S97 | Myeloid-associated differentiation marker | chr19 | GO:0001726 | Not Cancer Driver | No | 50 | 0.15527950310559 | 0 | 0 | 0.0 | 0 |
| MYH9-201 | MYH9 | P35579 | Myosin-9 | chr22 | GO:0001726 | Census, Compendium | Yes | 247 | 0.1260204081632653 | 1124 | 126 | 0.0642857142857142 | 13 |
| MYO10-210 | MYO10 | Q9HD67 | Unconventional myosin-X | chr5 | GO:0001726 | Not Cancer Driver | No | 226 | 0.1098153547133139 | 420 | 44 | 0.021379980563654 | 0 |
| MYO5A-204 | MYO5A | Q9Y4I1 | Unconventional myosin-Va | chr15 | GO:0001726 | Census, Compendium | Yes | 159 | 0.0857142857142857 | 499 | 53 | 0.0285714285714285 | 0 |
| MYO6-202 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | GO:0001726 | Not Cancer Driver | No | 92 | 0.0715953307392996 | 335 | 9 | 0.0070038910505836 | 3 |
| MYO9B-220 | MYO9B | Q13459 | Unconventional myosin-IXb | chr19 | GO:0001726 | Not Cancer Driver | No | 180 | 0.0834492350486787 | 833 | 60 | 0.0278164116828929 | 0 |
| NCKAP1-202 | NCKAP1 | Q9Y2A7 | Nck-associated protein 1 | chr2 | GO:0001726 | Not Cancer Driver | No | 96 | 0.0851063829787234 | 44 | 2 | 0.00177304964539 | 0 |
| NHERF1-201 | NHERF1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0001726 | Not Cancer Driver | No | 15 | 0.0418994413407821 | 319 | 12 | 0.0335195530726257 | 4 |
| NME2-205 | NME2 | P22392 | Nucleoside diphosphate kinase B | chr17 | GO:0001726 | Not Cancer Driver | No | 9 | 0.0592105263157894 | 11 | 0 | 0.0 | 0 |
| PAK1-202 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0001726 | Not Cancer Driver | No | 36 | 0.0660550458715596 | 300 | 19 | 0.0348623853211009 | 2 |
| PARD6A-201 | PARD6A | Q9NPB6 | Partitioning defective 6 homolog alpha | chr16 | GO:0001726 | Not Cancer Driver | No | 23 | 0.0664739884393063 | 178 | 11 | 0.0317919075144508 | 0 |
| PDLIM7-202 | PDLIM7 | Q9NR12 | PDZ and LIM domain protein 7 | chr5 | GO:0001726 | Not Cancer Driver | No | 30 | 0.0656455142231947 | 247 | 14 | 0.0306345733041575 | 0 |
| PDPN-211 | PDPN | Q86YL7 | Podoplanin | chr1 | GO:0001726 | Not Cancer Driver | No | 30 | 0.1851851851851851 | 97 | 21 | 0.1296296296296296 | 0 |
| PLCG1-202 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0001726 | Census, Compendium | Yes | 129 | 0.1 | 187 | 15 | 0.0116279069767441 | 0 |
| PODXL-202 | PODXL | O00592 | Podocalyxin | chr7 | GO:0001726 | Not Cancer Driver | No | 49 | 0.0878136200716845 | 435 | 41 | 0.0734767025089605 | 0 |
| PTK6-202 | PTK6 | Q13882 | Protein-tyrosine kinase 6 | chr20 | GO:0001726 | Census | Yes | 31 | 0.0687361419068736 | 12 | 0 | 0.0 | 0 |
| RAB22A-201 | RAB22A | Q9UL26 | Ras-related protein Rab-22A | chr20 | GO:0001726 | Not Cancer Driver | No | 18 | 0.0927835051546391 | 23 | 3 | 0.0154639175257731 | 0 |
| RAB5A-201 | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | GO:0001726 | Not Cancer Driver | No | 20 | 0.0930232558139534 | 67 | 9 | 0.041860465116279 | 0 |
| RASA1-201 | RASA1 | P20936 | Ras GTPase-activating protein 1 | chr5 | GO:0001726 | Compendium | Yes | 118 | 0.1127029608404966 | 181 | 19 | 0.0181470869149952 | 3 |
| RINL-202 | RINL | Q6ZS11 | Ras and Rab interactor-like protein | chr19 | GO:0001726 | Not Cancer Driver | No | 27 | 0.0477031802120141 | 367 | 18 | 0.0318021201413427 | 0 |
| ROCK1-201 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0001726 | Not Cancer Driver | No | 116 | 0.0856720827178729 | 780 | 61 | 0.0450516986706056 | 0 |
| S100A11-201 | S100A11 | P31949 | Protein S100-A11 | chr1 | GO:0001726 | Not Cancer Driver | No | 9 | 0.0857142857142857 | 14 | 2 | 0.019047619047619 | 0 |
| S100A6-201 | S100A6 | P06703 | Protein S100-A6 | chr1 | GO:0001726 | Not Cancer Driver | No | 5 | 0.0555555555555555 | 4 | 0 | 0.0 | 0 |
| S100B-201 | S100B | P04271 | Protein S100-B | chr21 | GO:0001726 | Not Cancer Driver | No | 8 | 0.0869565217391304 | 14 | 0 | 0.0 | 0 |
| SAMSN1-204 | SAMSN1 | Q9NSI8 | SAM domain-containing protein SAMSN-1 | chr21 | GO:0001726 | Not Cancer Driver | No | 88 | 0.2359249329758713 | 292 | 70 | 0.1876675603217158 | 0 |
| SCIMP-203 | SCIMP | Q6UWF3 | SLP adapter and CSK-interacting membrane protein | chr17 | GO:0001726 | Not Cancer Driver | No | 6 | 0.0413793103448275 | 73 | 5 | 0.0344827586206896 | 0 |
| SH2B2-201 | SH2B2 | O14492 | SH2B adapter protein 2 | chr7 | GO:0001726 | Not Cancer Driver | No | 32 | 0.050632911392405 | 356 | 12 | 0.0189873417721519 | 0 |
| SNX5-201 | SNX5 | Q9Y5X3 | Sorting nexin-5 | chr20 | GO:0001726 | Not Cancer Driver | No | 22 | 0.0544554455445544 | 93 | 8 | 0.0198019801980198 | 0 |
| SNX9-201 | SNX9 | Q9Y5X1 | Sorting nexin-9 | chr6 | GO:0001726 | Not Cancer Driver | No | 50 | 0.0840336134453781 | 233 | 19 | 0.0319327731092436 | 0 |
| TESC-201 | TESC | Q96BS2 | Calcineurin B homologous protein 3 | chr12 | GO:0001726 | Not Cancer Driver | No | 21 | 0.0981308411214953 | 73 | 6 | 0.02803738317757 | 0 |
| TLN1-201 | TLN1 | Q9Y490 | Talin-1 | chr9 | GO:0001726 | Not Cancer Driver | No | 211 | 0.0830381739472648 | 1110 | 90 | 0.0354191263282172 | 0 |
| TLN2-211 | TLN2 | Q9Y4G6 | Talin-2 | chr15 | GO:0001726 | Not Cancer Driver | No | 267 | 0.1050354051927616 | 896 | 108 | 0.042486231313926 | 0 |
| TLR4-201 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0001726 | Not Cancer Driver | No | 253 | 0.301549463647199 | 0 | 0 | 0.0 | 0 |
| TMEM87A-202 | TMEM87A | Q8NBN3 | Transmembrane protein 87A | chr15 | GO:0001726 | Not Cancer Driver | No | 46 | 0.0828828828828828 | 71 | 6 | 0.0108108108108108 | 0 |
| TRPM7-210 | TRPM7 | Q96QT4 | Transient receptor potential cation channel subfamily M member 7 | chr15 | GO:0001726 | Not Cancer Driver | No | 133 | 0.071313672922252 | 456 | 37 | 0.0198391420911528 | 1 |
| VIL1-201 | VIL1 | P09327 | Villin-1 | chr2 | GO:0001726 | Not Cancer Driver | No | 90 | 0.1088270858524788 | 222 | 26 | 0.0314389359129383 | 0 |
| WASF2-202 | WASF2 | Q9Y6W5 | Actin-binding protein WASF2 | chr1 | GO:0001726 | Not Cancer Driver | No | 36 | 0.072289156626506 | 400 | 22 | 0.0441767068273092 | 0 |
| WIPF1-217 | WIPF1 | O43516 | WAS/WASL-interacting protein family member 1 | chr2 | GO:0001726 | Not Cancer Driver | No | 88 | 0.1749502982107356 | 505 | 88 | 0.1749502982107356 | 0 |