Total number of protein in "GO:0001755" GO term: 44
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1-207 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0001755 | Census, Compendium | Yes | 71 | 0.1394891944990176 | 21 | 8 | 0.0157170923379174 | 6 |
| CORO1C-201 | CORO1C | Q9ULV4 | Coronin-1C | chr12 | GO:0001755 | Not Cancer Driver | No | 41 | 0.0864978902953586 | 84 | 12 | 0.0253164556962025 | 0 |
| EDN3-202 | EDN3 | P14138 | Endothelin-3 | chr20 | GO:0001755 | Not Cancer Driver | No | 51 | 0.2142857142857142 | 140 | 36 | 0.1512605042016806 | 3 |
| EDNRB-207 | EDNRB | P24530 | Endothelin receptor type B | chr13 | GO:0001755 | Not Cancer Driver | No | 94 | 0.2126696832579185 | 56 | 13 | 0.0294117647058823 | 9 |
| EFNB1-201 | EFNB1 | P98172 | Ephrin-B1 | chrX | GO:0001755 | Not Cancer Driver | No | 35 | 0.1011560693641618 | 126 | 10 | 0.0289017341040462 | 14 |
| ERBB4-202 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0001755 | Census, Compendium | Yes | 376 | 0.2874617737003058 | 324 | 95 | 0.0726299694189602 | 2 |
| GBX2-201 | GBX2 | P52951 | Homeobox protein GBX-2 | chr2 | GO:0001755 | Not Cancer Driver | No | 31 | 0.0890804597701149 | 247 | 24 | 0.0689655172413793 | 0 |
| GDNF-201 | GDNF | P39905 | Glial cell line-derived neurotrophic factor | chr5 | GO:0001755 | Not Cancer Driver | No | 43 | 0.2037914691943128 | 83 | 16 | 0.0758293838862559 | 2 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0001755 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| HTR2B-201 | HTR2B | P41595 | 5-hydroxytryptamine receptor 2B | chr2 | GO:0001755 | Not Cancer Driver | No | 25 | 0.0519750519750519 | 23 | 0 | 0.0 | 0 |
| ISL1-201 | ISL1 | P61371 | Insulin gene enhancer protein ISL-1 | chr5 | GO:0001755 | Not Cancer Driver | No | 73 | 0.2091690544412607 | 181 | 41 | 0.1174785100286533 | 0 |
| KITLG-205 | KITLG | P21583 | Kit ligand | chr12 | GO:0001755 | Not Cancer Driver | No | 38 | 0.1391941391941392 | 61 | 6 | 0.0219780219780219 | 1 |
| NRP1-206 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0001755 | Compendium | Yes | 112 | 0.1213434452871072 | 212 | 25 | 0.0270855904658721 | 0 |
| NRTN-201 | NRTN | Q99748 | Neurturin | chr19 | GO:0001755 | Not Cancer Driver | No | 6 | 0.0304568527918781 | 26 | 0 | 0.0 | 0 |
| OVOL2-201 | OVOL2 | Q9BRP0 | Transcription factor Ovo-like 2 | chr20 | GO:0001755 | Not Cancer Driver | No | 28 | 0.1018181818181818 | 141 | 5 | 0.0181818181818181 | 0 |
| PAX6-203 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0001755 | Not Cancer Driver | No | 51 | 0.1208530805687203 | 338 | 37 | 0.0876777251184834 | 35 |
| PHACTR4-202 | PHACTR4 | Q8IZ21 | Phosphatase and actin regulator 4 | chr1 | GO:0001755 | Not Cancer Driver | No | 58 | 0.0826210826210826 | 678 | 54 | 0.0769230769230769 | 0 |
| RADIL-201 | RADIL | Q96JH8 | Ras-associating and dilute domain-containing protein | chr7 | GO:0001755 | Not Cancer Driver | No | 121 | 0.1125581395348837 | 387 | 41 | 0.0381395348837209 | 0 |
| RET-202 | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | GO:0001755 | Census, Compendium | Yes | 176 | 0.1579892280071813 | 108 | 11 | 0.0098743267504488 | 91 |
| SEMA3A-201 | SEMA3A | Q14563 | Semaphorin-3A | chr7 | GO:0001755 | Not Cancer Driver | No | 155 | 0.2010376134889753 | 165 | 38 | 0.0492866407263294 | 10 |
| SEMA3B-212 | SEMA3B | Q13214 | Semaphorin-3B | chr3 | GO:0001755 | Not Cancer Driver | No | 0 | 0.0 | 145 | 0 | 0.0 | 0 |
| SEMA3C-201 | SEMA3C | Q99985 | Semaphorin-3C | chr7 | GO:0001755 | Not Cancer Driver | No | 102 | 0.1358189081225033 | 112 | 17 | 0.0226364846870838 | 0 |
| SEMA3D-201 | SEMA3D | O95025 | Semaphorin-3D | chr7 | GO:0001755 | Not Cancer Driver | No | 160 | 0.2059202059202059 | 101 | 36 | 0.0463320463320463 | 0 |
| SEMA3E-204 | SEMA3E | O15041 | Semaphorin-3E | chr7 | GO:0001755 | Not Cancer Driver | No | 162 | 0.2090322580645161 | 87 | 24 | 0.0309677419354838 | 0 |
| SEMA3F-201 | SEMA3F | Q13275 | Semaphorin-3F | chr3 | GO:0001755 | Not Cancer Driver | No | 86 | 0.1095541401273885 | 195 | 25 | 0.0318471337579617 | 0 |
| SEMA3G-201 | SEMA3G | Q9NS98 | Semaphorin-3G | chr3 | GO:0001755 | Not Cancer Driver | No | 82 | 0.1048593350383631 | 206 | 27 | 0.0345268542199488 | 0 |
| SEMA4A-204 | SEMA4A | Q9H3S1 | Semaphorin-4A | chr1 | GO:0001755 | Not Cancer Driver | No | 101 | 0.1327201051248357 | 122 | 17 | 0.0223390275952693 | 4 |
| SEMA4B-202 | SEMA4B | Q9NPR2 | Semaphorin-4B | chr15 | GO:0001755 | Not Cancer Driver | No | 73 | 0.087216248506571 | 107 | 14 | 0.016726403823178 | 0 |
| SEMA4C-201 | SEMA4C | Q9C0C4 | Semaphorin-4C | chr2 | GO:0001755 | Not Cancer Driver | No | 81 | 0.0972388955582232 | 149 | 15 | 0.0180072028811524 | 0 |
| SEMA4D-208 | SEMA4D | Q92854 | Semaphorin-4D | chr9 | GO:0001755 | Not Cancer Driver | No | 93 | 0.1078886310904872 | 132 | 14 | 0.0162412993039443 | 0 |
| SEMA4F-202 | SEMA4F | O95754 | Semaphorin-4F | chr2 | GO:0001755 | Not Cancer Driver | No | 90 | 0.1168831168831168 | 140 | 12 | 0.0155844155844155 | 0 |
| SEMA4G-210 | SEMA4G | Q9NTN9 | Semaphorin-4G | chr10 | GO:0001755 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 0 |
| SEMA5A-201 | SEMA5A | Q13591 | Semaphorin-5A | chr5 | GO:0001755 | Not Cancer Driver | No | 221 | 0.2057728119180633 | 24 | 2 | 0.0018621973929236 | 0 |
| SEMA5B-202 | SEMA5B | Q9P283 | Semaphorin-5B | chr3 | GO:0001755 | Not Cancer Driver | No | 198 | 0.1720243266724587 | 163 | 16 | 0.0139009556907037 | 0 |
| SEMA6A-202 | SEMA6A | Q9H2E6 | Semaphorin-6A | chr5 | GO:0001755 | Not Cancer Driver | No | 99 | 0.0961165048543689 | 458 | 49 | 0.0475728155339805 | 0 |
| SEMA6B-201 | SEMA6B | Q9H3T3 | Semaphorin-6B | chr19 | GO:0001755 | Not Cancer Driver | No | 66 | 0.0743243243243243 | 340 | 17 | 0.0191441441441441 | 0 |
| SEMA6C-204 | SEMA6C | Q9H3T2 | Semaphorin-6C | chr1 | GO:0001755 | Not Cancer Driver | No | 93 | 0.1 | 413 | 22 | 0.0236559139784946 | 0 |
| SEMA6D-207 | SEMA6D | Q8NFY4 | Semaphorin-6D | chr15 | GO:0001755 | Not Cancer Driver | No | 162 | 0.1509785647716682 | 476 | 75 | 0.0698974836905871 | 0 |
| SEMA7A-201 | SEMA7A | O75326 | Semaphorin-7A | chr15 | GO:0001755 | Not Cancer Driver | No | 64 | 0.0960960960960961 | 150 | 19 | 0.0285285285285285 | 1 |
| SHH-201 | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0001755 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 139 | 11 | 0.0238095238095238 | 69 |
| SMO-201 | SMO | Q99835 | Protein smoothened | chr7 | GO:0001755 | Census, Compendium | Yes | 88 | 0.1118170266836086 | 242 | 20 | 0.025412960609911 | 1 |
| SOX10-202 | SOX10 | P56693 | Transcription factor SOX-10 | chr22 | GO:0001755 | Not Cancer Driver | No | 58 | 0.1244635193133047 | 424 | 55 | 0.1180257510729613 | 12 |
| SOX8-201 | SOX8 | P57073 | Transcription factor SOX-8 | chr16 | GO:0001755 | Not Cancer Driver | No | 38 | 0.085201793721973 | 403 | 35 | 0.0784753363228699 | 0 |
| TBX1-201 | TBX1 | O43435 | T-box transcription factor TBX1 | chr22 | GO:0001755 | Not Cancer Driver | No | 13 | 0.0326633165829145 | 198 | 1 | 0.0025125628140703 | 4 |