Total number of protein in "GO:0001784" GO term: 48
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0001784 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
ABL2-203 | ABL2 | P42684 | Tyrosine-protein kinase ABL2 | chr1 | GO:0001784 | Census, Compendium | Yes | 125 | 0.1057529610829103 | 644 | 53 | 0.0448392554991539 | 0 |
BCAR3-201 | BCAR3 | O75815 | Breast cancer anti-estrogen resistance protein 3 | chr1 | GO:0001784 | Not Cancer Driver | No | 74 | 0.0896969696969696 | 397 | 34 | 0.0412121212121212 | 0 |
CBL-201 | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0001784 | Census, Compendium | Yes | 84 | 0.0927152317880794 | 513 | 44 | 0.0485651214128035 | 4 |
CBLB-201 | CBLB | Q13191 | E3 ubiquitin-protein ligase CBL-B | chr3 | GO:0001784 | Census | Yes | 126 | 0.1283095723014256 | 565 | 77 | 0.0784114052953156 | 0 |
CBLC-203 | CBLC | Q9ULV8 | E3 ubiquitin-protein ligase CBL-C | chr19 | GO:0001784 | Census | Yes | 43 | 0.090717299578059 | 126 | 12 | 0.0253164556962025 | 0 |
CRK-201 | CRK | P46108 | Adapter molecule crk | chr17 | GO:0001784 | Not Cancer Driver | No | 24 | 0.0789473684210526 | 197 | 19 | 0.0625 | 0 |
CRKL-201 | CRKL | P46109 | Crk-like protein | chr22 | GO:0001784 | Not Cancer Driver | No | 24 | 0.0792079207920792 | 160 | 17 | 0.0561056105610561 | 0 |
ENST00000593731 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0001784 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
FGR-203 | FGR | P09769 | Tyrosine-protein kinase Fgr | chr1 | GO:0001784 | Not Cancer Driver | No | 67 | 0.1266540642722117 | 52 | 6 | 0.0113421550094517 | 0 |
GRAP-201 | GRAP | Q13588 | GRB2-related adapter protein | chr17 | GO:0001784 | Not Cancer Driver | No | 9 | 0.0414746543778801 | 0 | 0 | 0.0 | 1 |
GRAP2-201 | GRAP2 | O75791 | GRB2-related adapter protein 2 | chr22 | GO:0001784 | Not Cancer Driver | No | 49 | 0.1484848484848485 | 151 | 16 | 0.0484848484848484 | 0 |
GRB2-202 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0001784 | Not Cancer Driver | No | 21 | 0.0967741935483871 | 10 | 0 | 0.0 | 0 |
HCK-202 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0001784 | Not Cancer Driver | No | 89 | 0.1692015209125475 | 124 | 22 | 0.0418250950570342 | 0 |
IRS1-201 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0001784 | Not Cancer Driver | No | 118 | 0.0950080515297906 | 1075 | 104 | 0.0837359098228663 | 2 |
LCK-202 | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | GO:0001784 | Census | Yes | 76 | 0.1493123772102161 | 95 | 12 | 0.0235756385068762 | 1 |
LDLRAP1-201 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0001784 | Not Cancer Driver | No | 29 | 0.0941558441558441 | 121 | 9 | 0.0292207792207792 | 2 |
MAPK1-201 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | GO:0001784 | Census, Compendium | Yes | 52 | 0.1444444444444444 | 2 | 0 | 0.0 | 6 |
MAPK3-201 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0001784 | Not Cancer Driver | No | 32 | 0.0844327176781002 | 49 | 3 | 0.0079155672823219 | 0 |
NCK2-201 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0001784 | Not Cancer Driver | No | 66 | 0.1736842105263158 | 88 | 15 | 0.0394736842105263 | 0 |
PFN1-201 | PFN1 | P07737 | Profilin-1 | chr17 | GO:0001784 | Not Cancer Driver | No | 13 | 0.0928571428571428 | 7 | 1 | 0.0071428571428571 | 3 |
PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0001784 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
PIK3R2-201 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0001784 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
PIK3R3-201 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | GO:0001784 | Not Cancer Driver | No | 42 | 0.0911062906724512 | 149 | 17 | 0.0368763557483731 | 0 |
PLCG2-206 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0001784 | Not Cancer Driver | No | 183 | 0.1446640316205533 | 144 | 18 | 0.0142292490118577 | 1 |
PTPN11-201 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0001784 | Census, Compendium | Yes | 92 | 0.1551433389544688 | 260 | 27 | 0.0455311973018549 | 44 |
PTPN3-202 | PTPN3 | P26045 | Tyrosine-protein phosphatase non-receptor type 3 | chr9 | GO:0001784 | Not Cancer Driver | No | 105 | 0.1150054764512595 | 214 | 24 | 0.0262869660460021 | 0 |
PTPN5-201 | PTPN5 | P54829 | Tyrosine-protein phosphatase non-receptor type 5 | chr11 | GO:0001784 | Not Cancer Driver | No | 78 | 0.1380530973451327 | 163 | 23 | 0.0407079646017699 | 0 |
PTPN6-201 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | GO:0001784 | Census, Compendium | Yes | 52 | 0.0873949579831932 | 194 | 20 | 0.0336134453781512 | 0 |
RASA1-201 | RASA1 | P20936 | Ras GTPase-activating protein 1 | chr5 | GO:0001784 | Compendium | Yes | 118 | 0.1127029608404966 | 181 | 19 | 0.0181470869149952 | 3 |
SAMSN1-204 | SAMSN1 | Q9NSI8 | SAM domain-containing protein SAMSN-1 | chr21 | GO:0001784 | Not Cancer Driver | No | 88 | 0.2359249329758713 | 292 | 70 | 0.1876675603217158 | 0 |
SH2D3A-201 | SH2D3A | Q9BRG2 | SH2 domain-containing protein 3A | chr19 | GO:0001784 | Not Cancer Driver | No | 52 | 0.0902777777777777 | 308 | 30 | 0.0520833333333333 | 0 |
SH2D3C-201 | SH2D3C | Q8N5H7 | SH2 domain-containing protein 3C | chr9 | GO:0001784 | Not Cancer Driver | No | 81 | 0.0941860465116279 | 443 | 52 | 0.0604651162790697 | 0 |
SH3BP2-206 | SH3BP2 | P78314 | SH3 domain-binding protein 2 | chr4 | GO:0001784 | Not Cancer Driver | No | 52 | 0.0926916221033868 | 356 | 32 | 0.0570409982174688 | 3 |
SHB-201 | SHB | Q15464 | SH2 domain-containing adapter protein B | chr9 | GO:0001784 | Not Cancer Driver | No | 42 | 0.0825147347740668 | 338 | 29 | 0.0569744597249508 | 0 |
SHC1-202 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0001784 | Not Cancer Driver | No | 58 | 0.0994854202401372 | 400 | 41 | 0.0703259005145797 | 0 |
SHC3-202 | SHC3 | Q92529 | SHC-transforming protein 3 | chr9 | GO:0001784 | Not Cancer Driver | No | 68 | 0.1144781144781144 | 433 | 48 | 0.0808080808080808 | 0 |
SHD-201 | SHD | Q96IW2 | SH2 domain-containing adapter protein D | chr19 | GO:0001784 | Not Cancer Driver | No | 47 | 0.138235294117647 | 271 | 30 | 0.088235294117647 | 0 |
SHE-201 | SHE | Q5VZ18 | SH2 domain-containing adapter protein E | chr1 | GO:0001784 | Not Cancer Driver | No | 50 | 0.101010101010101 | 408 | 43 | 0.0868686868686868 | 0 |
SHF-201 | SHF | Q7M4L6 | SH2 domain-containing adapter protein F | chr15 | GO:0001784 | Not Cancer Driver | No | 38 | 0.0898345153664302 | 348 | 31 | 0.0732860520094562 | 0 |
SLA-201 | SLA | Q13239 | Src-like-adapter | chr8 | GO:0001784 | Not Cancer Driver | No | 43 | 0.1557971014492753 | 51 | 8 | 0.0289855072463768 | 0 |
SOCS3-201 | SOCS3 | O14543 | Suppressor of cytokine signaling 3 | chr17 | GO:0001784 | Not Cancer Driver | No | 24 | 0.1066666666666666 | 111 | 11 | 0.0488888888888888 | 0 |
STAP1-201 | STAP1 | Q9ULZ2 | Signal-transducing adaptor protein 1 | chr4 | GO:0001784 | Not Cancer Driver | No | 46 | 0.1559322033898305 | 105 | 12 | 0.0406779661016949 | 0 |
SYK-204 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0001784 | Census | Yes | 75 | 0.1181102362204724 | 131 | 20 | 0.0314960629921259 | 4 |
VAV1-210 | VAV1 | P15498 | Proto-oncogene vav | chr19 | GO:0001784 | Census, Compendium | Yes | 128 | 0.1514792899408284 | 113 | 18 | 0.0213017751479289 | 0 |
VAV2-201 | VAV2 | P52735 | Guanine nucleotide exchange factor VAV2 | chr9 | GO:0001784 | Not Cancer Driver | No | 85 | 0.0968109339407744 | 136 | 15 | 0.0170842824601366 | 0 |
YES1-201 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | GO:0001784 | Not Cancer Driver | No | 48 | 0.0883977900552486 | 63 | 9 | 0.0165745856353591 | 0 |
ZAP70-201 | ZAP70 | P43403 | Tyrosine-protein kinase ZAP-70 | chr2 | GO:0001784 | Not Cancer Driver | No | 90 | 0.1453957996768982 | 119 | 13 | 0.0210016155088853 | 7 |