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Total number of protein in "GO:0001784" GO term:  48

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1-201 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0001784 Census, Compendium Yes 106 0.0938053097345132 609 53 0.0469026548672566 2
ABL2-203 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0001784 Census, Compendium Yes 125 0.1057529610829103 644 53 0.0448392554991539 0
BCAR3-201 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0001784 Not Cancer Driver No 74 0.0896969696969696 397 34 0.0412121212121212 0
CBL-201 CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0001784 Census, Compendium Yes 84 0.0927152317880794 513 44 0.0485651214128035 4
CBLB-201 CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0001784 Census Yes 126 0.1283095723014256 565 77 0.0784114052953156 0
CBLC-203 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 GO:0001784 Census Yes 43 0.090717299578059 126 12 0.0253164556962025 0
CRK-201 CRK P46108 Adapter molecule crk chr17 GO:0001784 Not Cancer Driver No 24 0.0789473684210526 197 19 0.0625 0
CRKL-201 CRKL P46109 Crk-like protein chr22 GO:0001784 Not Cancer Driver No 24 0.0792079207920792 160 17 0.0561056105610561 0
ENST00000593731 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0001784 Not Cancer Driver No 83 0.114010989010989 418 40 0.0549450549450549 3
FGR-203 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0001784 Not Cancer Driver No 67 0.1266540642722117 52 6 0.0113421550094517 0
GRAP-201 GRAP Q13588 GRB2-related adapter protein chr17 GO:0001784 Not Cancer Driver No 9 0.0414746543778801 0 0 0.0 1
GRAP2-201 GRAP2 O75791 GRB2-related adapter protein 2 chr22 GO:0001784 Not Cancer Driver No 49 0.1484848484848485 151 16 0.0484848484848484 0
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0001784 Not Cancer Driver No 21 0.0967741935483871 10 0 0.0 0
HCK-202 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0001784 Not Cancer Driver No 89 0.1692015209125475 124 22 0.0418250950570342 0
IRS1-201 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0001784 Not Cancer Driver No 118 0.0950080515297906 1075 104 0.0837359098228663 2
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0001784 Census Yes 76 0.1493123772102161 95 12 0.0235756385068762 1
LDLRAP1-201 LDLRAP1 Q5SW96 Low density lipoprotein receptor adapter protein 1 chr1 GO:0001784 Not Cancer Driver No 29 0.0941558441558441 121 9 0.0292207792207792 2
MAPK1-201 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0001784 Census, Compendium Yes 52 0.1444444444444444 2 0 0.0 6
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0001784 Not Cancer Driver No 32 0.0844327176781002 49 3 0.0079155672823219 0
NCK2-201 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0001784 Not Cancer Driver No 66 0.1736842105263158 88 15 0.0394736842105263 0
PFN1-201 PFN1 P07737 Profilin-1 chr17 GO:0001784 Not Cancer Driver No 13 0.0928571428571428 7 1 0.0071428571428571 3
PIK3R1-211 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0001784 Census, Compendium Yes 122 0.1685082872928177 271 50 0.0690607734806629 2
PIK3R2-201 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0001784 Not Cancer Driver No 83 0.114010989010989 418 40 0.0549450549450549 3
PIK3R3-201 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 GO:0001784 Not Cancer Driver No 42 0.0911062906724512 149 17 0.0368763557483731 0
PLCG2-206 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0001784 Not Cancer Driver No 183 0.1446640316205533 144 18 0.0142292490118577 1
PTPN11-201 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0001784 Census, Compendium Yes 92 0.1551433389544688 260 27 0.0455311973018549 44
PTPN3-202 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0001784 Not Cancer Driver No 105 0.1150054764512595 214 24 0.0262869660460021 0
PTPN5-201 PTPN5 P54829 Tyrosine-protein phosphatase non-receptor type 5 chr11 GO:0001784 Not Cancer Driver No 78 0.1380530973451327 163 23 0.0407079646017699 0
PTPN6-201 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0001784 Census, Compendium Yes 52 0.0873949579831932 194 20 0.0336134453781512 0
RASA1-201 RASA1 P20936 Ras GTPase-activating protein 1 chr5 GO:0001784 Compendium Yes 118 0.1127029608404966 181 19 0.0181470869149952 3
SAMSN1-204 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 GO:0001784 Not Cancer Driver No 88 0.2359249329758713 292 70 0.1876675603217158 0
SH2D3A-201 SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 GO:0001784 Not Cancer Driver No 52 0.0902777777777777 308 30 0.0520833333333333 0
SH2D3C-201 SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0001784 Not Cancer Driver No 81 0.0941860465116279 443 52 0.0604651162790697 0
SH3BP2-206 SH3BP2 P78314 SH3 domain-binding protein 2 chr4 GO:0001784 Not Cancer Driver No 52 0.0926916221033868 356 32 0.0570409982174688 3
SHB-201 SHB Q15464 SH2 domain-containing adapter protein B chr9 GO:0001784 Not Cancer Driver No 42 0.0825147347740668 338 29 0.0569744597249508 0
SHC1-202 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0001784 Not Cancer Driver No 58 0.0994854202401372 400 41 0.0703259005145797 0
SHC3-202 SHC3 Q92529 SHC-transforming protein 3 chr9 GO:0001784 Not Cancer Driver No 68 0.1144781144781144 433 48 0.0808080808080808 0
SHD-201 SHD Q96IW2 SH2 domain-containing adapter protein D chr19 GO:0001784 Not Cancer Driver No 47 0.138235294117647 271 30 0.088235294117647 0
SHE-201 SHE Q5VZ18 SH2 domain-containing adapter protein E chr1 GO:0001784 Not Cancer Driver No 50 0.101010101010101 408 43 0.0868686868686868 0
SHF-201 SHF Q7M4L6 SH2 domain-containing adapter protein F chr15 GO:0001784 Not Cancer Driver No 38 0.0898345153664302 348 31 0.0732860520094562 0
SLA-201 SLA Q13239 Src-like-adapter chr8 GO:0001784 Not Cancer Driver No 43 0.1557971014492753 51 8 0.0289855072463768 0
SOCS3-201 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0001784 Not Cancer Driver No 24 0.1066666666666666 111 11 0.0488888888888888 0
STAP1-201 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0001784 Not Cancer Driver No 46 0.1559322033898305 105 12 0.0406779661016949 0
SYK-204 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0001784 Census Yes 75 0.1181102362204724 131 20 0.0314960629921259 4
VAV1-210 VAV1 P15498 Proto-oncogene vav chr19 GO:0001784 Census, Compendium Yes 128 0.1514792899408284 113 18 0.0213017751479289 0
VAV2-201 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0001784 Not Cancer Driver No 85 0.0968109339407744 136 15 0.0170842824601366 0
YES1-201 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0001784 Not Cancer Driver No 48 0.0883977900552486 63 9 0.0165745856353591 0
ZAP70-201 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0001784 Not Cancer Driver No 90 0.1453957996768982 119 13 0.0210016155088853 7