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Total number of protein in "GO:0001822" GO term:  115

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACE-202 ACE P12821 Angiotensin-converting enzyme chr17 GO:0001822 Not Cancer Driver No 152 0.116385911179173 87 5 0.0038284839203675 0
ACVR2B-201 ACVR2B Q13705 Activin receptor type-2B chr3 GO:0001822 Not Cancer Driver No 55 0.107421875 70 11 0.021484375 2
ADAMTS1-201 ADAMTS1 Q9UHI8 A disintegrin and metalloproteinase with thrombospondin motifs 1 chr21 GO:0001822 Not Cancer Driver No 101 0.1044467425025853 275 26 0.0268872802481902 0
ADAMTS6-203 ADAMTS6 Q9UKP5 A disintegrin and metalloproteinase with thrombospondin motifs 6 chr5 GO:0001822 Not Cancer Driver No 100 0.0895255147717099 75 7 0.0062667860340196 0
AGT-201 AGT P01019 Angiotensinogen chr1 GO:0001822 Not Cancer Driver No 61 0.1281512605042016 33 3 0.0063025210084033 1
AGTR1-201 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0001822 Not Cancer Driver No 70 0.1949860724233983 0 0 0.0 1
ALDH1A2-201 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0001822 Not Cancer Driver No 72 0.138996138996139 56 12 0.0231660231660231 3
ANKS6-201 ANKS6 Q68DC2 Ankyrin repeat and SAM domain-containing protein 6 chr9 GO:0001822 Not Cancer Driver No 70 0.0803673938002296 572 46 0.052812858783008 2
AP1B1-202 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 GO:0001822 Not Cancer Driver No 84 0.0885142255005268 119 7 0.0073761854583772 1
AP2B1-221 AP2B1 P63010 AP-2 complex subunit beta chr17 GO:0001822 Not Cancer Driver No 80 0.0853788687299893 95 8 0.0085378868729989 0
APAF1-210 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0001822 Not Cancer Driver No 91 0.0729166666666666 17 1 0.000801282051282 0
ARID5B-201 ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 GO:0001822 Not Cancer Driver No 133 0.1119528619528619 770 82 0.069023569023569 0
ARL3-201 ARL3 P36405 ADP-ribosylation factor-like protein 3 chr10 GO:0001822 Not Cancer Driver No 13 0.0714285714285714 0 0 0.0 1
ASS1-201 ASS1 P00966 Argininosuccinate synthase chr9 GO:0001822 Not Cancer Driver No 50 0.1213592233009708 63 8 0.0194174757281553 66
BAG6-237 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0001822 Not Cancer Driver No 73 0.0648312611012433 856 59 0.0523978685612788 0
BAX-202 BAX Q07812 Apoptosis regulator BAX chr19 GO:0001822 Census Yes 24 0.125 39 2 0.0104166666666666 0
BCL2L11-204 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0001822 Not Cancer Driver No 37 0.1868686868686868 131 16 0.0808080808080808 0
BICC1-202 BICC1 Q9H694 Protein bicaudal C homolog 1 chr10 GO:0001822 Not Cancer Driver No 139 0.1427104722792607 648 95 0.0975359342915811 1
BMP10-201 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0001822 Not Cancer Driver No 69 0.1627358490566037 87 10 0.0235849056603773 0
BMP4-201 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0001822 Not Cancer Driver No 69 0.1691176470588235 142 20 0.0490196078431372 5
BMP6-201 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0001822 Not Cancer Driver No 79 0.1539961013645224 228 41 0.0799220272904483 6
C1GALT1-204 C1GALT1 Q9NS00 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 chr7 GO:0001822 Not Cancer Driver No 31 0.0853994490358126 69 4 0.0110192837465564 0
CASP9-201 CASP9 P55211 Caspase-9 chr1 GO:0001822 Census Yes 26 0.0625 71 7 0.016826923076923 0
CC2D2A-202 CC2D2A Q9P2K1 Coiled-coil and C2 domain-containing protein 2A chr4 GO:0001822 Not Cancer Driver No 107 0.0660493827160493 679 58 0.0358024691358024 22
CD2AP-201 CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0001822 Not Cancer Driver No 51 0.0798122065727699 458 38 0.0594679186228482 0
CDKN1C-203 CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0001822 Not Cancer Driver No 3 0.0094936708860759 256 1 0.0031645569620253 6
CENPF-201 CENPF P49454 Centromere protein F chr1 GO:0001822 Not Cancer Driver No 272 0.0873474630700064 2158 181 0.0581245985870263 0
CEP290-207 CEP290 O15078 Centrosomal protein of 290 kDa chr12 GO:0001822 Not Cancer Driver No 158 0.063735377168213 1424 94 0.0379185155304558 3
CNTRL-205 CNTRL Q7Z7A1 Centriolin chr9 GO:0001822 Census Yes 166 0.0713978494623655 1560 115 0.0494623655913978 0
CYP26A1-201 CYP26A1 O43174 Cytochrome P450 26A1 chr10 GO:0001822 Not Cancer Driver No 57 0.1146881287726358 9 1 0.0020120724346076 0
CYP26B1-201 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0001822 Not Cancer Driver No 91 0.177734375 10 2 0.00390625 2
CYP4A11-201 CYP4A11 Q02928 Cytochrome P450 4A11 chr1 GO:0001822 Not Cancer Driver No 95 0.1830443159922928 25 5 0.0096339113680154 0
CYP4A22-203 CYP4A22 Q5TCH4 Cytochrome P450 4A22 chr1 GO:0001822 Not Cancer Driver No 82 0.1579961464354528 26 5 0.0096339113680154 0
DDC-207 DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 GO:0001822 Not Cancer Driver No 79 0.1645833333333333 5 0 0.0 9
DYNC2H1-202 DYNC2H1 Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 chr11 GO:0001822 Not Cancer Driver No 378 0.0877641049454376 285 9 0.0020896215463199 34
FADD-201 FADD Q13158 FAS-associated death domain protein chr11 GO:0001822 Not Cancer Driver No 24 0.1153846153846153 45 9 0.0432692307692307 1
FOXC1-201 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0001822 Not Cancer Driver No 23 0.0415913200723327 409 14 0.0253164556962025 25
FREM2-201 FREM2 Q5SZK8 FRAS1-related extracellular matrix protein 2 chr13 GO:0001822 Not Cancer Driver No 435 0.1372672767434521 787 121 0.0381823919217418 3
GATA3-201 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0001822 Census, Compendium Yes 99 0.2234762979683973 368 79 0.1783295711060948 2
GFRA1-201 GFRA1 P56159 GDNF family receptor alpha-1 chr10 GO:0001822 Not Cancer Driver No 99 0.2129032258064516 43 9 0.0193548387096774 0
GLI2-209 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0001822 Not Cancer Driver No 235 0.148171500630517 1407 200 0.1261034047919293 2
GREB1L-202 GREB1L Q9C091 GREB1-like protein chr18 GO:0001822 Not Cancer Driver No 57 0.0296411856474258 480 13 0.0067602704108164 24
HAS2-201 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0001822 Not Cancer Driver No 74 0.1340579710144927 17 1 0.0018115942028985 0
HELLS-201 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0001822 Not Cancer Driver No 52 0.0620525059665871 228 16 0.0190930787589498 0
HMGCS2-201 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0001822 Not Cancer Driver No 65 0.1279527559055118 29 2 0.0039370078740157 19
HNF1B-203 HNF1B P35680 Hepatocyte nuclear factor 1-beta chr17 GO:0001822 Not Cancer Driver No 68 0.1220825852782764 476 57 0.1023339317773788 19
HPGD-202 HPGD P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] chr4 GO:0001822 Not Cancer Driver No 19 0.0714285714285714 4 1 0.0037593984962406 2
HYAL2-201 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0001822 Not Cancer Driver No 46 0.0972515856236786 8 1 0.0021141649048625 0
IFT20-203 IFT20 Q8IY31 Intraflagellar transport protein 20 homolog chr17 GO:0001822 Not Cancer Driver No 11 0.0833333333333333 0 0 0.0 0
IFT25-201 IFT25 Q9Y547 Intraflagellar transport protein 25 homolog chr1 GO:0001822 Not Cancer Driver No 13 0.0902777777777777 27 2 0.0138888888888888 0
IFT27-205 IFT27 Q9BW83 Intraflagellar transport protein 27 homolog chr22 GO:0001822 Not Cancer Driver No 14 0.075268817204301 0 0 0.0 1
IFT88-202 IFT88 Q13099 Intraflagellar transport protein 88 homolog chr13 GO:0001822 Not Cancer Driver No 70 0.0849514563106796 281 23 0.0279126213592233 0
ITGA8-201 ITGA8 P53708 Integrin alpha-8 chr10 GO:0001822 Not Cancer Driver No 224 0.2107243650047036 114 25 0.0235183443085606 1
JMJD6-202 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0001822 Not Cancer Driver No 42 0.1042183622828784 133 18 0.0446650124069478 0
KCNJ8-201 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0001822 Not Cancer Driver No 78 0.1839622641509433 69 17 0.0400943396226415 1
LHX1-201 LHX1 P48742 LIM/homeobox protein Lhx1 chr17 GO:0001822 Not Cancer Driver No 37 0.0911330049261083 268 23 0.0566502463054187 0
LRP2-205 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0001822 Not Cancer Driver No 740 0.158968850698174 209 26 0.0055853920515574 1
LRP4-201 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0001822 Not Cancer Driver No 192 0.1007874015748031 267 22 0.0115485564304461 11
MME-201 MME P08473 Neprilysin chr3 GO:0001822 Not Cancer Driver No 156 0.208 40 17 0.0226666666666666 4
MMP17-201 MMP17 Q9ULZ9 Matrix metalloproteinase-17 chr12 GO:0001822 Not Cancer Driver No 76 0.1260364842454394 244 23 0.0381426202321724 0
MPST-201 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 GO:0001822 Not Cancer Driver No 18 0.0606060606060606 72 9 0.0303030303030303 0
NLE1-202 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 GO:0001822 Not Cancer Driver No 43 0.088659793814433 21 2 0.0041237113402061 0
NPHP3-201 NPHP3 Q7Z494 Nephrocystin-3 chr3 GO:0001822 Not Cancer Driver No 89 0.0669172932330827 250 24 0.0180451127819548 7
ODC1-201 ODC1 P11926 Ornithine decarboxylase chr2 GO:0001822 Not Cancer Driver No 32 0.0694143167028199 33 5 0.0108459869848156 0
OVOL1-201 OVOL1 O14753 Putative transcription factor Ovo-like 1 chr11 GO:0001822 Not Cancer Driver No 25 0.0936329588014981 70 11 0.0411985018726591 0
PAX8-205 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0001822 Census Yes 60 0.1333333333333333 291 34 0.0755555555555555 4
PCSK5-205 PCSK5 Q92824 Proprotein convertase subtilisin/kexin type 5 chr9 GO:0001822 Not Cancer Driver No 259 0.139247311827957 170 20 0.010752688172043 0
PCSK9-201 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0001822 Not Cancer Driver No 73 0.1054913294797687 150 20 0.0289017341040462 8
PKD1-201 PKD1 P98161 Polycystin-1 chr16 GO:0001822 Not Cancer Driver No 299 0.0694864048338368 695 50 0.0116198001394376 91
PKD1L3-201 PKD1L3 Q7Z443 Polycystin-1-like protein 3 chr16 GO:0001822 Not Cancer Driver No 0 0.0 148 0 0.0 0
PKHD1-202 PKHD1 P08F94 Fibrocystin chr6 GO:0001822 Not Cancer Driver No 610 0.1497299950908198 415 62 0.0152184585174275 91
PLXND1-201 PLXND1 Q9Y4D7 Plexin-D1 chr3 GO:0001822 Not Cancer Driver No 196 0.1018181818181818 321 26 0.0135064935064935 0
PRDM1-203 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0001822 Census, Compendium Yes 122 0.1478787878787879 339 56 0.0678787878787878 0
PROX1-201 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0001822 Not Cancer Driver No 151 0.2048846675712347 539 116 0.1573948439620081 0
PTCD2-202 PTCD2 Q8WV60 Pentatricopeptide repeat-containing protein 2, mitochondrial chr5 GO:0001822 Not Cancer Driver No 31 0.0798969072164948 9 0 0.0 0
PTK7-202 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 GO:0001822 Not Cancer Driver No 113 0.105607476635514 359 43 0.0401869158878504 0
PYGO1-201 PYGO1 Q9Y3Y4 Pygopus homolog 1 chr15 GO:0001822 Not Cancer Driver No 40 0.0954653937947494 364 36 0.0859188544152744 0
PYGO2-202 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 GO:0001822 Not Cancer Driver No 44 0.1083743842364532 341 39 0.0960591133004926 0
REN-201 REN P00797 Renin chr1 GO:0001822 Not Cancer Driver No 46 0.1133004926108374 10 0 0.0 3
RGN-203 RGN Q15493 Regucalcin chrX GO:0001822 Not Cancer Driver No 31 0.1036789297658862 15 0 0.0 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 GO:0001822 Census, Compendium Yes 92 0.4766839378238341 46 12 0.0621761658031088 2
RPGRIP1L-212 RPGRIP1L Q68CZ1 Protein fantom chr16 GO:0001822 Not Cancer Driver No 127 0.0965779467680608 587 73 0.0555133079847908 8
RRM2B-201 RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0001822 Not Cancer Driver No 31 0.0883190883190883 32 4 0.0113960113960113 9
SALL1-201 SALL1 Q9NSC2 Sal-like protein 1 chr16 GO:0001822 Not Cancer Driver No 372 0.2809667673716012 952 270 0.2039274924471299 0
SERPINF1-201 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0001822 Not Cancer Driver No 37 0.0885167464114832 57 5 0.0119617224880382 0
SGPL1-202 SGPL1 O95470 Sphingosine-1-phosphate lyase 1 chr10 GO:0001822 Not Cancer Driver No 46 0.0809859154929577 19 3 0.005281690140845 2
SIX1-205 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0001822 Census, Compendium Yes 27 0.0950704225352112 144 16 0.056338028169014 7
SIX2-201 SIX2 Q9NPC8 Homeobox protein SIX2 chr2 GO:0001822 Census Yes 38 0.1305841924398625 151 16 0.0549828178694158 0
SLC34A1-201 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0001822 Not Cancer Driver No 69 0.107981220657277 46 8 0.0125195618153364 8
SNX17-201 SNX17 Q15036 Sorting nexin-17 chr2 GO:0001822 Not Cancer Driver No 46 0.0978723404255319 118 11 0.0234042553191489 0
SOX11-201 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0001822 Not Cancer Driver No 54 0.1224489795918367 370 47 0.1065759637188208 23
STRA6-202 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 GO:0001822 Not Cancer Driver No 62 0.0929535232383808 84 13 0.0194902548725637 6
SULF1-202 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0001822 Not Cancer Driver No 183 0.2101033295063145 269 61 0.0700344431687715 0
SULF2-213 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 GO:0001822 Not Cancer Driver No 126 0.1448275862068965 142 16 0.0183908045977011 0
TBC1D32-204 TBC1D32 Q96NH3 Protein broad-minded chr6 GO:0001822 Not Cancer Driver No 124 0.0986475735879077 113 14 0.011137629276054 0
TCF21-202 TCF21 O43680 Transcription factor 21 chr6 GO:0001822 Not Cancer Driver No 44 0.2458100558659217 122 31 0.1731843575418994 0
TFAP2A-203 TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0001822 Not Cancer Driver No 54 0.123006833712984 277 32 0.0728929384965831 4
TFAP2B-202 TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0001822 Not Cancer Driver No 77 0.1673913043478261 306 55 0.1195652173913043 5
TGFB2-202 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0001822 Not Cancer Driver No 44 0.1062801932367149 47 5 0.0120772946859903 4
TGFBR1-202 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0001822 Not Cancer Driver No 57 0.1133200795228628 23 3 0.0059642147117296 13
TIPARP-201 TIPARP Q7Z3E1 Protein mono-ADP-ribosyltransferase TIPARP chr3 GO:0001822 Not Cancer Driver No 44 0.0669710806697108 202 16 0.0243531202435312 0
TNS2-201 TNS2 Q63HR2 Tensin-2 chr12 GO:0001822 Not Cancer Driver No 97 0.0688431511710433 800 47 0.0333569907735983 0
TP73-208 TP73 O15350 Tumor protein p73 chr1 GO:0001822 Not Cancer Driver No 67 0.1053459119496855 446 45 0.070754716981132 0
TRAF3IP1-201 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 GO:0001822 Not Cancer Driver No 46 0.0665701881331403 512 33 0.0477568740955137 3
TRAF3IP2-201 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0001822 Not Cancer Driver No 47 0.0818815331010452 413 34 0.0592334494773519 2
TREX1-205 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0001822 Not Cancer Driver No 24 0.0764331210191082 98 7 0.0222929936305732 17
TSC1-201 TSC1 Q92574 Hamartin chr9 GO:0001822 Census, Compendium Yes 94 0.0807560137457044 735 53 0.0455326460481099 11
UPK3A-201 UPK3A O75631 Uroplakin-3a chr22 GO:0001822 Not Cancer Driver No 34 0.1184668989547038 66 9 0.0313588850174216 0
VEGFA-226 VEGFA P15692 Vascular endothelial growth factor A, long form chr6 GO:0001822 Not Cancer Driver No 24 0.060759493670886 215 9 0.0227848101265822 0
WDPCP-201 WDPCP O95876 WD repeat-containing and planar cell polarity effector protein fritz homolog chr2 GO:0001822 Not Cancer Driver No 85 0.113941018766756 75 12 0.0160857908847185 1
WFS1-201 WFS1 O76024 Wolframin chr4 GO:0001822 Not Cancer Driver No 78 0.0876404494382022 205 11 0.0123595505617977 40
WNT4-201 WNT4 P56705 Protein Wnt-4 chr1 GO:0001822 Not Cancer Driver No 25 0.0712250712250712 39 2 0.0056980056980056 5
WNT5A-201 WNT5A P41221 Protein Wnt-5a chr3 GO:0001822 Not Cancer Driver No 42 0.1105263157894736 0 0 0.0 2
ZBTB14-209 ZBTB14 O43829 Zinc finger and BTB domain-containing protein 14 chr18 GO:0001822 Not Cancer Driver No 51 0.1135857461024498 207 19 0.042316258351893 0
ZNG1A-202 ZNG1A Q9BRT8 Zinc-regulated GTPase metalloprotein activator 1A chr9 GO:0001822 Not Cancer Driver No 20 0.050632911392405 59 4 0.010126582278481 0