Total number of protein in "GO:0001889" GO term: 77
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACADM-202 | ACADM | P11310 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | chr1 | GO:0001889 | Not Cancer Driver | No | 39 | 0.0926365795724465 | 42 | 2 | 0.004750593824228 | 19 |
| ACAT1-201 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | GO:0001889 | Not Cancer Driver | No | 29 | 0.0679156908665105 | 32 | 1 | 0.0023419203747072 | 10 |
| ACO2-201 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | GO:0001889 | Not Cancer Driver | No | 77 | 0.0987179487179487 | 172 | 16 | 0.0205128205128205 | 5 |
| ADA-201 | ADA | P00813 | Adenosine deaminase | chr20 | GO:0001889 | Not Cancer Driver | No | 43 | 0.1184573002754821 | 45 | 9 | 0.024793388429752 | 22 |
| ALDH1A2-201 | ALDH1A2 | O94788 | Retinal dehydrogenase 2 | chr15 | GO:0001889 | Not Cancer Driver | No | 72 | 0.138996138996139 | 56 | 12 | 0.0231660231660231 | 3 |
| ARF6-201 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | GO:0001889 | Not Cancer Driver | No | 16 | 0.0914285714285714 | 5 | 0 | 0.0 | 0 |
| ARID5B-201 | ARID5B | Q14865 | AT-rich interactive domain-containing protein 5B | chr10 | GO:0001889 | Not Cancer Driver | No | 133 | 0.1119528619528619 | 770 | 82 | 0.069023569023569 | 0 |
| ASS1-201 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | GO:0001889 | Not Cancer Driver | No | 50 | 0.1213592233009708 | 63 | 8 | 0.0194174757281553 | 66 |
| ATF2-201 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0001889 | Not Cancer Driver | No | 42 | 0.0831683168316831 | 451 | 36 | 0.0712871287128712 | 0 |
| ATP7A-201 | ATP7A | Q04656 | Copper-transporting ATPase 1 | chrX | GO:0001889 | Not Cancer Driver | No | 152 | 0.1013333333333333 | 171 | 36 | 0.024 | 48 |
| BAAT-201 | BAAT | Q14032 | Bile acid-CoA:amino acid N-acyltransferase | chr9 | GO:0001889 | Not Cancer Driver | No | 65 | 0.1555023923444976 | 10 | 3 | 0.0071770334928229 | 1 |
| CAD-201 | CAD | P27708 | CAD protein | chr2 | GO:0001889 | Not Cancer Driver | No | 211 | 0.0948314606741573 | 368 | 27 | 0.0121348314606741 | 1 |
| CADM1-203 | CADM1 | Q9BY67 | Cell adhesion molecule 1 | chr11 | GO:0001889 | Not Cancer Driver | No | 75 | 0.169683257918552 | 103 | 19 | 0.0429864253393665 | 0 |
| CDK5RAP3-201 | CDK5RAP3 | Q96JB5 | CDK5 regulatory subunit-associated protein 3 | chr17 | GO:0001889 | Not Cancer Driver | No | 37 | 0.0731225296442687 | 99 | 18 | 0.0355731225296442 | 0 |
| CDKN2B-201 | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | GO:0001889 | Not Cancer Driver | No | 14 | 0.1014492753623188 | 67 | 2 | 0.0144927536231884 | 0 |
| CEBPA-201 | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0001889 | Census, Compendium | Yes | 10 | 0.0279329608938547 | 343 | 10 | 0.0279329608938547 | 1 |
| CEBPG-201 | CEBPG | P53567 | CCAAT/enhancer-binding protein gamma | chr19 | GO:0001889 | Not Cancer Driver | No | 10 | 0.0666666666666666 | 141 | 9 | 0.06 | 0 |
| CITED2-201 | CITED2 | Q99967 | Cbp/p300-interacting transactivator 2 | chr6 | GO:0001889 | Not Cancer Driver | No | 22 | 0.0814814814814814 | 232 | 19 | 0.0703703703703703 | 0 |
| COBL-201 | COBL | O75128 | Protein cordon-bleu | chr7 | GO:0001889 | Not Cancer Driver | No | 177 | 0.1403647898493259 | 1146 | 159 | 0.1260904044409199 | 0 |
| DUT-201 | DUT | P33316 | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | chr15 | GO:0001889 | Not Cancer Driver | No | 12 | 0.0476190476190476 | 128 | 6 | 0.0238095238095238 | 1 |
| ELK1-203 | ELK1 | P19419 | ETS domain-containing protein Elk-1 | chrX | GO:0001889 | Not Cancer Driver | No | 39 | 0.0911214953271028 | 329 | 26 | 0.0607476635514018 | 0 |
| ERRFI1-201 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0001889 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 299 | 23 | 0.0497835497835497 | 0 |
| FPGS-203 | FPGS | Q05932 | Folylpolyglutamate synthase, mitochondrial | chr9 | GO:0001889 | Not Cancer Driver | No | 50 | 0.0851788756388415 | 142 | 15 | 0.0255536626916524 | 0 |
| GATA6-201 | GATA6 | Q92908 | Transcription factor GATA-6 | chr18 | GO:0001889 | Not Cancer Driver | No | 45 | 0.0756302521008403 | 478 | 39 | 0.0655462184873949 | 15 |
| GFER-201 | GFER | P55789 | FAD-linked sulfhydryl oxidase ALR | chr16 | GO:0001889 | Not Cancer Driver | No | 9 | 0.0439024390243902 | 97 | 3 | 0.0146341463414634 | 1 |
| HES1-201 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0001889 | Not Cancer Driver | No | 35 | 0.125 | 227 | 30 | 0.1071428571428571 | 0 |
| HGF-201 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0001889 | Compendium | Yes | 196 | 0.2692307692307692 | 43 | 16 | 0.0219780219780219 | 0 |
| HLX-201 | HLX | Q14774 | H2.0-like homeobox protein | chr1 | GO:0001889 | Not Cancer Driver | No | 90 | 0.1844262295081967 | 416 | 80 | 0.1639344262295081 | 0 |
| HMGCS2-201 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0001889 | Not Cancer Driver | No | 65 | 0.1279527559055118 | 29 | 2 | 0.0039370078740157 | 19 |
| HNF1A-201 | HNF1A | P20823 | Hepatocyte nuclear factor 1-alpha | chr12 | GO:0001889 | Census, Compendium | Yes | 83 | 0.1315372424722662 | 567 | 66 | 0.1045958795562599 | 38 |
| HNRNPD-201 | HNRNPD | Q14103 | Heterogeneous nuclear ribonucleoprotein D0 | chr4 | GO:0001889 | Not Cancer Driver | No | 28 | 0.0788732394366197 | 206 | 12 | 0.0338028169014084 | 0 |
| IGF2R-201 | IGF2R | P11717 | Cation-independent mannose-6-phosphate receptor | chr6 | GO:0001889 | Not Cancer Driver | No | 233 | 0.0935367322360497 | 257 | 13 | 0.0052187876354877 | 0 |
| JARID2-201 | JARID2 | Q92833 | Protein Jumonji | chr6 | GO:0001889 | Not Cancer Driver | No | 144 | 0.1155698234349919 | 724 | 87 | 0.0698234349919743 | 0 |
| LSR-214 | LSR | Q86X29 | Lipolysis-stimulated lipoprotein receptor | chr19 | GO:0001889 | Not Cancer Driver | No | 71 | 0.1093990755007704 | 330 | 37 | 0.0570107858243451 | 0 |
| MAN2A1-201 | MAN2A1 | Q16706 | Alpha-mannosidase 2 | chr5 | GO:0001889 | Not Cancer Driver | No | 121 | 0.1057692307692307 | 83 | 6 | 0.0052447552447552 | 0 |
| MED1-201 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0001889 | Not Cancer Driver | No | 81 | 0.0512333965844402 | 1104 | 50 | 0.0316255534471853 | 0 |
| MET-202 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0001889 | Census, Compendium | Yes | 161 | 0.1158273381294964 | 62 | 10 | 0.0071942446043165 | 16 |
| MPST-201 | MPST | P25325 | 3-mercaptopyruvate sulfurtransferase | chr22 | GO:0001889 | Not Cancer Driver | No | 18 | 0.0606060606060606 | 72 | 9 | 0.0303030303030303 | 0 |
| NAGLU-201 | NAGLU | P54802 | Alpha-N-acetylglucosaminidase | chr17 | GO:0001889 | Not Cancer Driver | No | 57 | 0.0767160161507402 | 18 | 0 | 0.0 | 61 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0001889 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NKX2-8-201 | NKX2-8 | O15522 | Homeobox protein Nkx-2.8 | chr14 | GO:0001889 | Not Cancer Driver | No | 13 | 0.0543933054393305 | 163 | 13 | 0.0543933054393305 | 0 |
| NODAL-201 | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0001889 | Not Cancer Driver | No | 34 | 0.0979827089337175 | 34 | 9 | 0.0259365994236311 | 4 |
| NOTCH1-204 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0001889 | Census, Compendium | Yes | 312 | 0.1221135029354207 | 690 | 71 | 0.0277886497064579 | 3 |
| NPC1-201 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | GO:0001889 | Not Cancer Driver | No | 113 | 0.0884194053208137 | 25 | 0 | 0.0 | 135 |
| ONECUT1-201 | ONECUT1 | Q9UBC0 | Hepatocyte nuclear factor 6 | chr15 | GO:0001889 | Not Cancer Driver | No | 57 | 0.1225806451612903 | 409 | 47 | 0.1010752688172043 | 0 |
| ONECUT2-202 | ONECUT2 | O95948 | One cut domain family member 2 | chr18 | GO:0001889 | Not Cancer Driver | No | 58 | 0.115079365079365 | 409 | 39 | 0.0773809523809523 | 0 |
| OTC-201 | OTC | P00480 | Ornithine transcarbamylase, mitochondrial | chrX | GO:0001889 | Not Cancer Driver | No | 53 | 0.1497175141242938 | 24 | 3 | 0.0084745762711864 | 92 |
| PCSK9-201 | PCSK9 | Q8NBP7 | Proprotein convertase subtilisin/kexin type 9 | chr1 | GO:0001889 | Not Cancer Driver | No | 73 | 0.1054913294797687 | 150 | 20 | 0.0289017341040462 | 8 |
| PDX1-201 | PDX1 | P52945 | Pancreas/duodenum homeobox protein 1 | chr13 | GO:0001889 | Not Cancer Driver | No | 23 | 0.0812720848056537 | 239 | 16 | 0.0565371024734982 | 0 |
| PHF2-201 | PHF2 | O75151 | Lysine-specific demethylase PHF2 | chr9 | GO:0001889 | Not Cancer Driver | No | 101 | 0.0921532846715328 | 728 | 69 | 0.062956204379562 | 0 |
| PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0001889 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
| PKD1-201 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0001889 | Not Cancer Driver | No | 299 | 0.0694864048338368 | 695 | 50 | 0.0116198001394376 | 91 |
| PKD2-201 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0001889 | Not Cancer Driver | No | 88 | 0.0909090909090909 | 376 | 30 | 0.03099173553719 | 9 |
| PRKCSH-209 | PRKCSH | P14314 | Glucosidase 2 subunit beta | chr19 | GO:0001889 | Not Cancer Driver | No | 47 | 0.0890151515151515 | 320 | 28 | 0.053030303030303 | 0 |
| PROX1-201 | PROX1 | Q92786 | Prospero homeobox protein 1 | chr1 | GO:0001889 | Not Cancer Driver | No | 151 | 0.2048846675712347 | 539 | 116 | 0.1573948439620081 | 0 |
| PTCD2-202 | PTCD2 | Q8WV60 | Pentatricopeptide repeat-containing protein 2, mitochondrial | chr5 | GO:0001889 | Not Cancer Driver | No | 31 | 0.0798969072164948 | 9 | 0 | 0.0 | 0 |
| RARA-201 | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0001889 | Census, Compendium | Yes | 60 | 0.1298701298701298 | 167 | 14 | 0.0303030303030303 | 0 |
| RB1CC1-201 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | GO:0001889 | Not Cancer Driver | No | 150 | 0.0941028858218318 | 579 | 56 | 0.0351317440401505 | 0 |
| RELA-202 | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0001889 | Compendium | Yes | 53 | 0.0961887477313974 | 401 | 32 | 0.058076225045372 | 0 |
| RHBDD3-201 | RHBDD3 | Q9Y3P4 | Rhomboid domain-containing protein 3 | chr22 | GO:0001889 | Not Cancer Driver | No | 19 | 0.0492227979274611 | 147 | 12 | 0.0310880829015544 | 0 |
| RPGRIP1L-212 | RPGRIP1L | Q68CZ1 | Protein fantom | chr16 | GO:0001889 | Not Cancer Driver | No | 127 | 0.0965779467680608 | 587 | 73 | 0.0555133079847908 | 8 |
| SEC63-201 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | GO:0001889 | Not Cancer Driver | No | 67 | 0.0881578947368421 | 267 | 25 | 0.0328947368421052 | 0 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0001889 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| SOD2-210 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0001889 | Not Cancer Driver | No | 21 | 0.0945945945945946 | 25 | 3 | 0.0135135135135135 | 0 |
| SP3-201 | SP3 | Q02447 | Transcription factor Sp3 | chr2 | GO:0001889 | Not Cancer Driver | No | 50 | 0.0640204865556978 | 588 | 34 | 0.0435339308578745 | 0 |
| SRD5A1-201 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0001889 | Not Cancer Driver | No | 26 | 0.1003861003861003 | 0 | 0 | 0.0 | 0 |
| TGFBR3-201 | TGFBR3 | Q03167 | Transforming growth factor beta receptor type 3 | chr1 | GO:0001889 | Not Cancer Driver | No | 104 | 0.1222091656874265 | 268 | 36 | 0.0423031727379553 | 0 |
| UGT1A1-201 | UGT1A1 | P22309 | UDP-glucuronosyltransferase 1A1 | chr2 | GO:0001889 | Not Cancer Driver | No | 38 | 0.0712945590994371 | 11 | 0 | 0.0 | 53 |
| UGT1A10-201 | UGT1A10 | Q9HAW8 | UDP-glucuronosyltransferase 1A10 | chr2 | GO:0001889 | Not Cancer Driver | No | 92 | 0.1735849056603773 | 11 | 0 | 0.0 | 0 |
| UGT1A7-201 | UGT1A7 | Q9HAW7 | UDP-glucuronosyltransferase 1A7 | chr2 | GO:0001889 | Not Cancer Driver | No | 79 | 0.1490566037735849 | 11 | 0 | 0.0 | 0 |
| UGT1A8-201 | UGT1A8 | Q9HAW9 | UDP-glucuronosyltransferase 1A8 | chr2 | GO:0001889 | Not Cancer Driver | No | 76 | 0.1433962264150943 | 11 | 0 | 0.0 | 0 |
| UGT1A9-201 | UGT1A9 | O60656 | UDP-glucuronosyltransferase 1A9 | chr2 | GO:0001889 | Not Cancer Driver | No | 83 | 0.1566037735849056 | 11 | 0 | 0.0 | 0 |
| UPB1-201 | UPB1 | Q9UBR1 | Beta-ureidopropionase | chr22 | GO:0001889 | Not Cancer Driver | No | 44 | 0.1145833333333333 | 22 | 6 | 0.015625 | 8 |
| UPF2-202 | UPF2 | Q9HAU5 | Regulator of nonsense transcripts 2 | chr10 | GO:0001889 | Not Cancer Driver | No | 112 | 0.0880503144654088 | 634 | 63 | 0.0495283018867924 | 0 |
| WNT4-201 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0001889 | Not Cancer Driver | No | 25 | 0.0712250712250712 | 39 | 2 | 0.0056980056980056 | 5 |
| XBP1-201 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0001889 | Not Cancer Driver | No | 11 | 0.0421455938697318 | 171 | 6 | 0.0229885057471264 | 0 |
| ZMPSTE24-201 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0001889 | Not Cancer Driver | No | 46 | 0.0968421052631579 | 23 | 0 | 0.0 | 3 |