Total number of protein in "GO:0001938" GO term: 72
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVRL1-201 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0001938 | Not Cancer Driver | No | 80 | 0.1590457256461232 | 60 | 10 | 0.0198807157057654 | 64 |
| AGGF1-201 | AGGF1 | Q8N302 | Angiogenic factor with G patch and FHA domains 1 | chr5 | GO:0001938 | Not Cancer Driver | No | 68 | 0.0952380952380952 | 583 | 60 | 0.0840336134453781 | 1 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0001938 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| AKT3-217 | AKT3 | Q9Y243 | RAC-gamma serine/threonine-protein kinase | chr1 | GO:0001938 | Census, Compendium | Yes | 71 | 0.1482254697286012 | 131 | 19 | 0.0396659707724425 | 3 |
| ANG-202 | ANG | P03950 | Angiogenin | chr14 | GO:0001938 | Not Cancer Driver | No | 11 | 0.0748299319727891 | 36 | 2 | 0.0136054421768707 | 13 |
| ARNT-202 | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | GO:0001938 | Census | Yes | 61 | 0.0773130544993662 | 511 | 47 | 0.0595690747782002 | 0 |
| BMP4-201 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0001938 | Not Cancer Driver | No | 69 | 0.1691176470588235 | 142 | 20 | 0.0490196078431372 | 5 |
| BMP6-201 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0001938 | Not Cancer Driver | No | 79 | 0.1539961013645224 | 228 | 41 | 0.0799220272904483 | 6 |
| CAV2-201 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0001938 | Not Cancer Driver | No | 13 | 0.0802469135802469 | 5 | 2 | 0.0123456790123456 | 0 |
| CCL11-201 | CCL11 | P51671 | Eotaxin | chr17 | GO:0001938 | Not Cancer Driver | No | 15 | 0.1546391752577319 | 14 | 3 | 0.0309278350515463 | 0 |
| CCL24-201 | CCL24 | O00175 | C-C motif chemokine 24 | chr7 | GO:0001938 | Not Cancer Driver | No | 18 | 0.1512605042016806 | 23 | 3 | 0.0252100840336134 | 0 |
| CCL26-201 | CCL26 | Q9Y258 | C-C motif chemokine 26 | chr7 | GO:0001938 | Not Cancer Driver | No | 6 | 0.0638297872340425 | 0 | 0 | 0.0 | 0 |
| CCR3-202 | CCR3 | P51677 | C-C chemokine receptor type 3 | chr3 | GO:0001938 | Not Cancer Driver | No | 66 | 0.1859154929577464 | 0 | 0 | 0.0 | 0 |
| CDH13-209 | CDH13 | P55290 | Cadherin-13 | chr16 | GO:0001938 | Not Cancer Driver | No | 128 | 0.1795231416549789 | 236 | 47 | 0.0659186535764375 | 0 |
| CXCL12-203 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:0001938 | Not Cancer Driver | No | 8 | 0.086021505376344 | 0 | 0 | 0.0 | 0 |
| ECM1-202 | ECM1 | Q16610 | Extracellular matrix protein 1 | chr1 | GO:0001938 | Not Cancer Driver | No | 66 | 0.1222222222222222 | 224 | 23 | 0.0425925925925925 | 1 |
| EGF-201 | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0001938 | Not Cancer Driver | No | 149 | 0.1234465617232808 | 193 | 22 | 0.0182270091135045 | 1 |
| EGFL7-201 | EGFL7 | Q9UHF1 | Epidermal growth factor-like protein 7 | chr9 | GO:0001938 | Not Cancer Driver | No | 23 | 0.0842490842490842 | 36 | 3 | 0.0109890109890109 | 0 |
| EGR3-201 | EGR3 | Q06889 | Early growth response protein 3 | chr8 | GO:0001938 | Not Cancer Driver | No | 38 | 0.0981912144702842 | 253 | 26 | 0.0671834625322997 | 0 |
| EMC10-201 | EMC10 | Q5UCC4 | ER membrane protein complex subunit 10 | chr19 | GO:0001938 | Not Cancer Driver | No | 18 | 0.0687022900763358 | 111 | 13 | 0.049618320610687 | 0 |
| ENST00000560629 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0001938 | Not Cancer Driver | No | 92 | 0.1168996188055908 | 68 | 6 | 0.0076238881829733 | 27 |
| F3-201 | F3 | P13726 | Tissue factor | chr1 | GO:0001938 | Not Cancer Driver | No | 18 | 0.0610169491525423 | 61 | 4 | 0.0135593220338983 | 0 |
| FGF10-201 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0001938 | Not Cancer Driver | No | 42 | 0.2019230769230769 | 34 | 8 | 0.0384615384615384 | 2 |
| FGF2-201 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0001938 | Not Cancer Driver | No | 17 | 0.0590277777777777 | 183 | 5 | 0.0173611111111111 | 0 |
| FGF7-201 | FGF7 | P21781 | Fibroblast growth factor 7 | chr15 | GO:0001938 | Not Cancer Driver | No | 26 | 0.134020618556701 | 22 | 4 | 0.0206185567010309 | 0 |
| FLT4-201 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0001938 | Census, Compendium | Yes | 203 | 0.1489361702127659 | 259 | 33 | 0.0242112986060161 | 14 |
| GDF2-201 | GDF2 | Q9UK05 | Growth/differentiation factor 2 | chr10 | GO:0001938 | Not Cancer Driver | No | 106 | 0.247086247086247 | 130 | 40 | 0.0932400932400932 | 3 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0001938 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| HMGB2-201 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0001938 | Not Cancer Driver | No | 26 | 0.124401913875598 | 207 | 26 | 0.124401913875598 | 0 |
| HSPG2-203 | HSPG2 | P98160 | Basement membrane-specific heparan sulfate proteoglycan core protein | chr1 | GO:0001938 | Compendium | Yes | 414 | 0.0942837622409474 | 1724 | 160 | 0.0364381689820086 | 1 |
| HTR2B-201 | HTR2B | P41595 | 5-hydroxytryptamine receptor 2B | chr2 | GO:0001938 | Not Cancer Driver | No | 25 | 0.0519750519750519 | 23 | 0 | 0.0 | 0 |
| IL10-202 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0001938 | Not Cancer Driver | No | 17 | 0.095505617977528 | 23 | 1 | 0.0056179775280898 | 0 |
| ITGB3-201 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0001938 | Not Cancer Driver | No | 92 | 0.116751269035533 | 68 | 5 | 0.0063451776649746 | 28 |
| KDR-201 | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0001938 | Census, Compendium | Yes | 276 | 0.2035398230088495 | 276 | 40 | 0.0294985250737463 | 2 |
| LRG1-201 | LRG1 | P02750 | Leucine-rich alpha-2-glycoprotein | chr19 | GO:0001938 | Not Cancer Driver | No | 49 | 0.1412103746397694 | 29 | 7 | 0.0201729106628242 | 0 |
| MYDGF-201 | MYDGF | Q969H8 | Myeloid-derived growth factor | chr19 | GO:0001938 | Not Cancer Driver | No | 16 | 0.0924855491329479 | 26 | 4 | 0.0231213872832369 | 0 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0001938 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NR4A1-204 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | GO:0001938 | Not Cancer Driver | No | 52 | 0.0869565217391304 | 252 | 24 | 0.040133779264214 | 0 |
| NRARP-201 | NRARP | Q7Z6K4 | Notch-regulated ankyrin repeat-containing protein | chr9 | GO:0001938 | Not Cancer Driver | No | 10 | 0.087719298245614 | 11 | 1 | 0.0087719298245614 | 0 |
| NRAS-201 | NRAS | P01111 | GTPase NRas | chr1 | GO:0001938 | Census, Compendium | Yes | 272 | 1.439153439153439 | 10 | 0 | 0.0 | 12 |
| NRP1-206 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0001938 | Compendium | Yes | 112 | 0.1213434452871072 | 212 | 25 | 0.0270855904658721 | 0 |
| NRP2-204 | NRP2 | O60462 | Neuropilin-2 | chr2 | GO:0001938 | Not Cancer Driver | No | 126 | 0.1353383458646616 | 211 | 34 | 0.0365198711063372 | 0 |
| PDCD6-201 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | GO:0001938 | Not Cancer Driver | No | 16 | 0.0837696335078534 | 26 | 1 | 0.0052356020942408 | 0 |
| PDCL3-201 | PDCL3 | Q9H2J4 | Phosducin-like protein 3 | chr2 | GO:0001938 | Not Cancer Driver | No | 36 | 0.1506276150627615 | 73 | 11 | 0.0460251046025104 | 0 |
| PDGFB-201 | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0001938 | Census | Yes | 30 | 0.1244813278008298 | 99 | 16 | 0.0663900414937759 | 2 |
| PGF-202 | PGF | P49763 | Placenta growth factor | chr14 | GO:0001938 | Not Cancer Driver | No | 15 | 0.0678733031674208 | 72 | 2 | 0.0090497737556561 | 0 |
| PIK3CD-202 | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0001938 | Not Cancer Driver | No | 116 | 0.1111111111111111 | 61 | 8 | 0.0076628352490421 | 1 |
| PLXNB3-201 | PLXNB3 | Q9ULL4 | Plexin-B3 | chrX | GO:0001938 | Not Cancer Driver | No | 168 | 0.0880041906757464 | 358 | 30 | 0.0157150340492404 | 0 |
| POLD4-201 | POLD4 | Q9HCU8 | DNA polymerase delta subunit 4 | chr11 | GO:0001938 | Not Cancer Driver | No | 7 | 0.0654205607476635 | 51 | 3 | 0.02803738317757 | 0 |
| PPP1R16B-201 | PPP1R16B | Q96T49 | Protein phosphatase 1 regulatory inhibitor subunit 16B | chr20 | GO:0001938 | Not Cancer Driver | No | 99 | 0.1746031746031746 | 220 | 54 | 0.0952380952380952 | 0 |
| PRKCA-202 | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0001938 | Not Cancer Driver | No | 70 | 0.1041666666666666 | 155 | 17 | 0.025297619047619 | 0 |
| PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0001938 | Census | Yes | 164 | 0.1798245614035087 | 190 | 31 | 0.0339912280701754 | 2 |
| PRKD2-201 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0001938 | Compendium | Yes | 89 | 0.1013667425968109 | 247 | 26 | 0.0296127562642369 | 0 |
| PROX1-201 | PROX1 | Q92786 | Prospero homeobox protein 1 | chr1 | GO:0001938 | Not Cancer Driver | No | 151 | 0.2048846675712347 | 539 | 116 | 0.1573948439620081 | 0 |
| RICTOR-202 | RICTOR | Q6R327 | Rapamycin-insensitive companion of mTOR | chr5 | GO:0001938 | Not Cancer Driver | No | 144 | 0.0843091334894613 | 365 | 34 | 0.0199063231850117 | 0 |
| RPTOR-201 | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0001938 | Not Cancer Driver | No | 149 | 0.1116104868913857 | 242 | 18 | 0.0134831460674157 | 0 |
| SCG2-201 | SCG2 | P13521 | Secretogranin-2 | chr2 | GO:0001938 | Not Cancer Driver | No | 95 | 0.1539708265802269 | 532 | 86 | 0.1393841166936791 | 0 |
| SEMA5A-201 | SEMA5A | Q13591 | Semaphorin-5A | chr5 | GO:0001938 | Not Cancer Driver | No | 221 | 0.2057728119180633 | 24 | 2 | 0.0018621973929236 | 0 |
| SIRT1-201 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0001938 | Not Cancer Driver | No | 43 | 0.0575635876840696 | 435 | 19 | 0.0254350736278447 | 0 |
| STAT5A-209 | STAT5A | P42229 | Signal transducer and activator of transcription 5A | chr17 | GO:0001938 | Not Cancer Driver | No | 64 | 0.0806045340050377 | 125 | 7 | 0.008816120906801 | 0 |
| TEK-201 | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0001938 | Not Cancer Driver | No | 145 | 0.1290035587188612 | 126 | 13 | 0.0115658362989323 | 9 |
| TGFBR1-202 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0001938 | Not Cancer Driver | No | 57 | 0.1133200795228628 | 23 | 3 | 0.0059642147117296 | 13 |
| THBS4-201 | THBS4 | P35443 | Thrombospondin-4 | chr5 | GO:0001938 | Not Cancer Driver | No | 99 | 0.1030176899063475 | 282 | 33 | 0.0343392299687825 | 0 |
| TNFSF12-201 | TNFSF12 | O43508 | Tumor necrosis factor ligand superfamily member 12 | chr17 | GO:0001938 | Not Cancer Driver | No | 6 | 0.0240963855421686 | 109 | 3 | 0.0120481927710843 | 0 |
| VASH2-211 | VASH2 | Q86V25 | Tubulinyl-Tyr carboxypeptidase 2 | chr1 | GO:0001938 | Not Cancer Driver | No | 27 | 0.076056338028169 | 107 | 8 | 0.0225352112676056 | 0 |
| VEGFA-226 | VEGFA | P15692 | Vascular endothelial growth factor A, long form | chr6 | GO:0001938 | Not Cancer Driver | No | 24 | 0.060759493670886 | 215 | 9 | 0.0227848101265822 | 0 |
| VEGFB-201 | VEGFB | P49765 | Vascular endothelial growth factor B | chr11 | GO:0001938 | Not Cancer Driver | No | 15 | 0.072463768115942 | 125 | 13 | 0.0628019323671497 | 0 |
| VEGFC-202 | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0001938 | Not Cancer Driver | No | 104 | 0.2482100238663484 | 37 | 8 | 0.0190930787589498 | 0 |
| VEGFD-201 | VEGFD | O43915 | Vascular endothelial growth factor D | chrX | GO:0001938 | Not Cancer Driver | No | 38 | 0.1073446327683615 | 33 | 4 | 0.0112994350282485 | 0 |
| VIP-202 | VIP | P01282 | VIP peptides | chr6 | GO:0001938 | Not Cancer Driver | No | 52 | 0.3058823529411765 | 78 | 22 | 0.1294117647058823 | 0 |
| WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0001938 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |
| ZNF580-201 | ZNF580 | Q9UK33 | Zinc finger protein 580 | chr19 | GO:0001938 | Not Cancer Driver | No | 1 | 0.005813953488372 | 154 | 1 | 0.005813953488372 | 0 |